Bulletin of Experimental Biology and Medicine

, Volume 164, Issue 4, pp 519–522 | Cite as

Infrared Fluorescent Angiography during Experimental Trachea Transplantation

  • A. L. Akopov
  • G. V. Papayan
  • A. N. Efimov
  • D. B. Nikityuk
  • V. O. Yaprintsev
  • M. A. Magruk
METHODS
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Indocyanine green fluorescence was used for evaluation of the degree of trachea revascularization after its autotransplantation in rabbits (transplantation of 1- and 2-cm segment of the trachea). Intravenous administration of indocyanine green was followed by a significant fluorescence of the substance in microvessels of the trachea over 30-40 sec. Immediately after surgery, fluorescence in the implanted segment was absent, but within 7 days it was completely restored in rabbits receiving transplantation of a 1-cm segment. After transplantation of 2-cm segment of the trachea, fluorescence did not recover, which corresponded to the clinical picture and autopsy results. Thus, fluorescent angiography is an informative method for evaluation of trachea revascularization.

Key Words

trachea transplantation fluorescent diagnostics microcirculation indocyanine green 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • A. L. Akopov
    • 1
  • G. V. Papayan
    • 1
  • A. N. Efimov
    • 1
  • D. B. Nikityuk
    • 2
  • V. O. Yaprintsev
    • 1
  • M. A. Magruk
    • 1
  1. 1.I. P. Pavlov First St. Petersburg State Medical University, Ministry of Health of the Russian FederationSt. PetersburgRussia
  2. 2.Federal Research Center of Nutrition, Biotechnology, and Food SafetyMoscowRussia

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