Relapsing paralytic ileus in multiple sclerosis requiring surgery: a video case report

  • G. Chiaro
  • C. Fratila
  • F. Martig
  • C. Zecca
  • C. GobbiEmail author
Letter to the Editor

Dear Editors,

Autonomic dysfunction has been previously described in patients with multiple sclerosis (MS), with prominent involvement of the cardiovascular, urinary, and gastrointestinal branches of the autonomic nervous system (ANS) [1, 2, 3]. Gastrointestinal dysfunction is particularly remarkable in these patients, with both constipation and fecal incontinence being its most prevalent manifestations [4, 5]. Moreover, correlations between disability, disease duration, prevalence, and severity of bowel symptoms have been drawn [6]. Recently, acute manifestations of gastrointestinal dysfunction, ranging from acute dysphagia to gastroparesis to acute paralytic ileus have been increasingly recognized and incorporated into patients’ assessments [4].

We had the chance to witness the case of a 44-year-old woman with a clinically stable relapsing–remitting form of MS, a mild functional disability (EDSS 2.0 defined by relevant fatigue), treated with interferon beta-1a 44 mcg (Rebif®) for...


Multiple sclerosis Autonomic dysfunction Dysautonomia Autonomic nervous system Paralytic ileus Sub-obstructive ileus Enteric nervous system 

Supplementary material

10286_2018_573_MOESM1_ESM.mp4 (86.6 mb)
Supplementary material 1 (MP4 88706 kb) A short intra-surgical clip showing complete absence of small bowel peristaltic activity


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Neurocenter of Southern SwitzerlandCivic Hospital of LuganoLuganoSwitzerland
  2. 2.Department of Biomedical and Neuromotor SciencesUniversity of BolognaBolognaItaly
  3. 3.Department of SurgeryCivic Hospital of LuganoLuganoSwitzerland

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