Relapsing paralytic ileus in multiple sclerosis requiring surgery: a video case report
Autonomic dysfunction has been previously described in patients with multiple sclerosis (MS), with prominent involvement of the cardiovascular, urinary, and gastrointestinal branches of the autonomic nervous system (ANS) [1, 2, 3]. Gastrointestinal dysfunction is particularly remarkable in these patients, with both constipation and fecal incontinence being its most prevalent manifestations [4, 5]. Moreover, correlations between disability, disease duration, prevalence, and severity of bowel symptoms have been drawn . Recently, acute manifestations of gastrointestinal dysfunction, ranging from acute dysphagia to gastroparesis to acute paralytic ileus have been increasingly recognized and incorporated into patients’ assessments .
We had the chance to witness the case of a 44-year-old woman with a clinically stable relapsing–remitting form of MS, a mild functional disability (EDSS 2.0 defined by relevant fatigue), treated with interferon beta-1a 44 mcg (Rebif®) for...
KeywordsMultiple sclerosis Autonomic dysfunction Dysautonomia Autonomic nervous system Paralytic ileus Sub-obstructive ileus Enteric nervous system