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Study of Biointegration and Elastic-Strength Properties of a New Xenopericardium-Based Biomaterial for Reconstructive Cardiovascular Surgery

  • I. S. FadeevaEmail author
  • M. N. Sorkomov
  • A. I. Zvyagina
  • D. V. Britikov
  • A. S. Sachkov
  • Ya. V. Evstratova
  • R. S Fadeev
  • R. M. Muratov
  • V. S. Akatov
BIOTECHNOLOGIES
  • 8 Downloads

We analyzed biocompatibility, elastic-strength properties, and biointegration potential of a new biomaterial made of xenopericardium for reconstructive cardiovascular surgery. The biomaterial manufactured by the proposed technology demonstrated high biocompatibility and biointegration potential and its elastic-strength properties 2-4-fold surpassed that of native pericardium. The obtained results attested to good prospects of using the proposed technology for preparing biomaterials for reconstructive cardiovascular surgery.

Key Words

xenopericardium-based biomaterials decellularization biointegration elasticstrength characteristics repopulation 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • I. S. Fadeeva
    • 1
    Email author
  • M. N. Sorkomov
    • 2
  • A. I. Zvyagina
    • 1
  • D. V. Britikov
    • 2
  • A. S. Sachkov
    • 2
  • Ya. V. Evstratova
    • 1
  • R. S Fadeev
    • 1
  • R. M. Muratov
    • 2
  • V. S. Akatov
    • 1
  1. 1.Institute of Theoretical and Experimental BiophysicsRussian Academy of SciencesPushchinoRussia
  2. 2.A. N. Bakulev National Medical Research Center of Cardiovascular SurgeryMoscowRussia

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