It is known that both exercise and aging influence neuromuscular performance; however their effects on post-exercise recovery are largely unknown. To examine how exercise training and aging might affect post-exercise recovery, the function of muscles taken from young, and aged male rats assigned to exercise, or control conditions was assessed with ex vivo procedures using indirect (nerve endings), and direct (sarcolemma) stimulation at different times (Initial, Final min of, and Recovery i.e. 1 min post, from 5 min of stimulation). Results revealed that initially, strength of indirectly stimulated young, male muscles was significantly (P = 0.05) greater than aged ones, but after continuous stimulation, aged and young muscles displayed similar strength, and controls showed more strength than trained muscles (P = 0.02). All groups except young controls exhibited significant recovery with 1 min of rest (P = 0.03). Compared to indirect stimulation, direct stimulation resulted in greater peak tension at each time point examined (P < 0.05); young muscles again were stronger than aged ones initially (P = 0.003), but not by the conclusion of stimulation (P = 0.20). One min following the direct stimulation protocol, no significant recovery was observed by any of the four treatment groups. These data indicate that motor neurons limit neuromuscular function, and that the effects of fatigue are more severe during stimulation of young, compared to aged muscle. Finally, results presented here indicate that age and training status do interact to influence post-exertional recovery, at least among male neuromuscular systems.
Ex vivo Tension Synaptic Conditioning Fatigue
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This work was supported by a Grant from The Foundation for Aging Studies and Exercise Science Research (Grant Number 2016-006).
Abe T, Kojima K, Kearns CF, Yohena H, Fukuda J (2003) Whole body muscle hypertrophy from resistance training: distribution and total mass. Br J Sports Med 37:543–545CrossRefPubMedPubMedCentralGoogle Scholar
Arias E, Heron M, Xu J (2017) United States life tables, 2014. Natl Vital Stat Rep 66:1–64Google Scholar
Bassey EJ, Fiatarone MA, O’Neill EF, Kelly M, Evans WJ, Lipsitz LA (1992) Leg extensor power and functional performance in very old men and women. Clin Sci 82:321–327CrossRefPubMedGoogle Scholar
Bouaziz W, Vogel T, Schmitt E, Kaltenbach G, Geny B, Lang PO (2017) Health benefits of aerobic training programs in adults aged 70 or over: a systematic review. Presse Med 46:794–807CrossRefPubMedGoogle Scholar
Frontera WR, Hughes VA, Fielding RA et al (2000) Aging of skeletal muscle: a 12 year longitudinal study. J Appl Physiol 88:1321–1326CrossRefPubMedGoogle Scholar
Goodpaster BH, Park SW, Harris TB et al (2006) The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci 61:1059–1064CrossRefPubMedGoogle Scholar
Highland KB, Schoomaker A, Rojas W et al (2018) Benefits of the restorative exercise and strength training for operational resilience and excellence yoga program for chronic low back pain in service members: a Pilot Randomized Controlled Trial. Arch Phys Med Rehabil 99:91–98CrossRefPubMedGoogle Scholar
Hughes VA, Frontera WR, Wood M et al (2001) Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health. J Gerontol A Biol Sci Med Sci 56:B209–B217CrossRefPubMedGoogle Scholar
Jenkins ND, Housh TJ, Buckner SL et al (2016) Neuromuscular adaptations after 2 and 4 weeks of 80% versus 30% 1 repetition maximum resistance training to failure. J Strength Cond Res 30:2174–2185CrossRefPubMedGoogle Scholar
Metter EJ, Conwit R, Tobin J, Fozard JL (1997) Age-associated loss of power and strength in the upper extremities in women and men. J Gerontol A Biol Sci Med Sci 52:B267–B276CrossRefPubMedGoogle Scholar
Nogusa Y, Mizugaki A, Hirabayashi-Osada Y et al (2014) Combined supplementation of carbohydrate, alanine, and proline is effective in maintaining blood glucose and increasing endurance performance during long-term exercise in mice. J Nutr Sci Vitaminol (Tokyo) 60:188–193CrossRefGoogle Scholar
Torres SJ, Robinson S, Orellana L et al (2017) Effects of progressive resistance training combined with a protein-enriched lean red meat diet on health-related quality of life in elderly women: secondary analysis of a 4-month cluster randomised controlled trial. Br J Nutr 117:1550–1559. https://doi.org/10.1017/S0007114517001507CrossRefPubMedGoogle Scholar