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Journal of Public Health

, Volume 26, Issue 5, pp 595–603 | Cite as

Hepatitis B virus infection in the Democratic Republic of Congo: a systematic review of prevalence studies (2000–2016)

  • Tony Akilimali Shindano
  • Jeff Maotela Kabinda
  • Patrick Mitashi
  • Yves Horsmans
Review Article
  • 50 Downloads

Abstract

Aims

The Democratic Republic of Congo (DRC) is a country with a high endemicity of hepatitis B virus (HBV) even if no national survey of prevalence has been performed. Data are based on extrapolations or limited studies. This review aimed to summarize all information about HBV infection in DRC during the period 2000–2016 to provide refined estimates and contribute to a better knowledge of its epidemiology.

Subject and methods

We conducted a systematic search in electronic databases of all prevalence studies published between January 1st, 2000 and September 30th, 2016. Additional data from manual search or gray literature were also considered. We included only moderate or high quality studies using the JBI’ tools for qualitative evaluation of researches. HBsAg prevalence was estimated at 95% confidence interval (CI) as result of simple pooling analysis.

Results

Twenty-eight studies were included with data providing from 154,926 subjects: in the majority of these studies (18 out of 28), results were obtained from blood donors. The estimated HBsAg prevalence was 4.9% (95% CI 4.2–5.0). The prevalence was estimated at 5.0% (95% CI 4.9–5.1) in blood donors and at 5.0% (95% CI 3.0–5.9) in pregnant women.

Conclusion

This review suggests that DRC is a country characterized by an intermediate level of HBV infection endemicity rate. It remains however an important public health problem and efforts should continue in prevention and in policy to control this viral disease.

Keywords

Hepatitis B virus Prevalence DRC Review 

Notes

Acknowledgements

The authors are grateful to Professor Béatrice Perrenoud for critical reading.

Compliance with ethical standards

Conflict of interest

Authors have no financial or any potential conflicts of interest to declare.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Université Catholique de Bukavu (UCB), Faculté de MédecineBukavuDemocratic Republic of the Congo
  2. 2.Cliniques Universitaires Saint-LucUniversité Catholique de Louvain (UCL)BrusselsBelgium
  3. 3.Department of Internal MedicineUniversité Catholique de BukavuBukavuDemocratic Republic of the Congo
  4. 4.Centre de Connaissances en Santé au Congo (CCSC)KinshasaDemocratic Republic of the Congo
  5. 5.Université de Kinshasa (UNIKIN), Faculté de MédecineKinshasaDemocratic Republic of the Congo

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