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Impact of Counseling Methods on HIV Retesting Uptake in At-Risk Individuals: A Randomized Controlled Study

  • Nicolas SalvadoriEmail author
  • Luc Decker
  • Nicole Ngo-Giang-Huong
  • Jean-Yves Mary
  • Sylvie Chevret
  • Surachet Arunothong
  • Pierrick Adam
  • Woottichai Khamduang
  • Tanawan Samleerat
  • Prapan Luangsook
  • Visitsak Suksa-ardphasu
  • Jullapong Achalapong
  • Christine Rouzioux
  • Wasna Sirirungsi
  • Gonzague Jourdain
Original Paper
  • 18 Downloads

Abstract

Systematic face-to-face pre-HIV test counseling is costly and may discourage clients to present for regular testing. In a randomized, controlled, non-inferiority trial conducted in four facilities providing free-of-charge anonymous HIV testing in Thailand, participants received either: standard counseling according to national guidelines (reference); computer-assisted counseling: interactive counseling on a tablet computer followed by an invitation to ask questions to the counselor; or on-demand counseling: invitation to ask questions to the counselor. Primary endpoint was a HIV retest within 7 months after enrolment visit. Following the planned interim analysis, on-demand counseling was discontinued for futility. In the final analysis in 1036 HIV-uninfected at-risk participants, computer-assisted counseling was non-inferior to standard counseling and had similar acceptability and improvements in HIV knowledge and sexual risk behaviors; however, it significantly reduced the time spent by counselors on counseling. Implementation of pre-HIV test computer-assisted counseling may ease the burden on staff involved in HIV testing.

Keywords

Counseling Computer Prevention Testing Retesting 

Notes

Acknowledgements

The Napneung project was supported by a grant from Expertise France through the 5% Initiative program (14SANIN204). We thank the members of the Advisory Committee: Sumet Ongwandee, Sombat Thanprasertsuk and Nakorn Premsri (Department of Diseases Control, Ministry of Public Health, Nonthaburi, Thailand), Suchada Chaivoot (National Health Security Office, Nonthaburi, Thailand), Mukta Sharma (World Health Organization, Thailand Country Office, Nonthaburi, Thailand), Chutima Jaruwat and Withun Wongthip (Provincial Public Health Office, Chiang Mai, Thailand), Eric Fleutelot (French Embassy to Thailand, Bangkok, Thailand), Pongthorn Chanlearn (M-Plus, Chiang Mai, Thailand), Ratchadet Reaukhamfu (Caremat, Chiang Mai, Thailand), Bram Press and Namisi Jate (MAP Foundation, Chiang Mai, Thailand), Boonnium Wongjaikham (Thai AIDS Treatment Action Group, Chiang Mai, Thailand), Thitipong Sangyoung (Thai Drug Users’ Network, Chiang Mai, Thailand), Monthira Metha (Fah Mai Clinic, Chiang Mai, Thailand) and Maleerat Vandriesten (Empower, Chiang Mai, Thailand). We also thank all Napneung partners, in particular: ACCESS, CAREMAT, EMPOWER, MAP Foundation, M-Plus, Namklong Colorful, PIMAN Center, PLAN International, Thai AIDS Treatment Action Group and Thai Drug Users' Network; Chiangrai Prachanukroh Hospital, Nakornping Hospital, Sanpatong Hospital, Sarapee Hospital and STIs Clinic of the Office of Disease Prevention and Control Region 1; Chiang Rai Rajabhat University and Mae Fah Luang University; Provincial Public Health Offices; and Department of Disease Control, Thai Ministry of Public Health. We also thank all members of the Napneung project team: Giuliana Zegarra, Paporn Mongkolwat, Prueksalada Khiaokham, Suphakrit Jitrarat and Wanlee Kongnim (project coordination); Ampika Kaewbundit, Areerat Kongphonoi, Chutharat Kasemrat, Duanpen Panyasak, Jiraporn Khamkon, Kanyanee Preechapongmit, Krisana Suphayos, Laddawan Laomanit, Nantawan Wangsaeng, Nilawan Chetacha, Ninutcha Paengsai, Panaddar Phutthakham, Paporn Mongkolwat, Phornphimon Moolnoi, Prapan Luangsook, Subenya Natthanaboon, Tanawan Samleerat, Thipsuda Krueyot, Tiwacha Thimakam, Wanlee Kongnim, Warunee Khamjakkaew, Warunee Srisuk and Woottichai Khamduang (testing and counseling); Boonnium Wongjaikham, Chalathon Jantarapanya, Chittiwa Phumsawai, Jamreon Teeravittayakul, Kanjana Saengkham, Malee Kaewprom, Monthira Metha, Nipa Chomphupa, Prapatsorn Chaisopa, Ratchadet Reaukhamfu, Rodjana Yeepua, Saidao Sanko, Sirintorn Juntong, Sompol Punyasriwichai, Supaluck Nammuang, Thitipong Sangyoung and Wipawan Wongsawasdi (PHPT Community Advisory Board in Chiang Mai); Akrkapong Preechapongmit, Anupab Jampatong, Anyamanee Khattiya, Apirak Jittarat, Areerat Kongponoi, Bancha Kumsiri, Boonrod Suwanpa, Chalita Sakrew, Chopet Nobpharat, Daoruang Sangchan, Daranrat Nuntasonbut, Dawaree Tongcheepcha, Dumrongdech Reunsung, Ekapan Chaiwangras, Jedsada Srijanta, Jinjutha Darasilp, Jirayut Sitasoy, Kajorndej Panichadul, Kajorndej Surapanichadul, Kamolpop Moungtanee, Kamonporn Preechapongmit, Kanok Fuslin, Kanyanee Kaewmamueng, Khwanchanok Saenkriang, Kitipong Daenpen, Kittikun Jantaracha, Kritsana Suphayos, Kulnaree Klomkaew, Kulthida Mueangchanta, Lukkana Sitiritkawin, Maliwan Budsuwan, Manthana Nunta, Mathurada Kanthalee, Metinee Khamwiang, Nattachai Kumket, Nattarika Prommatiam, Natthaporn Chinda, Nawakhun Prungrathanasen, Nonthacha Yodying, Nutnicha Parjarnthit, Paradee Anantakul, Parit Maimun, Pawita Tuithemwong, Phanusporn Moonnoo, Phetay Sakbunyuen, Pilaiwan Yodprasert, Pimwaree Jaiai, Pongpak Sananta, Pornpavee Saleesongsom, Pranee Srikampan, Prapatsorn Alongkornpradub, Ramida Burapa, Ramida Burapa, Rattanai Soparat, Ruekdee Kaewmuangma, Rutchawat Fakkaew, Sangdao Somsri, Saowalak Panyawong, Sarawin Phunyim, Sedtawut Kunnakulsoontorn, Sunirat Manemaung, Sunun Manowan, Supakit Anantakul, Supakorn Tulapong, Supanut Krittitasema, Supawadee Pongprapass, Suphakrit Jitrarat, Suporn Watanaporn, Sureepon Pratumma, Sutikarn Jarenjai, Suttipong Kawilapat, Tanakorn Khamwiang, Tanongsak Suriyakaew, Thanapol Wongkhamnan, Thanyalark Seeti, Theerapong Pinta, Thitipong Luecha, Tidarat Peungtonang, Torraporn Maneerat, Tunya Boonruean, Unyamanee Chantra, Visaka Ruankaew, Wachirapong Teerasawatt, Warakon Aranpitak, Warintorn Fakkaew, Warunee Srisuk, Wasana Chaiwong, Wasinee Poonpon, Watchara Kunthanang, Woottichai Sriwichai, Woranet Wangkhummuen, Woraphan Doungtip, Yatika Theptanee, Yokfah Meena, Yudtana Panyawong, Yupin Buain, Yuthana and Yuthaphom Hongsorn (outreach); Niphatta Mungkhala, Pongsak Pirom and Sakawrut Jitharidkul (hotline); Pra-ornsuda Sukrakanchana, Rukchanok Peongjakta and Suwalai Chalermpantmetagul (monitoring); Ampika Kaewbundit, Chutharat Kasemrat, Jiraporn Khamkon, Jutatip Kaewmalee, Laddawan Laomanit, Nantawan Wangsaeng, Patcharida Insee, Phornphimon Moolnoi, Pimpinun Punyathi, Rumpaiphorn Saisom and Thamonphat Phitak (laboratory); Aye Min Latt, Hark Murng, Naruporn Rawanchaikul and Sineenart Nupradit (translation); Kanchana Than-in-at, Marin Inta, Natthanidnan Sricharoen, Nirattiya Jaisieng, Ratchapat Jitharidkul, Sanuphong Chailoet and Wasan Wongwai (Data Center); Pongsak Pirom and Sakawrut Jitharidkul (administration); Ludovic Barra, Caroline Huron, Claire Le Moigne, Nitima Chaiboonruang, Thanchanok Sriwised, Thibaut Vallet, Tidarat Tritungtrakul (finance). Last but not least, we thank all study participants.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study protocol was reviewed and approved by the ethics committees of the Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, and Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand. An Advisory Committee reviewed annually the study progress as well as the interim analysis results of the counseling study.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Supplementary material

10461_2019_2695_MOESM1_ESM.docx (41 kb)
Supplementary material 1 (DOCX 41 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Nicolas Salvadori
    • 1
    • 2
    Email author
  • Luc Decker
    • 1
    • 2
  • Nicole Ngo-Giang-Huong
    • 1
    • 2
    • 3
  • Jean-Yves Mary
    • 4
  • Sylvie Chevret
    • 4
  • Surachet Arunothong
    • 5
  • Pierrick Adam
    • 1
    • 2
  • Woottichai Khamduang
    • 2
  • Tanawan Samleerat
    • 2
  • Prapan Luangsook
    • 2
  • Visitsak Suksa-ardphasu
    • 2
  • Jullapong Achalapong
    • 6
  • Christine Rouzioux
    • 7
  • Wasna Sirirungsi
    • 2
  • Gonzague Jourdain
    • 1
    • 2
    • 3
  1. 1.Institut de recherche pour le développement (IRD)PHPTChiang MaiThailand
  2. 2.Faculty of Associated Medical SciencesChiang Mai UniversityChiang MaiThailand
  3. 3.Department of Immunology and Infectious DiseasesHarvard T.H. Chan School of Public HealthBostonUSA
  4. 4.INSERM U1153 Team ECSTRA, Université Paris Diderot-Paris 7, Hôpital Saint-LouisParisFrance
  5. 5.Department of Disease ControlMinistry of Public HealthChiang MaiThailand
  6. 6.Chiangrai Prachanukroh HospitalChiang RaiThailand
  7. 7.Laboratoire de Virologie - EA 3620, Université Paris Descartes, Hôpital NeckerParisFrance

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