Journal of Public Health

, Volume 25, Issue 4, pp 371–377 | Cite as

Factors associated with health-related quality of life among children with cancer from the standpoint of patients and caregivers

  • Tamires Vieira CarneiroEmail author
  • Isabella Lima Arrais Ribeiro
  • Caroline Vieira Alves
  • Paulo Rogério Ferreti Bonan
  • Eufrásio de Andrade Lima Neto
  • Ana Maria Gondim Valença
Original Article



The quality of life for childhood cancer patients is impaired by this disease and its treatment. Knowing the factors that contribute most to this framework allows identifying the greatest needs, subsidized preventive strategies. The objective of the study was assessing the factors associated with health-related quality of life among children with cancer from the standpoint of patients and caregivers.


A cross-sectional study was conducted with sample consisted of 71 patients between the ages of 5 and 18 as well as their caregivers. Two forms (clinical examination and interview) from the National Oral Health Survey, the Modified Oral Assessment Guide and the Pediatric Quality of Life Inventory (PedsQLTM) version 3.0 were used as data collection instruments.


From the standpoint of the caregivers, having fewer cognitive difficulties (OR = 0.92), fewer pain symptoms and hurt (OR = 0.94) and lower procedure anxiety (OR = 0.93) were associated with higher quality of life scores; by contrast, being female (OR = 9.49), the number of household members (OR = 1.94) and smiling with embarrassment (OR = 13.82) were associated with lower quality of life score. From the standpoint of patients, having fewer cognitive difficulties (OR = 0.94) and positive perception of physical appearance (OR = 0.94) were associated with higher quality of life scores; by contrast, smiling with embarrassment (OR = 11.56) and toothaches (OR = 7.37) were associated with lower quality of life score.


The patient and caregiver symptom reports yielded distinct results, although cognitive difficulties and smiling with embarrassment were significantly associated with impaired quality of life on both types of reports.


Quality of life Neoplasms Pediatric dentistry Child Adolescent 



Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes), Brazil

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Tamires Vieira Carneiro
    • 1
    Email author
  • Isabella Lima Arrais Ribeiro
    • 1
  • Caroline Vieira Alves
    • 1
  • Paulo Rogério Ferreti Bonan
    • 1
  • Eufrásio de Andrade Lima Neto
    • 1
  • Ana Maria Gondim Valença
    • 1
  1. 1.Federal University of Paraíba (Universidade Federal da Paraíba - UFPB)João PessoaBrazil

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