Advertisement

Protective Properties of Lanthanum Nitrate against Pathogens with Various Morphological and Functional Properties

  • A. S. Vedenkin
  • D. N. VtyurinaEmail author
  • E. A. Grigorieva
  • A. A. Litvin
  • M. G. Mikhaleva
  • T. N. Nikolaeva
  • A. V. Pronin
  • S. V. Stovbun
IMMUNOLOGY AND MICROBIOLOGY
  • 2 Downloads

Dose-dependent protective effects of lanthanum nitrate solution and gel were shown on the model of experimental infection caused by a virulent strain of Shigella flexneri 2a or opportunistic bacteria Klebsiella pneumoniae in outbred and DBA mice.

Key Words

lanthanum nitrate virulent strain of Shigella flexneri 2a opportunistic bacteria Klebsiella pneumoniae type I herpes simplex virus 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Iskandarova SS, Fedorov AI, Iskandarov MI, Bondarenko VZ, Albertyan MP, Imasheva MA. Determination of acute toxicity and cumulative properties of lanthanum nitrate. Trudy Vseross. Nauch.-Issled. Inst. Eksp. Veterinar. im. Ya. R. Kovalenko. 2015;78:234-240. Russian.Google Scholar
  2. 2.
    Anokhina EJ, Litvin AA, Stovbun SV, Jakimuk PV. Patent RU No. 2275184. Protective agent from harmful skin exposure and skin care. Bull. No. 12. Published April 27, 2006.Google Scholar
  3. 3.
    Ashida H, Ogawa M, Mimuro H, Kobayashi T, Sanada T, Sasakawa C. Shigella are versatile mucosal pathogens that circumvent the host innate immune system. Curr. Opin. Immunol. 2011;23(4):448-455.CrossRefGoogle Scholar
  4. 4.
    Berkowitz FE. Antibiotic resistance in bacteria. South Med. J. 1995;88(8):797-804.CrossRefGoogle Scholar
  5. 5.
    Martin RM, Bachman MA. Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae. Front. Cell. Infect. Microbiol. 2018;8:4. doi:  https://doi.org/10.3389/fcimb.2018.00004.CrossRefGoogle Scholar
  6. 6.
    Murphy CN, Mortensen MS, Krogfelt KA, Clegg S. Role of Klebsiella pneumoniae type 1 and type 3 fimbriae in colonizing silicone tubes implanted into the bladders of mice as a model of catheter-associated urinary tract infections. Infect. Immun. 2013;81(8):3009-3017.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • A. S. Vedenkin
    • 1
  • D. N. Vtyurina
    • 1
    Email author
  • E. A. Grigorieva
    • 2
  • A. A. Litvin
    • 1
  • M. G. Mikhaleva
    • 1
  • T. N. Nikolaeva
    • 2
  • A. V. Pronin
    • 2
  • S. V. Stovbun
    • 1
  1. 1.N. N. Semenov Institute of Chemical PhysicsRussian Academy of SciencesMoscowRussia
  2. 2.Laboratory of Natural Immunity, N. F. Gamaleya National Research Center of Epidemiology and MicrobiologyMinistry of Health of the Russian FederationMoscowRussia

Personalised recommendations