Advertisement

A 20-year evolution of cardiac performance in microgravity in a male astronaut

This is a preview of subscription content, log in to check access.

Access options

Buy single article

Instant unlimited access to the full article PDF.

US$ 39.95

Price includes VAT for USA

Subscribe to journal

Immediate online access to all issues from 2019. Subscription will auto renew annually.

US$ 199

This is the net price. Taxes to be calculated in checkout.

Fig. 1

Data availability

The datasets generated during and analyzed during the current study are not publicly available due to protect the medical data of the participant but are available from the corresponding author on reasonable request.

References

  1. 1.

    Almeida-Santos MA, Barreto-Filho JA, Oliveira JL, Reis FP, da Cunha Oliveira CC, Sousa AC (2016) Aging, heart rate variability and patterns of autonomic regulation of the heart. Arch Gerontol Geriatr 63:1–8

  2. 2.

    Brandfonbrener M, Landowne M, Shock NW (1955) Changes in cardiac output with age. Circulation 12:557–566

  3. 3.

    Eckberg DL, Diedrich A, Cooke WH, et al (2016) Respiratory modulation of human autonomic function: long-term neuroplasticity in space. J Physiol 594:5629–5646

  4. 4.

    Jones PP, Shapiro LF, Keisling GA, et al (2001) Altered autonomic support of arterial blood pressure with age in healthy men. Circulation 104:2424–2429

  5. 5.

    Kovacs GTA, Shadden M (2017) Analysis of age as a factor in NASA astronaut selection and career landmarks. PLoS ONE 12:e0181381

  6. 6.

    Limper U, Gauger P, Beck P, Krainski F, May F, Beck LE (2014) Interactions of the human cardiopulmonary, hormonal and body fluid systems in parabolic flight. Eur J Appl Physiol 114:1281–1295

  7. 7.

    Perhonen MA, Franco F, Lane LD, et al (2001) Cardiac atrophy after bed rest and spaceflight. J Appl Physiol 91:645–653

  8. 8.

    Prisk GK, Verhaeghe S, Padeken D, Hamacher H, Paiva M (2001) Three-dimensional ballistocardiography and respiratory motion in sustained microgravity. Aviat Space Environ Med 72:1067–1074

  9. 9.

    Rossum AC, Ziegler MG, Meck JV (2001) Effect of spaceflight on cardiovascular responses to upright posture in a 77-year-old astronaut. Am J Cardiol 88:1335–1337

  10. 10.

    Shibao C, Grijalva CG, Raj SR, Biaggioni I, Griffin MR (2007) Orthostatic hypotension-related hospitalizations in the United States. Am J Med 120:975–980

Download references

Acknowledgements

This work was supported by the Grants 50WB1255 and 50WB1517 of the German Federal Ministry for Economic Affairs and Energy. We are grateful to the German Aerospace Center for providing the flight opportunity during the 22nd DLR Parabolic Flight Campaign. We are also thankful to Wolfram Sies for his technical support and to the appointees of NOVESPACE for all their skillful help.

Author information

UL, SM, GKP, AG, PFM, PG, LEJB, HWS contributed substantially to conception and design of the study. UL, SM, GKP, AG, PFM, PG, HWS performed data acquisition. UL, SM, JT, KH, FH, AG performed statistical data analysis. UL, SM, JT, GKP, KH, FH, AG, PFM, PG, LEJB, HWS, BDL, JJ contributed to interpretation of the data of the work. UL and JJ wrote the first draft of the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.

Correspondence to Ulrich Limper.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Electronic supplementary material

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Limper, U., Moestl, S., Tank, J. et al. A 20-year evolution of cardiac performance in microgravity in a male astronaut. Clin Auton Res (2020) doi:10.1007/s10286-019-00657-1

Download citation