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European Surgery

, Volume 51, Issue 6, pp 325–332 | Cite as

Quantification of the effects of coffee on postoperative ileus after laparoscopic ventral rectopexy: a randomized controlled trial

  • Kentaro HayashiEmail author
  • Akira Tsunoda
  • Atsushi Shiraishi
  • Hiroshi Kusanagi
original article

Summary

Background

Coffee consumption positively affects intestinal function following abdominal surgery with bowel resection. This study aimed to quantify the effect of coffee on intestinal activity after laparoscopic ventral rectopexy (LVR).

Methods

We conducted a single-center, open-labeled, randomized controlled trial from 2014 to 2016 (UMIN-CTR, UMIN000024908). Patients who had undergone scheduled LVR for rectal intussusception or external rectal prolapse were randomly assigned to a coffee group or a water group (23 per group) and asked to drink 100 ml of either coffee or water after the procedure. Each participant was orally administered a radiopaque marker capsule the morning after surgery, and abdominal radiographs were obtained daily. The primary outcome was the total number of evacuated radiopaque markers 26 h after administration. Secondary outcomes included time to first flatus and defecation and results of segmental transit analysis of the markers on radiographs.

Results

The mean number of evacuated radiopaque markers 26 h after administration in the coffee group was significantly higher than that in the water group (1 [range, 0–6] vs. 0 [range, 0–0]; p = 0.04), however, the mean time (hours) to first defecation (55.1 [range, 19.1–114.0] vs. 69.7 [range, 20.7–141.6]; p = 0.13) or time (hours) to first flatus (9.3 [range, 0.5–47.1] vs. 12.6 [range, 1.1–46.1]; p = 0.35) was not significant.

Conclusion

Coffee consumption accelerates bowel movements, but its clinical effect after LVR is also small. Further studies about the indication of coffee for the type of surgery or the optimal amount of coffee consumption are warranted.

Keywords

Coffee Enhanced recovery after surgery Ileus Postoperative care Postoperative complications 

Notes

Acknowledgements

The authors thank Yoshiyuki Kiyasu, Yuma Yagi, Tomonori Ohta, and Tomoko Takahashi for assisting with operations and perioperative care. We also thank all other staff involved in this study.

Compliance with ethical guidelines

Conflict of interest

K. Hayashi, A. Tsunoda, A. Shiraishi, and H. Kusanagi declare that they have no competing interests.

Ethical standards

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

References

  1. 1.
    Venara A, Neunlist M, Slim K, Barbieux J, Colas PA, Hamy A, et al. Postoperative ileus: Pathophysiology, incidence, and prevention. J Visc Surg. 2016;153(6):439–46.CrossRefGoogle Scholar
  2. 2.
    Brown SR, Cann PA, Read NW. Effect of coffee on distal colon function. Gut. 1990;31(4):450–3.CrossRefGoogle Scholar
  3. 3.
    Rao SS, Welcher K, Zimmerman B, Stumbo P. Is coffee a colonic stimulant? Eur J Gastroenterol Hepatol. 1998;10(2):113–8.CrossRefGoogle Scholar
  4. 4.
    Müller SA, Rahbari NN, Schneider F, Warschkow R, Simon T, von Frankenberg M, et al. Randomized clinical trial on the effect of coffee on postoperative ileus following elective colectomy. Br J Surg. 2012;99(11):1530–8.CrossRefGoogle Scholar
  5. 5.
    Dulskas A, Klimovskij M, Vitkauskiene M, Samalavicius NE. Effect of coffee on the length of postoperative ileus after elective laparoscopic left-sided colectomy: a randomized, prospective single-center study. Dis Colon Rectum. 2015;58(11):1064–9.CrossRefGoogle Scholar
  6. 6.
    Piric M, Pasic F, Rifatbegovic Z, Konjic F. The effects of drinking coffee while recovering from colon and rectal resection surgery. Med Arch. 2015;69(6):357–61.CrossRefGoogle Scholar
  7. 7.
    Güngördük K, Özdemir İA, Güngördük Ö, Gülseren V, Gokçü M, Sancı M. Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: a randomized controlled trial. Am J Obstet Gynecol. 2017;216(2):145.e1.CrossRefGoogle Scholar
  8. 8.
    D’Hoore A, Cadoni R, Penninckx F. Long-term outcome of laparoscopic ventral rectopexy for total rectal prolapse. Br J Surg. 2004;91(11):1500–5.CrossRefGoogle Scholar
  9. 9.
    Fearon KC, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CH, Lassen K, et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr. 2005;24(3):466–77.CrossRefGoogle Scholar
  10. 10.
    Kehlet H, Wilmore DW. Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg. 2008;248(2):189–98.CrossRefGoogle Scholar
  11. 11.
    Hinton JM, Lennard-Jones JE, Young AC. A new method for studying gut transit times using radioopaque markers. Gut. 1969;10(10):842–7.CrossRefGoogle Scholar
  12. 12.
    Arhan P, Devroede G, Jehannin B, Lanza M, Faverdin C, Dornic C, et al. Segmental colonic transit time. Dis Colon Rectum. 1981;24(8):625–9.CrossRefGoogle Scholar
  13. 13.
    Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 2013;48(3):452–8.CrossRefGoogle Scholar
  14. 14.
    Boekema PJ, Lo B, Samsom M, Akkermans LM, Smout AJ. The effect of coffee on gastric emptying and oro-caecal transit time. Eur J Clin Invest. 2000;30(2):129–34.CrossRefGoogle Scholar
  15. 15.
    Sloots CE, Felt-Bersma RJ, West RL, Kuipers EJ. Stimulation of defecation: effects of coffee use and nicotine on rectal tone and visceral sensitivity. Scand J Gastroenterol. 2005;40(7):808–13.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Gastroenterological SurgeryKameda Medical CenterKamogawa CityJapan
  2. 2.Emergency and Trauma CenterKameda Medical CenterKamogawa CityJapan

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