Bulletin of Experimental Biology and Medicine

, Volume 167, Issue 5, pp 689–693 | Cite as

Effects of Bone Marrow Autotransplantation on the Bone Marrow Neurotransmitter Structures

  • O. V. Vorob’yovaEmail author
  • L. A. Lyubovtseva
  • E. A. Guryanova

Morphological structures involved in local regulation of tissue processes and the neurotransmitters they produce are assumed to play an important role in the pathogenesis of oncological diseases. We studied the dynamics of neurotransmitter cell counts and distribution of catecholamines and serotonin in them and analyzed proliferative activity of hemopoietic cells in the bone marrow of mice after bone marrow autotransplantation. The bone marrow of male mice was studied by fluorescent and immunohistochemical methods after injection of the bone marrow from the same mouse into the caudal vein. The count of neurotransmitter cells and the cell proliferation index increased after bone marrow autotransplantation.

Key Words

bone marrow granular fluorescent cells mast cells catecholamines serotonin 


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • O. V. Vorob’yova
    • 1
    Email author
  • L. A. Lyubovtseva
    • 1
  • E. A. Guryanova
    • 1
  1. 1.Department of Common and Clinical Morphology and Forensic MedicineI. N. Ulyanov Chuvash State UniversityCheboksaryRussia

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