Biomedical Engineering

, Volume 53, Issue 4, pp 244–248 | Cite as

Regeneration of Articular Cartilage in Experimental Osteoarthrosis after Injection of a Complex Polyacrylamide-Hyaluronic Gel

  • V. V. ZarEmail author
  • A. B. Shekhter
  • E. N. Sukhanov
  • M. V. Zar

The regenerative capacity of articular cartilage was assessed after injection of Matricin polyacrylamide-hyaluronic gel into the knee joints of nine rabbits with a model of osteoarthrosis. Matricin decreased dystrophic and destructive changes in articular cartilage previously induced by exposure to papain solution and produced a significant increase in the regenerative capacity of the damaged hyaline cartilage.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • V. V. Zar
    • 1
    Email author
  • A. B. Shekhter
    • 2
  • E. N. Sukhanov
    • 3
  • M. V. Zar
    • 2
  1. 1.M. F. Vladimirsky Moscow Regional Research and Clinical InstituteMoscowRussia
  2. 2.Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical UniversityMinistry of Health of the Russian FederationMoscowRussia
  3. 3.Moscow Regional Hospital for War VeteransZhilinoRussia

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