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Antonie van Leeuwenhoek

, Volume 112, Issue 8, pp 1273–1280 | Cite as

Antibiotic susceptibility of marine Planctomycetes

  • Ofélia Godinho
  • Rita Calisto
  • Lise Øvreås
  • Sandra Quinteira
  • Olga Maria LageEmail author
Short Communication

Abstract

Antimicrobials are naturally produced by microbes and therefore have always been present in their environment, as well as accompanying resistance mechanisms. The antibiotic resistance profile of environmental species is particularly relevant since genetic determinants of resistance can spread through horizontal gene transfer and reach clinically important species. The phylum Planctomycetes comprises Gram-negative bacteria characterised by unusual features and appear to be ubiquitously distributed. Members of this group have recently been characterised as producers of bioactive compounds, namely antimicrobials, but their antibiotic susceptibility profile has been scarcely studied. In this study, the antibiotic susceptibility profile of six phylogenetically distinct strains of Planctomycetes was assessed. All strains showed resistance to beta-lactams, aminoglycosides and glycopeptides. Our results showed that antibiotics which target protein synthesis or DNA replication, with the exception of aminoglycosides, were the most effective against the tested strains. The highest efficacy was observed for chloramphenicol, clindamycin and ciprofloxacin. The highest level of antimicrobial resistance was observed in the uncharacterised novel taxon Planctomyces sp. strain FF15 which was only susceptible to erythromycin and ciprofloxacin.

Keywords

Antibiotic Bacteria Planctomycetes Resistance 

Notes

Acknowledgements

This research was partially supported by the Strategic Funding UID/Multi/04423/2013 through national funds provided by FCT—Foundation for Science and Technology and European Regional Development Fund (ERDF).

Authors’ contribution

OG: experimental work and drafting of the manuscript; RC: experimental work and drafting of the manuscript; LO: drafting and final revision of the manuscript; SQ: experimental work and drafting and final revision of the manuscript; OML: design of the experimental work, experimental work and drafting and final revision of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Supplementary material

10482_2019_1259_MOESM1_ESM.docx (788 kb)
Supplementary material 1 (DOCX 788 kb)

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Departamento de BiologiaUniversidade de AveiroAveiroPortugal
  2. 2.Departamento de Biologia, Faculdade de CiênciasUniversidade do PortoPortoPortugal
  3. 3.CIIMAR/CIMAR–Centro Interdisciplinar de Investigação Marinha e Ambiental–Universidade do Porto, Terminal de Cruzeiros do Porto de LeixõesMatosinhosPortugal
  4. 4.Department of Biological SciencesUniversity of BergenBergenNorway
  5. 5.University Center in Svalbard, UNISLongyearbyenNorway
  6. 6.CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto (CIBIO/UP)/InBio Laboratório AssociadoVairãoPortugal
  7. 7.CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da SaúdeGandra, PRDPortugal

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