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Odontology

, Volume 107, Issue 4, pp 530–535 | Cite as

Self-reported periodontitis and migraine: results from a multicenter, cross-sectional survey in Spain

  • Yago LeiraEmail author
  • Patricia Pozo-Rosich
  • Marta Torres-Ferrús
  • Marco Orlandi
  • José Miguel Láinez
  • Luis Carlos Álvaro
  • María José Monzón
  • Ángel Guerrero
  • David García-Azorín
  • Roberto Belvís
  • Carmen González-Oria
  • Ana Beatriz Gago-Veiga
  • Germán Latorre
  • Sonia Santos
  • María Luz Cuadrado
  • Juan Blanco
  • Rogelio Leira
  • Francesco D’Aiuto
Original Article

Abstract

The aim of this study was to evaluate self-reported periodontitis (PD) prevalence in migraineurs as well as to investigate the association between both diseases. A cross-sectional survey was carried out including patients diagnosed with migraine attending 12 Spanish Headache Units. We determined diagnosis of PD administering a validated self-reported questionnaire. Socio-demographic, clinical and medical information, comorbidities, daily habits, migraine characteristics and medication were collected using a questionnaire. Of the 651 consecutive migraineurs included in the study, 393 suffered from chronic migraine (CM). Self-reported PD was detected in 327 patients with migraine (50.2%). Migraineurs with self-reported PD were significantly older and had a previous history of fibromyalgia, stress, anxiety, depression, and allodynia (all P < 0.001). Additionally, this group of patients consumed more topiramate (P = 0.008) and simple analgesics (P < 0.001) than patients with migraine and without self-reported PD. Also, they were less active physically and belonged to a low education level (both P < 0.001). Prevalence of self-reported PD was significantly higher in chronic migraineurs compared to those diagnosed with episodic migraine (EM) (53.9% vs. 44.6%, P = 0.019). Logistic regression analyses showed that self-reported PD was associated with CM (OR 1.456; 95% CI 1.062–1.997, P = 0.020). However, after adjusting for significant confounders, the association was attenuated (OR 1.100; 95% CI 0.784–1.543, P = 0.581). We concluded that self-reported PD was significantly more frequent in CM compared to EM. Self-reported PD was associated with the presence of CM, although some comorbidities shared by both diseases could have an effect on this association.

Keywords

Periodontitis Headache Prevalence Chronic migraine Epidemiology 

Notes

Acknowledgements

Yago Leira holds a Senior Clinical Research Fellowship supported by the UCL Biomedical Research Centre.

Funding

This study was partially supported by grants from the Spanish Ministry of Economy and Competitiveness—Institute of Health Carlos III (PI15/01578). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all the individual participants included in the study.

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Copyright information

© The Society of The Nippon Dental University 2019

Authors and Affiliations

  • Yago Leira
    • 1
    • 2
    Email author
  • Patricia Pozo-Rosich
    • 3
    • 4
  • Marta Torres-Ferrús
    • 3
    • 4
  • Marco Orlandi
    • 1
  • José Miguel Láinez
    • 5
  • Luis Carlos Álvaro
    • 6
  • María José Monzón
    • 7
  • Ángel Guerrero
    • 8
  • David García-Azorín
    • 8
  • Roberto Belvís
    • 9
  • Carmen González-Oria
    • 10
  • Ana Beatriz Gago-Veiga
    • 11
  • Germán Latorre
    • 12
  • Sonia Santos
    • 13
  • María Luz Cuadrado
    • 14
  • Juan Blanco
    • 2
  • Rogelio Leira
    • 15
  • Francesco D’Aiuto
    • 1
  1. 1.Periodontology Unit, UCL Eastman Dental Institute and HospitalUniversity College LondonLondonUK
  2. 2.Periodontology Unit, Faculty of Medicine and OdontologyUniversity of Santiago de Compostela, Medical-Surgical Dentistry (OMEQUI) Research Group, Health Research Institute of Santiago de Compostela (IDIS)Santiago de CompostelaSpain
  3. 3.Headache Unit, Neurology DepartmentVall d’Hebron University HospitalBarcelonaSpain
  4. 4.Headache Research Group, Vall d’Hebron Institute of Research (VHIR)Universitat Autónoma de BarcelonaBarcelonaSpain
  5. 5.Department of Neurology, Hospital Clínico UniversitarioUniversidad Católica de ValenciaValenciaSpain
  6. 6.Hospital Universitario Basurto, Universidad del País Vasco/Euskal Herriko Unibertsitatea EHU/UPVBilbaoSpain
  7. 7.Hospital Universitario Miguel ServetZaragozaSpain
  8. 8.Hospital Clínico Universitario de ValladolidValladolidSpain
  9. 9.Hospital de la Santa Creu i Sant PauBarcelonaSpain
  10. 10.Hospital Universitario Virgen del RocíoSevillaSpain
  11. 11.Hospital Universitario La PrincesaMadridSpain
  12. 12.Hospital Universitario de FuenlabradaMadridSpain
  13. 13.Hospital Clínico Universitario Lozano BlesaZaragozaSpain
  14. 14.Department of Neurology, Headache Unit, Hospital Clínico San Carlos, San Carlos Institute for Health Research (IdISSC)Complutense University of MadridMadridSpain
  15. 15.Department of Neurology, Headache Unit, Hospital Clínico UniversitarioUniversity of Santiago de Compostela, Clinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS)Santiago de CompostelaSpain

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