Predictors of vitamin D supplementation amongst infants in Ireland throughout the first year of life
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To investigate predictors of compliance with the recommendation that all infants in Ireland are supplemented daily from birth to 12 months of age with 5 μg of vitamin D.
Subjects and methods
A prospective observational study was conducted. Self-complete questionnaires recorded socio-demographic characteristics, health behaviours and supplementation practices for 158 mother-infant dyads at 4, 9 and 12 months post-partum. A 2-day food diary was also obtained on 12-month-old infants to examine the contribution of diet to vitamin D intakes.
At 4, 9 and 12 months of age, 57.6% (n = 91), 34.2% (n = 54) and 23.4% (n = 37) of infants, respectively, were supplemented as recommended. In multivariate analyses, receiving supplementation advice from health professionals in the early post-partum period was the most significant predictor of correctly supplementing 4-month-old [p < 0.01; odds ratio, OR: 61.94 (95% confidence interval, CI: 11.53–332.83)], 9-month-old [p < 0.01, OR: 10.30 (95% CI: 2.29–46.27)] and 12-month-old [p = 0.04, OR: 3.85 (95% CI: 1.05–14.08)] infants. Amongst 12 month olds, mean intakes from diet and supplementation combined (7.6 ± 4.7 μg/day) were suboptimal.
Suboptimal vitamin D supplementation practices were evident throughout infancy. Dietary intakes of vitamin D did not compensate for suboptimal supplementation practices. Supplementation practices may improve if health professionals advocate safe supplementation during routine infant health checks.
KeywordsVitamin D supplementation Infancy Supplementation policy Infant bone health Non-compliance
The authors wish to acknowledge the mothers who participated in this study; their time was greatly appreciated.
The lead author was funded by a Dublin Institute of Technology Fiosraigh Scholarship. This scholarship was 50% funded by the Dublin Institute of Technology and 50% funded by Danone Nutricia Early Life Nutrition.
Compliance with ethical standards
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committees and with the 1964 Helsinki Declaration and its later amendments.
Informed consent was obtained from all individual participants included in the study.
Conflict of interest
The authors have no conflict of interest to declare.
- Abraham C, Sheeran P (2005) The health belief model. In: Conner M, Norman P (eds) Predicting health behaviour. Open University Press. Berkshire, England, pp 28–80Google Scholar
- Arditi C, Rège-Walther M, Wyatt JC, Durieux P, Burnand B (2012) Computer-generated reminders delivered on paper to healthcare professionals; effects on professional practice and healthcare outcomes. Cochrane Data Syst Rev. https://doi.org/10.1002/14651858.CD001175.pub3
- Food Safety Authority of Ireland (2007) Recommendations for a national policy on vitamin D supplementation for infants in Ireland. Author, DublinGoogle Scholar
- Food Safety Authority of Ireland (2011) Scientific recommendations for a national infant feeding policy, 2nd edn. Author, DublinGoogle Scholar
- Gallo S, Vanstone CA, Weiler HA (2012) Normative data for bone mass in healthy term infants from birth to 1 year of age. J Osteoporos; ID 672403Google Scholar
- Gandhi TK, Sequist TD, Poon EG, Karson AS, Murff H, Fairchild DG, Kuperman GJ, Bates DW (2003) Primary care clinician attitudes towards electronic clinical reminders and clinical practice guidelines. AMIA Annu Symp Proc 848Google Scholar
- Health Service Executive (2010) Policy on vitamin D supplementation for infants in Ireland, 2010. Available from: https://www.hse.ie/eng/health/child/vitaminD/Vitamin%20D%20Policy.pdf. Accessed 17 July 2015
- Health Service Executive (2017) A guide to your child’s growth and development. Available from: http://www.hse.ie/eng/health/child/cfyb/2-5yrs/growthdevelopment/. Accessed 10 December 2017
- Institute of Medicine (2010) Dietary reference intakes for calcium and vitamin D, 1st edn. The National Academies Press, Washington DCGoogle Scholar
- Irish Universities Nutrition Alliance (2012) National pre-School Nutrition Survey: summary report. Author, CorkGoogle Scholar
- Patience S (2015) Promoting vitamin D uptake in infants and children. BJM 23:10S–13SGoogle Scholar
- Sequist TD, Gandhi TK, Karson AS, Fiskio JM, Bugbee D, Sperling M, Cook EF, Orav EJ, Fairchild DG, Bates DW (2005) A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary artery disease. J Am Med Inform Assoc 12:431–437CrossRefPubMedPubMedCentralGoogle Scholar
- Touskova T, Vytrisalova M, Palicka V, Hendrychova T, Fuska L, Holcova R, Konopacova J, Kubena AA (2015) Drug holidays: the most frequent type of non-compliance with calcium plus vitamin D supplementation in persistent patients with osteoporosis. Patient Prefer Adherence 9:1771–1779PubMedPubMedCentralGoogle Scholar