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Antibiotics and Resistance Genes in Awash River Basin, Ethiopia

  • Alemayehu Adugna Ergie
  • Yifei Leng
  • Jun WangEmail author
Original Contribution
  • 3 Downloads

Abstract

Among contaminants of emerging concern in the environment, a growing attention has been given to antibiotics and antibiotic-resistant genes (ARGs) due to the rise in their usage and potential ecotoxicological and public health effect. However, the occurrence of these contaminants in the environment is little investigated in developing countries particularly in sub-Saharan regions. In this study, the occurrence of three groups of antimicrobials including tetracycline, sulfonamides and fluoroquinolone, and their corresponding ARGs were investigated in the sediments of Awash River Basin, Ethiopia. Out of twelve studied compounds, sulfadiazine and enrofloxacin showed the highest and lowest detection frequency, respectively. Polymerase chain reaction (PCR) analysis revealed that tetA and tetB occurred in all the samples. The relative abundance of the resistant genes was in the following order: tetA > tetB > sul2 > sul1. Redundancy analysis result indicated that some sediment characteristics were found to have influence on the distribution sul1-resistant gene.

Keywords

Ethiopia Sediment Antibiotics Antibiotic-resistant gene Awash River Basin 

Notes

Acknowledgments

This work was financially supported by Funding project of Sino-Africa Joint Research Center, Chinese Academy of Sciences (Y623321K01), National Key Research and Development Program of China, grant number (2018YFD0900604), and Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme (2018).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

10393_2019_1431_MOESM1_ESM.doc (170 kb)
Supplementary material 1 (DOC 169 kb)

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Copyright information

© EcoHealth Alliance 2019

Authors and Affiliations

  1. 1.Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical GardenChinese Academy of SciencesWuhanChina
  2. 2.College of Marine SciencesSouth China Agricultural UniversityGuangzhouChina
  3. 3.Sino-Africa Joint Research CenterChinese Academy of SciencesWuhanChina
  4. 4.University of Chinese Academy of SciencesBeijingChina

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