The relationship of spleen stiffness value measured by shear wave elastography with age, gender, and spleen size in healthy volunteers

  • Eda AlbayrakEmail author
  • Sadık Server
Original Article



The aim of this study is to evaluate spleen stiffness values with shear wave elastography (SWE) quantitatively in healthy adults and investigate the relationship of spleen stiffness with age, gender, and spleen size.


This study included 65 healthy individuals. Spleen stiffness measurement was obtained with 2 dimensional (2-D) SWE method from the middle portion of spleen and calculated in kilopascals by taking the average of three valid measurements. Longitudinal and transverse spleen sizes were measured. The relationship of spleen stiffness with age, gender, and spleen size was investigated. The association between spleen size and age and gender was also evaluated.


The mean spleen stiffness value was 13.82 ± 2.91 kPa, and the spleen stiffness was not affected by age, gender, or spleen size. Longitudinal spleen size was significantly lower in females than that in males. Moreover, there was a significant negative correlation between longitudinal spleen size and age (r = 0.247, p = 0.048).


Spleen stiffness can be quantitatively measured by 2-D SWE, and the spleen stiffness is not affected by age, gender, and spleen size. The values obtained in this study can be used as normal base values in examination of different spleen pathologies.


Spleen Shear wave elastography Ultrasonography 


Compliance with ethical standards

Conflict of interest

Eda Albayrak, Sadık Server declare that they have no conflict of interest.

Ethical statement

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent was obtained from all patients for being included in the study.


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Copyright information

© The Japan Society of Ultrasonics in Medicine 2019

Authors and Affiliations

  1. 1.Department of Radiology, Medical FacultyGaziosmanpasa UniversityTokatTurkey
  2. 2.Department of Radiology, Medical Faculty, Şişli Florence Nightingale HospitalIstanbul Bilim UniversityIstanbulTurkey

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