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Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management

Abstract

The Italian Society of Colorectal Surgery (SICCR) promoted the project reported here, which consists of a Position Statement of Italian colorectal surgeons to address the surgical aspects of inflammatory bowel disease management. Members of the society were invited to express their opinions on several items proposed by the writing committee, based on evidence available in the literature. The results are presented, focusing on relevant points. The present paper is not an alternative to available guidelines; rather, it offers a snapshot of the attitudes of SICCR surgeons about the general principles of surgical treatment of inflammatory bowel disease. The committee was able to identify some points of major disagreement and suggested strategies to improve quality of available data and acceptance of guidelines.

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References

  1. 1.

    Gionchetti P, Dignass A, Danese S, Magro Dias FJ, Rogler G, Lakatos PL, Adamina M, Ardizzone S, Buskens CJ, Sebastian S, Laureti S, Sampietro GM, Vucelic B, van der Woude CJ, Barreiro-de Acosta M, Maaser C, Portela F, Vavricka SR, Gomollón F, ECCO (2017) 3rd European Evidence-based consensus on the diagnosis and management of Crohn's disease 2016: part 2: surgical management and special situations. J Crohn's Colitis 11(2):135–149. https://doi.org/10.1093/ecco-jcc/jjw169

  2. 2.

    Magro F, Gionchetti P, Eliakim R, Ardizzone S, Armuzzi A, Barreiro-de Acosta M, Burisch J, Gecse KB, Hart AL, Hindryckx P, Langner C, Limdi JK, Pellino G, Zagórowicz E, Raine T, Harbord M, Rieder F, [ECCO] ECsaCO (2017) Third European evidence-based consensus on diagnosis and management of ulcerative colitis: part 1: definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders. J Crohn's Colitis 11(6):649–670. https://doi.org/10.1093/ecco-jcc/jjx008

  3. 3.

    Magro F, Peyrin-Biroulet L, Sokol H, Aldeger X, Costa A, Higgins PD, Joyce JC, Katsanos KH, Lopez A, de Xaxars TM, Toader E, Beaugerie L (2014) Extra-intestinal malignancies in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (III). J Crohn's Colitis 8(1):31–44. https://doi.org/10.1016/j.crohns.2013.04.006

  4. 4.

    Øresland T, Bemelman WA, Sampietro GM, Spinelli A, Windsor A, Ferrante M, Marteau P, Zmora O, Kotze PG, Espin-Basany E, Tiret E, Sica G, Panis Y, Faerden AE, Biancone L, Angriman I, Serclova Z, de Buck-van-Overstraeten A, Gionchetti P, Stassen L, Warusavitarne J, Adamina M, Dignass A, Eliakim R, Magro F, D'Hoore A (2015) European evidence based consensus on surgery for ulcerative colitis. J Crohn's Colitis 9(1):4–25. https://doi.org/10.1016/j.crohns.2014.08.012

  5. 5.

    Rieder F, de Bruyn JR, Pham BT, Katsanos K, Annese V, Higgins PD, Magro F, Dotan I (2014) Results of the 4th scientific workshop of the ECCO (group II): markers of intestinal fibrosis in inflammatory bowel disease. J Crohn's Colitis 8(10):1166–1178. https://doi.org/10.1016/j.crohns.2014.03.009

  6. 6.

    Rieder F, Latella G, Magro F, Yuksel ES, Higgins PD, Di Sabatino A, de Bruyn JR, Rimola J, Brito J, Bettenworth D, Van Assche G, Bemelman W, D'Hoore A, Pellino G, Dignass AU (2016) European Crohn's and colitis organisation topical review on prediction, diagnosis and management of fibrostenosing Crohn's disease. J Crohn's Colitis. https://doi.org/10.1093/ecco-jcc/jjw055

  7. 7.

    van der Woude CJ, Ardizzone S, Bengtson MB, Fiorino G, Fraser G, Katsanos K, Kolacek S, Juillerat P, Mulders AG, Pedersen N, Selinger C, Sebastian S, Sturm A, Zelinkova Z, Magro F, (ECCO) ftECsaCO (2014) The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohn's Colitis. https://doi.org/10.1093/ecco-jcc/jju006

  8. 8.

    Brown SR, Fearnhead NS, Faiz OD, Abercrombie JF, Acheson AG, Arnott RG, Clark SK, Clifford S, Davies RJ, Davies MM, Douie WJP, Dunlop MG, Epstein JC, Evans MD, George BD, Guy RJ, Hargest R, Hawthorne AB, Hill J, Hughes GW, Limdi JK, Maxwell-Armstrong CA, O'Connell PR, Pinkney TD, Pipe J, Sagar PM, Singh B, Soop M, Terry H, Torkington J, Verjee A, Walsh CJ, Warusavitarne JH, Williams AB, Williams GL, Wilson RG, Collaboration AISC (2018) The Association of coloproctology of Great Britain and Ireland consensus guidelines in surgery for inflammatory bowel disease. Colorectal Dis 20(Suppl 8):3–117. https://doi.org/10.1111/codi.14448

  9. 9.

    Annese V, Beaugerie L, Egan L, Biancone L, Bolling C, Brandts C, Dierickx D, Dummer R, Fiorino G, Gornet JM, Higgins P, Katsanos KH, Nissen L, Pellino G, Rogler G, Scaldaferri F, Szymanska E, Eliakim R, ECCO (2015) European evidence-based consensus: inflammatory bowel disease and malignancies. J Crohn's Colitis. https://doi.org/10.1093/ecco-jcc/jjv141

  10. 10.

    Annese V, Daperno M, Rutter MD, Amiot A, Bossuyt P, East J, Ferrante M, Goetz M, Katsanos KH, Kiesslich R, Ordas I, Repici A, Rosa B, Sebastian S, Kucharzik T, Eliakim R, ECCO (2013) European evidence based consensus for endoscopy in inflammatory bowel disease. J Crohns Colitis 7(12):982–1018. https://doi.org/10.1016/j.crohns.2013.09.016

  11. 11.

    Gomollón F, Dignass A, Annese V, Tilg H, Van Assche G, Lindsay JO, Peyrin-Biroulet L, Cullen GJ, Daperno M, Kucharzik T, Rieder F, Almer S, Armuzzi A, Harbord M, Langhorst J, Sans M, Chowers Y, Fiorino G, Juillerat P, Mantzaris GJ, Rizzello F, Vavricka S, Gionchetti P, ECCO (2017) 3rd European evidence-based consensus on the diagnosis and management of Crohn's disease 2016: part 1: diagnosis and medical management. J Crohn's Colitis 11(1):3–25. https://doi.org/10.1093/ecco-jcc/jjw168

  12. 12.

    Torres J, Bonovas S, Doherty G, Kucharzik T, Gisbert JP, Raine T, Adamina M, Armuzzi A, Bachmann O, Bager P, Biancone L, Bokemeyer B, Bossuyt P, Burisch J, Collins P, El-Hussuna A, Ellul P, Frei-Lanter C, Furfaro F, Gingert C, Gionchetti P, Gomollon F, González-Lorenzo M, Gordon H, Hlavaty T, Juillerat P, Katsanos K, Kopylov U, Krustins E, Lytras T, Maaser C, Magro F, Marshall JK, Myrelid P, Pellino G, Rosa I, Sabino J, Savarino E, Spinelli A, Stassen L, Uzzan M, Vavricka S, Verstockt B, Warusavitarne J, Zmora O, Fiorino G (2019) ECCO guidelines on therapeutics in Crohn's disease: medical treatment. J Crohn's Colitis. https://doi.org/10.1093/ecco-jcc/jjz180

  13. 13.

    Pellino G, Keller DS, Sampietro GM, Annese V, Carvello M, Celentano V, Coco C, Colombo F, Cracco N, Di Candido F, Franceschi M, Laureti S, Mattioli G, Pio L, Sciaudone G, Sica G, Villanacci V, Zinicola R, Leone S, Danese S, Spinelli A, Delaini G, Selvaggi F, on behalf of The Italian Society of Colorectal Surgery SICCR (2019) Inflammatory bowel disease position statement of the Italian Society of Colorectal Surgery (SICCR): Crohn’s disease. Techs Coloproctol. https://doi.org/10.1007/s10151-019-02145-0

  14. 14.

    Stange EF, Travis SP, Vermeire S, Beglinger C, Kupcinkas L, Geboes K, Barakauskiene A, Villanacci V, Von Herbay A, Warren BF, Gasche C, Tilg H, Schreiber SW, Schölmerich J, Reinisch W, Organisation ECsaC (2006) European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. Gut 55(Suppl 1):i1–i15. https://doi.org/10.1136/gut.2005.081950a

  15. 15.

    Sagar PM, Lewis W, Holdsworth PJ, Johnston D, Mitchell C, MacFie J (1993) Quality of life after restorative proctocolectomy with a pelvic ileal reservoir compares favorably with that of patients with medically treated colitis. Dis Colon Rectum 36(6):584–592. https://doi.org/10.1007/bf02049866

  16. 16.

    Vaizey CJ, Carapeti E, Cahill JA, Kamm MA (1999) Prospective comparison of faecal incontinence grading systems. Gut 44(1):77–80. https://doi.org/10.1136/gut.44.1.77

  17. 17.

    Magro F, Langner C, Driessen A, Ensari A, Geboes K, Mantzaris GJ, Villanacci V, Becheanu G, Borralho Nunes P, Cathomas G, Fries W, Jouret-Mourin A, Mescoli C, de Petris G, Rubio CA, Shepherd NA, Vieth M, Eliakim R, (ESP) ESoP, (ECCO) ECsaCO (2013) European consensus on the histopathology of inflammatory bowel disease. J Crohn's Colitis 7(10):827–851. https://doi.org/10.1016/j.crohns.2013.06.001

  18. 18.

    Santos MPC, Gomes C, Torres J (2018) Familial and ethnic risk in inflammatory bowel disease. Ann Gastroenterol 31(1):14–23. https://doi.org/10.20524/aog.2017.0208

  19. 19.

    Katsanos KH, Torres J, Roda G, Brygo A, Delaporte E, Colombel JF (2015) Review article: non-malignant oral manifestations in inflammatory bowel diseases. Aliment Pharmacol Ther 42(1):40–60. https://doi.org/10.1111/apt.13217

  20. 20.

    Lankarani KB, Sivandzadeh GR, Hassanpour S (2013) Oral manifestation in inflammatory bowel disease: a review. World J Gastroenterol WJG 19(46):8571–8579. https://doi.org/10.3748/wjg.v19.i46.8571

  21. 21.

    Haboubi N (2006) Small bowel inflammation in ulcerative colitis. Colorectal Dis 8(5):373–374. https://doi.org/10.1111/j.1463-1318.2006.01043.x

  22. 22.

    Hamilton MJ, Makrauer FM, Golden K, Wang H, Friedman S, Burakoff RB, Levine JS, Joshi P, Banks PA, Odze RD (2016) Prospective evaluation of terminal ileitis in a surveillance population of patients with ulcerative colitis. Inflamm Bowel Dis 22(10):2448–2455. https://doi.org/10.1097/MIB.0000000000000911

  23. 23.

    Bell AJ, Price AB, Forbes A, Ciclitira PJ, Groves C, Nicholls RJ (2006) Pre-pouch ileitis: a disease of the ileum in ulcerative colitis after restorative proctocolectomy. Colorectal Dis 8(5):402–410. https://doi.org/10.1111/j.1463-1318.2006.00954.x

  24. 24.

    Zinicola R, Nicholls RJ (2004) Restorative proctocolectomy in patients with ulcerative colitis having a recto-vaginal fistula. Colorectal Dis 6(4):261–264. https://doi.org/10.1111/j.1463-1318.2004.00606.x

  25. 25.

    Castiglione F, Mainenti PP, De Palma GD, Testa A, Bucci L, Pesce G, Camera L, Diaferia M, Rea M, Caporaso N, Salvatore M, Rispo A (2013) Noninvasive diagnosis of small bowel Crohn's disease: direct comparison of bowel sonography and magnetic resonance enterography. Inflamm Bowel Dis 19(5):991–998. https://doi.org/10.1097/MIB.0b013e3182802b87

  26. 26.

    Gauci J, Sammut L, Sciberras M, Piscopo N, Micallef K, Cortis K, Ellul P (2018) Small bowel imaging in Crohn's disease patients. Ann Gastroenterol 31(4):395–405. https://doi.org/10.20524/aog.2018.0268

  27. 27.

    Haas K, Rubesova E, Bass D (2016) Role of imaging in the evaluation of inflammatory bowel disease: how much is too much? World J Radiol 8(2):124–131. https://doi.org/10.4329/wjr.v8.i2.124

  28. 28.

    Kopylov U, Yung DE, Engel T, Vijayan S, Har-Noy O, Katz L, Oliva S, Avni T, Battat R, Eliakim R, Ben-Horin S, Koulaouzidis A (2017) Diagnostic yield of capsule endoscopy versus magnetic resonance enterography and small bowel contrast ultrasound in the evaluation of small bowel Crohn's disease: systematic review and meta-analysis. Dig Liver Dis 49(8):854–863. https://doi.org/10.1016/j.dld.2017.04.013

  29. 29.

    Sciaudone G, Pellino G, Guadagni I, Pezzullo A, Selvaggi F (2010) Wireless capsule endoscopy years after Michelassi stricturoplasty for Crohn's disease. Acta Chir Belg 110(2):213–215

  30. 30.

    Lee SS, Kim AY, Yang SK, Chung JW, Kim SY, Park SH, Ha HK (2009) Crohn disease of the small bowel: comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques. Radiology 251(3):751–761. https://doi.org/10.1148/radiol.2513081184

  31. 31.

    Choi M, Lim S, Choi MG, Shim KN, Lee SH (2017) Effectiveness of capsule endoscopy compared with other diagnostic modalities in patients with small bowel Crohn's disease: a meta-analysis. Gut Liver 11(1):62–72. https://doi.org/10.5009/gnl16015

  32. 32.

    Catalano OA, Gee MS, Nicolai E, Selvaggi F, Pellino G, Cuocolo A, Luongo A, Catalano M, Rosen BR, Gervais D, Vangel MG, Soricelli A, Salvatore M (2015) Evaluation of quantitative PET/MR enterography biomarkers for discrimination of inflammatory strictures from fibrotic strictures in Crohn disease. Radiology. https://doi.org/10.1148/radiol.2015150566

  33. 33.

    Pellino G, Nicolai E, Catalano OA, Campione S, D'Armiento FP, Salvatore M, Cuocolo A, Selvaggi F (2016) PET/MR versus PET/CT imaging: impact on the clinical management of small-bowel Crohn's disease. J Crohn's Colitis 10(3):277–285. https://doi.org/10.1093/ecco-jcc/jjv207

  34. 34.

    Kim YS, Jung SA, Lee KM, Park SJ, Kim TO, Choi CH, Kim HG, Moon W, Moon CM, Song HK, Na SY, Yang SK, (KASID) KAftSoID (2017) Impact of inflammatory bowel disease on daily life: an online survey by the Korean Association for the Study of Intestinal Diseases. Intest Res 15(3):338–344. https://doi.org/10.5217/ir.2017.15.3.338

  35. 35.

    Byrne CM, Pager CK, Rex J, Roberts R, Solomon MJ (2002) Assessment of quality of life in the treatment of patients with neuropathic fecal incontinence. Dis Colon Rectum 45(11):1431–1436. https://doi.org/10.1007/s10350-004-6444-1

  36. 36.

    Siegel CA, Whitman CB, Spiegel BMR, Feagan B, Sands B, Loftus EV, Panaccione R, D'Haens G, Bernstein CN, Gearry R, Ng SC, Mantzaris GJ, Sartor B, Silverberg MS, Riddell R, Koutroubakis IE, O'Morain C, Lakatos PL, McGovern DPB, Halfvarson J, Reinisch W, Rogler G, Kruis W, Tysk C, Schreiber S, Danese S, Sandborn W, Griffiths A, Moum B, Gasche C, Pallone F, Travis S, Panes J, Colombel JF, Hanauer S, Peyrin-Biroulet L (2018) Development of an index to define overall disease severity in IBD. Gut 67(2):244–254. https://doi.org/10.1136/gutjnl-2016-312648

  37. 37.

    Guyatt G, Mitchell A, Irvine EJ, Singer J, Williams N, Goodacre R, Tompkins C (1989) A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology 96(3):804–810

  38. 38.

    Satsangi J, Silverberg MS, Vermeire S, Colombel JF (2006) The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 55(6):749–753. https://doi.org/10.1136/gut.2005.082909

  39. 39.

    Khanna R, Nelson SA, Feagan BG, D'Haens G, Sandborn WJ, Zou GY, MacDonald JK, Parker CE, Jairath V, Levesque BG (2016) Endoscopic scoring indices for evaluation of disease activity in Crohn's disease. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD010642.pub2

  40. 40.

    Daperno M, D'Haens G, Van Assche G, Baert F, Bulois P, Maunoury V, Sostegni R, Rocca R, Pera A, Gevers A, Mary JY, Colombel JF, Rutgeerts P (2004) Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD. Gastrointest Endosc 60(4):505–512. https://doi.org/10.1016/s0016-5107(04)01878-4

  41. 41.

    Iacucci M, Daperno M, Lazarev M, Arsenascu R, Tontini GE, Akinola O, Gui XS, Villanacci V, Goetz M, Lowerison M, Lethebe BC, Vecchi M, Neumann H, Ghosh S, Bisschops R, Kiesslich R (2017) Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis. Gastrointest Endosc 86(6):1118–1127.e1115. https://doi.org/10.1016/j.gie.2017.03.012

  42. 42.

    Mohammed Vashist N, Samaan M, Mosli MH, Parker CE, MacDonald JK, Nelson SA, Zou GY, Feagan BG, Khanna R, Jairath V (2018) Endoscopic scoring indices for evaluation of disease activity in ulcerative colitis. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD011450.pub2

  43. 43.

    Morar PS, Sevdalis N, Warusavitarne J, Hart A, Green J, Edwards C, Faiz O (2018) Establishing the aims, format and function for multidisciplinary team-driven care within an inflammatory bowel disease service: a multicentre qualitative specialist-based consensus study. Frontline Gastroenterol 9(1):29–36. https://doi.org/10.1136/flgastro-2017-100835

  44. 44.

    Molander P, Jussila A, Toivonen T, Mäkkeli P, Alho A, Kolho KL (2018) The impacts of an inflammatory bowel disease nurse specialist on the quality of care and costs in Finland. Scand J Gastroenterol 53(12):1463–1468. https://doi.org/10.1080/00365521.2018.1541477

  45. 45.

    Casellas F, Herrera-de Guise C, Robles V, Navarro E, Borruel N (2017) Patient preferences for inflammatory bowel disease treatment objectives. Dig Liver Dis 49(2):152–156. https://doi.org/10.1016/j.dld.2016.09.009

  46. 46.

    Morar P, Read J, Arora S, Hart A, Warusavitarne J, Green J, Sevdalis N, Edwards C, Faiz O (2015) Defining the optimal design of the inflammatory bowel disease multidisciplinary team: results from a multicentre qualitative expert-based study. Frontline Gastroenterol 6(4):290–297. https://doi.org/10.1136/flgastro-2014-100549

  47. 47.

    Ferrante M, D'Hoore A, Vermeire S, Declerck S, Noman M, Van Assche G, Hoffman I, Rutgeerts P, Penninckx F (2009) Corticosteroids but not infliximab increase short-term postoperative infectious complications in patients with ulcerative colitis. Inflamm Bowel Dis 15(7):1062–1070. https://doi.org/10.1002/ibd.20863

  48. 48.

    Aberra FN, Lewis JD, Hass D, Rombeau JL, Osborne B, Lichtenstein GR (2003) Corticosteroids and immunomodulators: postoperative infectious complication risk in inflammatory bowel disease patients. Gastroenterology 125(2):320–327. https://doi.org/10.1016/s0016-5085(03)00883-7

  49. 49.

    Mahadevan U, Loftus EV, Tremaine WJ, Pemberton JH, Harmsen WS, Schleck CD, Zinsmeister AR, Sandborn WJ (2002) Azathioprine or 6-mercaptopurine before colectomy for ulcerative colitis is not associated with increased postoperative complications. Inflamm Bowel Dis 8(5):311–316. https://doi.org/10.1097/00054725-200209000-00001

  50. 50.

    El Hussuna A, Myrelid P, Holubar S, Kotze P, Mackenzie G, Pellino G, Winter D, Davies J, Negoi I, Grewal P, Gallo G, Sahnan K, Rubio-Perez I, Clerc D, Demartines N, Glasbey J, Regueiro M, Sherif A, Neary P, Pata F, Silverberg M, Clermont S, Chadi S, Emile S, Buchs N, Millan M, Minaya-Bravo A, Elfeki H, De Simone V, Shalaby M, Gutierrez C, Ozen C, Yalçınkaya A, Rivadeneira D, Sturiale A, Yassin N, Spinelli A, Warusavitarne J, Ioannidis A, Wexner S, Mayol J (2019) Biological treatment and the potential risk of adverse postoperative outcome in patients with inflammatory bowel disease: an open source expert panel review of the current literature and future perspectives. Crohn's Colitis. https://doi.org/10.1093/crocol/otz021

  51. 51.

    Yang Z, Wu Q, Wu K, Fan D (2010) Meta-analysis: pre-operative infliximab treatment and short-term post-operative complications in patients with ulcerative colitis. Aliment Pharmacol Ther 31(4):486–492. https://doi.org/10.1111/j.1365-2036.2009.04204.x

  52. 52.

    Rizzo G, Armuzzi A, Pugliese D, Verbo A, Papa A, Mattana C, Rapaccini GL, Guidi L, Coco C (2011) Anti-TNF-alpha therapies do not increase early postoperative complications in patients with inflammatory bowel disease: an Italian single-center experience. Int J Colorectal Dis 26(11):1435–1444. https://doi.org/10.1007/s00384-011-1236-2

  53. 53.

    Nørgård BM, Nielsen J, Qvist N, Gradel KO, de Muckadell OB, Kjeldsen J (2013) Pre-operative use of anti-TNF-α agents and the risk of post-operative complications in patients with Crohn's disease—a nationwide cohort study. Aliment Pharmacol Ther 37(2):214–224. https://doi.org/10.1111/apt.12159

  54. 54.

    Zangenberg MS, Horesh N, Kopylov U, El-Hussuna A (2017) Preoperative optimization of patients with inflammatory bowel disease undergoing gastrointestinal surgery: a systematic review. Int J Colorectal Dis 32(12):1663–1676. https://doi.org/10.1007/s00384-017-2915-4

  55. 55.

    Eshuis EJ, Al Saady RL, Stokkers PC, Ponsioen CY, Tanis PJ, Bemelman WA (2013) Previous infliximab therapy and postoperative complications after proctocolectomy with ileum pouch anal anastomosis. J Crohn's Colitis 7(2):142–149. https://doi.org/10.1016/j.crohns.2012.03.013

  56. 56.

    Selvaggi F, Pellino G, Canonico S, Sciaudone G (2015) Effect of preoperative biologic drugs on complications and function after restorative proctocolectomy with primary ileal pouch formation: systematic review and meta-analysis. Inflamm Bowel Dis 21(1):79–92. https://doi.org/10.1097/MIB.0000000000000232

  57. 57.

    Stoner PL, Kamel A, Ayoub F, Tan S, Iqbal A, Glover SC, Zimmermann EM (2018) Perioperative care of patients with inflammatory bowel disease: focus on nutritional support. Gastroenterol Res Pract 2018:7890161. https://doi.org/10.1155/2018/7890161

  58. 58.

    Li G, Ren J, Wang G, Hu D, Gu G, Liu S, Ren H, Wu X, Li J (2014) Preoperative exclusive enteral nutrition reduces the postoperative septic complications of fistulizing Crohn's disease. Eur J Clin Nutr 68(4):441–446. https://doi.org/10.1038/ejcn.2014.16

  59. 59.

    Forbes A, Escher J, Hébuterne X, Kłęk S, Krznaric Z, Schneider S, Shamir R, Stardelova K, Wierdsma N, Wiskin AE, Bischoff SC (2017) ESPEN guideline: clinical nutrition in inflammatory bowel disease. Clin Nutr 36(2):321–347. https://doi.org/10.1016/j.clnu.2016.12.027

  60. 60.

    Grass F, Pache B, Martin D, Hahnloser D, Demartines N, Hübner M (2017) Preoperative nutritional conditioning of Crohn's patients-systematic review of current evidence and practice. Nutrients. https://doi.org/10.3390/nu9060562

  61. 61.

    Kappelman MD, Horvath-Puho E, Sandler RS, Rubin DT, Ullman TA, Pedersen L, Baron JA, Sørensen HT (2011) Thromboembolic risk among Danish children and adults with inflammatory bowel diseases: a population-based nationwide study. Gut 60(7):937–943. https://doi.org/10.1136/gut.2010.228585

  62. 62.

    Novacek G, Weltermann A, Sobala A, Tilg H, Petritsch W, Reinisch W, Mayer A, Haas T, Kaser A, Feichtenschlager T, Fuchssteiner H, Knoflach P, Vogelsang H, Miehsler W, Platzer R, Tillinger W, Jaritz B, Schmid A, Blaha B, Dejaco C, Eichinger S (2010) Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism. Gastroenterology 139(3):779–787. https://doi.org/10.1053/j.gastro.2010.05.026

  63. 63.

    Grainge MJ, West J, Card TR (2010) Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study. Lancet 375(9715):657–663. https://doi.org/10.1016/S0140-6736(09)61963-2

  64. 64.

    Merrill A, Millham F (2012) Increased risk of postoperative deep vein thrombosis and pulmonary embolism in patients with inflammatory bowel disease: a study of National Surgical Quality Improvement Program patients. Arch Surg 147(2):120–124. https://doi.org/10.1001/archsurg.2011.297

  65. 65.

    Dignass A, Van Assche G, Lindsay JO, Lémann M, Söderholm J, Colombel JF, Danese S, D'Hoore A, Gassull M, Gomollón F, Hommes DW, Michetti P, O'Morain C, Oresland T, Windsor A, Stange EF, Travis SP, (ECCO) ECsaCO (2010) The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: current management. J Crohn's Colitis 4(1):28–62. https://doi.org/10.1016/j.crohns.2009.12.002

  66. 66.

    Brady MT, Patts GJ, Rosen A, Kasotakis G, Siracuse JJ, Sachs T, Kuhnen A, Kunitake H (2017) Postoperative venous thromboembolism in patients undergoing abdominal surgery for IBD: a common but rarely addressed problem. Dis Colon Rectum 60(1):61–67. https://doi.org/10.1097/DCR.0000000000000721

  67. 67.

    Gross ME, Vogler SA, Mone MC, Sheng X, Sklow B (2014) The importance of extended postoperative venous thromboembolism prophylaxis in IBD: a National Surgical Quality Improvement Program analysis. Dis Colon Rectum 57(4):482–489. https://doi.org/10.1097/DCR.0000000000000090

  68. 68.

    Research USDoHaHSFCfDEa, Research USDoHaHSFCfBEa, Health, USDoHaHSFCfDaR (2006) Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. Health Qual Life Outcomes 4:79. https://doi.org/10.1186/1477-7525-4-79

  69. 69.

    Bojic D, Bodger K, Travis S (2017) Patient reported outcome measures (PROMs) in inflammatory bowel disease: new data. J Crohn's Colitis 11:S576–S585. https://doi.org/10.1093/ecco-jcc/jjw187

  70. 70.

    Harbord M, Eliakim R, Bettenworth D, Karmiris K, Katsanos K, Kopylov U, Kucharzik T, Molnár T, Raine T, Sebastian S, de Sousa HT, Dignass A, Carbonnel F, Organisation ECsaC, [ECCO] (2017) Third European evidence-based consensus on diagnosis and management of ulcerative colitis: part 2: current management. J Crohn's Colitis 11(7):769–784. https://doi.org/10.1093/ecco-jcc/jjx009

  71. 71.

    Burisch J, Jess T, Martinato M, Lakatos PL, EpiCom E (2013) The burden of inflammatory bowel disease in Europe. J Crohn's Colitis 7(4):322–337. https://doi.org/10.1016/j.crohns.2013.01.010

  72. 72.

    Larsson S, Lawyer P, Garellick G, Lindahl B, Lundström M (2012) Use of 13 disease registries in 5 countries demonstrates the potential to use outcome data to improve health care's value. Health Aff (Millwood) 31(1):220–227. https://doi.org/10.1377/hlthaff.2011.0762

  73. 73.

    Crandall WV, Margolis PA, Kappelman MD, King EC, Pratt JM, Boyle BM, Duffy LF, Grunow JE, Kim SC, Leibowitz I, Schoen BT, Colletti RB, Collaborative I (2012) Improved outcomes in a quality improvement collaborative for pediatric inflammatory bowel disease. Pediatrics 129(4):e1030–1041. https://doi.org/10.1542/peds.2011-1700

  74. 74.

    Peyrin-Biroulet L, Sandborn W, Sands BE, Reinisch W, Bemelman W, Bryant RV, D'Haens G, Dotan I, Dubinsky M, Feagan B, Fiorino G, Gearry R, Krishnareddy S, Lakatos PL, Loftus EV, Marteau P, Munkholm P, Murdoch TB, Ordás I, Panaccione R, Riddell RH, Ruel J, Rubin DT, Samaan M, Siegel CA, Silverberg MS, Stoker J, Schreiber S, Travis S, Van Assche G, Danese S, Panes J, Bouguen G, O'Donnell S, Pariente B, Winer S, Hanauer S, Colombel JF (2015) Selecting therapeutic targets in inflammatory bowel disease (STRIDE): determining therapeutic goals for treat-to-target. Am J Gastroenterol 110(9):1324–1338. https://doi.org/10.1038/ajg.2015.233

  75. 75.

    Pouillon L, Peyrin-Biroulet L (2018) It is time to revise the STRIDE guidelines determining therapeutic goals for treat-to-target in inflammatory bowel disease. J Crohn's Colitis 12(4):509. https://doi.org/10.1093/ecco-jcc/jjx174

  76. 76.

    Ma C, Hussein IM, Al-Abbar YJ, Panaccione R, Fedorak RN, Parker CE, Nguyen TM, Khanna R, Siegel CA, Peyrin-Biroulet L, Pai RK, Vande Casteele N, D'Haens GR, Sandborn WJ, Feagan BG, Jairath V (2018) Heterogeneity in definitions of efficacy and safety endpoints for clinical trials of crohn's disease: a systematic review. Clin Gastroenterol Hepatol 16(9):1407–1419.e1422. https://doi.org/10.1016/j.cgh.2018.02.051

  77. 77.

    Ma C, Panaccione R, Fedorak RN, Parker CE, Nguyen TM, Khanna R, Siegel CA, Peyrin-Biroulet L, D'Haens G, Sandborn WJ, Feagan BG, Jairath V (2018) Heterogeneity in definitions of endpoints for clinical trials of ulcerative colitis: a systematic review for development of a core outcome set. Clin Gastroenterol Hepatol 16(5):637–647.e613. https://doi.org/10.1016/j.cgh.2017.08.025

  78. 78.

    D'Haens G, Feagan B, Colombel JF, Sandborn WJ, Reinisch W, Rutgeerts P, Carbonnel F, Mary JY, Danese S, Fedorak RN, Hanauer S, Lémann M, (ECCO) IOfIBDIatCTCCotECsaCO (2012) Challenges to the design, execution, and analysis of randomized controlled trials for inflammatory bowel disease. Gastroenterology 143(6):1461–1469. https://doi.org/10.1053/j.gastro.2012.09.031

  79. 79.

    Williamson PR, Altman DG, Blazeby JM, Clarke M, Devane D, Gargon E, Tugwell P (2012) Developing core outcome sets for clinical trials: issues to consider. Trials 13:132. https://doi.org/10.1186/1745-6215-13-132

  80. 80.

    Porter ME, Larsson S, Lee TH (2016) Standardizing patient outcomes measurement. N Engl J Med 374(6):504–506. https://doi.org/10.1056/NEJMp1511701

  81. 81.

    Kim AH, Roberts C, Feagan BG, Banerjee R, Bemelman W, Bodger K, Derieppe M, Dignass A, Driscoll R, Fitzpatrick R, Gaarentstroom-Lunt J, Higgins PD, Kotze PG, Meissner J, O'Connor M, Ran ZH, Siegel CA, Terry H, van Deen WK, van der Woude CJ, Weaver A, Yang SK, Sands BE, Vermeire S, Travis SP (2018) Developing a standard set of patient-centred outcomes for inflammatory bowel disease-an international, cross-disciplinary consensus. J Crohn's Colitis 12(4):408–418. https://doi.org/10.1093/ecco-jcc/jjx161

  82. 82.

    Clara I, Lix LM, Walker JR, Graff LA, Miller N, Rogala L, Rawsthorne P, Bernstein CN (2009) The Manitoba IBD Index: evidence for a new and simple indicator of IBD activity. Am J Gastroenterol 104(7):1754–1763. https://doi.org/10.1038/ajg.2009.197

  83. 83.

    Johnston WF, Stafford C, Francone TD, Read TE, Marcello PW, Roberts PL, Ricciardi R (2017) What is the risk of anastomotic leak after repeat intestinal resection in patients with Crohn's disease? Dis Colon Rectum 60(12):1299–1306. https://doi.org/10.1097/DCR.0000000000000946

  84. 84.

    Bouquot M, Maggiori L, Hain E, Prost A, la Denise J, Bouhnik Y, Panis Y (2019) What is the outcome for patients undergoing more than two ileocolonic resections for recurrent Crohn's disease? A comparative study of 569 consecutive procedures. Colorectal Dis 21(5):563–569. https://doi.org/10.1111/codi.14562

  85. 85.

    Egan L, D'Inca R, Jess T, Pellino G, Carbonnel F, Bokemeyer B, Harbord M, Nunes P, Van der Woude J, Selvaggi F, Triantafillidis J (2014) Non-colorectal intestinal tract carcinomas in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (II). J Crohn's Colitis 8(1):19–30. https://doi.org/10.1016/j.crohns.2013.04.009

  86. 86.

    Laukoetter MG, Mennigen R, Hannig CM, Osada N, Rijcken E, Vowinkel T, Krieglstein CF, Senninger N, Anthoni C, Bruewer M (2011) Intestinal cancer risk in Crohn's disease: a meta-analysis. J Gastrointest Surg 15(4):576–583. https://doi.org/10.1007/s11605-010-1402-9

  87. 87.

    Piton G, Cosnes J, Monnet E, Beaugerie L, Seksik P, Savoye G, Cadiot G, Flourie B, Capelle P, Marteau P, Lemann M, Colombel JF, Khouri E, Bonaz B, Carbonnel F (2008) Risk factors associated with small bowel adenocarcinoma in Crohn's disease: a case-control study. Am J Gastroenterol 103(7):1730–1736. https://doi.org/10.1111/j.1572-0241.2008.01847.x

  88. 88.

    Vanoli A, Di Sabatino A, Martino M, Klersy C, Grillo F, Mescoli C, Nesi G, Volta U, Fornino D, Luinetti O, Fociani P, Villanacci V, D'Armiento FP, Cannizzaro R, Latella G, Ciacci C, Biancone L, Paulli M, Sessa F, Rugge M, Fiocca R, Corazza GR, Solcia E (2017) Small bowel carcinomas in celiac or Crohn's disease: distinctive histophenotypic, molecular and histogenetic patterns. Mod Pathol 30(10):1453–1466. https://doi.org/10.1038/modpathol.2017.40

  89. 89.

    Scharl M, Frei P, Frei SM, Biedermann L, Weber A, Rogler G (2014) Epithelial-to-mesenchymal transition in a fistula-associated anal adenocarcinoma in a patient with long-standing Crohn's disease. Eur J Gastroenterol Hepatol 26(1):114–118. https://doi.org/10.1097/MEG.0b013e32836371a2

  90. 90.

    Baars JE, Kuipers EJ, Dijkstra G, Hommes DW, de Jong DJ, Stokkers PC, Oldenburg B, Pierik M, Wahab PJ, van Bodegraven AA, van der Woude CJ, IfCa C (2011) Malignant transformation of perianal and enterocutaneous fistulas is rare: results of 17 years of follow-up from The Netherlands. Scand J Gastroenterol 46(3):319–325. https://doi.org/10.3109/00365521.2010.536251

  91. 91.

    Lightdale CJ, Sternberg SS, Posner G, Sherlock P (1975) Carcinoma complicating Crohn's disease: report of seven cases and review of the literature. Am J Med 59(2):262–268. https://doi.org/10.1016/0002-9343(75)90361-7

  92. 92.

    Zefelippo A, Costa S, Caprioli F, Contessini-Avesani E (2015) Perianal Crohn's disease and fistula-associated carcinoma: challenges in diagnosis. Int J Colorectal Dis 30(11):1589–1591. https://doi.org/10.1007/s00384-015-2140-y

  93. 93.

    Wisniewski A, Fléjou JF, Siproudhis L, Abramowitz L, Svrcek M, Beaugerie L (2017) Anal neoplasia in inflammatory bowel disease: classification proposal, epidemiology, carcinogenesis, and risk management perspectives. J Crohn's Colitis 11(8):1011–1018. https://doi.org/10.1093/ecco-jcc/jjx035

  94. 94.

    Traube J, Simpson S, Riddell RH, Levin B, Kirsner JB (1980) Crohn's disease and adenocarcinoma of the bowel. Dig Dis Sci 25(12):939–944. https://doi.org/10.1007/bf01308045

  95. 95.

    Slesser AA, Bhangu A, Bower M, Goldin R, Tekkis PP (2013) A systematic review of anal squamous cell carcinoma in inflammatory bowel disease. Surg Oncol 22(4):230–237. https://doi.org/10.1016/j.suronc.2013.08.002

  96. 96.

    Smith R, Hicks D, Tomljanovich PI, Lele SB, Rajput A, Dunn KB (2008) Adenocarcinoma arising from chronic perianal Crohn's disease: case report and review of the literature. Am Surg 74(1):59–61

  97. 97.

    Ball CS, Wujanto R, Haboubi NY, Schofield PF (1988) Carcinoma in anal Crohn's disease: discussion paper. J R Soc Med 81(4):217–219

  98. 98.

    Pellino G (2014) Immunosuppression may exert a hypoxia-mediated carcinogenetic effect in long-standing fistulizing Crohn's disease. Eur J Gastroenterol Hepatol 26:575–576. https://doi.org/10.1097/meg.0000000000000077

  99. 99.

    Freeman HJ, Perry T, Webber DL, Chang SD, Loh MY (2010) Mucinous carcinoma in Crohn's disease originating in a fistulous tract. World J Gastrointest Oncol 2(7):307–310. https://doi.org/10.4251/wjgo.v2.i7.307

  100. 100.

    Ky A, Sohn N, Weinstein MA, Korelitz BI (1998) Carcinoma arising in anorectal fistulas of Crohn's disease. Dis Colon Rectum 41(8):992–996. https://doi.org/10.1007/bf02237388

  101. 101.

    Devon KM, Brown CJ, Burnstein M, McLeod RS (2009) Cancer of the anus complicating perianal Crohn's disease. Dis Colon Rectum 52(2):211–216. https://doi.org/10.1007/DCR.0b013e318197d0ad

  102. 102.

    Devroe H, Coene L, Mortelmans LJ, Jutten G (2005) Colloid carcinoma arising in an anorectal fistula in Crohn's disease: a case report. Acta Chir Belg 105(1):110–111

  103. 103.

    Iesalnieks I, Gaertner WB, Glass H, Strauch U, Hipp M, Agha A, Schlitt HJ (2010) Fistula-associated anal adenocarcinoma in Crohn's disease. Inflamm Bowel Dis 16(10):1643–1648. https://doi.org/10.1002/ibd.21228

  104. 104.

    Benjelloun EB, Abkari M, Ousadden A, Ait-Taleb K (2013) Squamous cell carcinoma associated anal fistulas in Crohn's disease unique case report with literature review. J Crohn's Colitis 7(6):e232–235. https://doi.org/10.1016/j.crohns.2012.09.015

  105. 105.

    Gaertner WB, Hagerman GF, Finne CO, Alavi K, Jessurun J, Rothenberger DA, Madoff RD (2008) Fistula-associated anal adenocarcinoma: good results with aggressive therapy. Dis Colon Rectum 51(7):1061–1067. https://doi.org/10.1007/s10350-008-9294-4

  106. 106.

    Ogawa H, Haneda S, Shibata C, Miura K, Nagao M, Ohnuma S, Kohyama A, Unno M (2013) Adenocarcinoma associated with perianal fistulas in Crohn's disease. Anticancer Res 33(2):685–689

  107. 107.

    Stidham RW, Higgins PDR (2018) Colorectal cancer in inflammatory bowel disease. Clin Colon Rectal Surg 31(3):168–178. https://doi.org/10.1055/s-0037-1602237

  108. 108.

    Jess T, Gamborg M, Matzen P, Munkholm P, Sørensen TI (2005) Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies. Am J Gastroenterol 100(12):2724–2729. https://doi.org/10.1111/j.1572-0241.2005.00287.x

  109. 109.

    Jess T, Rungoe C, Peyrin-Biroulet L (2012) Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. Clin Gastroenterol Hepatol 10(6):639–645. https://doi.org/10.1016/j.cgh.2012.01.010

  110. 110.

    Collins PD, Mpofu C, Watson AJ, Rhodes JM (2006) Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD000279.pub3

  111. 111.

    Provenzale D, Wong JB, Onken JE, Lipscomb J (1998) Performing a cost-effectiveness analysis: surveillance of patients with ulcerative colitis. Am J Gastroenterol 93(6):872–880. https://doi.org/10.1111/j.1572-0241.1998.00314.x

  112. 112.

    Selvaggi F, Pellino G (2014) Cuff and pouch cancer in patients with inflammatory bowel disease: what surveillance strategy should be recommended? Reply. Inflamm Bowel Dis 20(8):E20–E21. https://doi.org/10.1097/MIB.0000000000000097

  113. 113.

    Pellino G, Kontovounisios C, Tait D, Nicholls J, Tekkis PP (2017) Squamous cell carcinoma of the anal transitional zone after ileal pouch surgery for ulcerative colitis: systematic review and treatment perspectives. Case Rep Oncol 10(1):112–122. https://doi.org/10.1159/000455898

  114. 114.

    Pulusu SSR, Lawrance IC (2017) Dysplasia and colorectal cancer surveillance in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol 11(8):711–722. https://doi.org/10.1080/17474124.2017.1327347

  115. 115.

    Basseri RJ, Basseri B, Papadakis KA (2011) Dysplasia and cancer in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol 5(1):59–66. https://doi.org/10.1586/egh.10.77

  116. 116.

    Beaugerie L, Svrcek M, Seksik P, Bouvier AM, Simon T, Allez M, Brixi H, Gornet JM, Altwegg R, Beau P, Duclos B, Bourreille A, Faivre J, Peyrin-Biroulet L, Fléjou JF, Carrat F, Group CS (2013) Risk of colorectal high-grade dysplasia and cancer in a prospective observational cohort of patients with inflammatory bowel disease. Gastroenterology 145(1):166–175. https://doi.org/10.1053/j.gastro.2013.03.044

  117. 117.

    Matkowskyj KA, Chen ZE, Rao MS, Yang GY (2013) Dysplastic lesions in inflammatory bowel disease: molecular pathogenesis to morphology. Arch Pathol Lab Med 137(3):338–350. https://doi.org/10.5858/arpa.2012-0086-RA

  118. 118.

    Beaugerie L, Itzkowitz SH (2015) Cancers complicating inflammatory bowel disease. N Engl J Med 372(15):1441–1452. https://doi.org/10.1056/NEJMra1403718

  119. 119.

    Keller DS, Windsor A, Cohen R, Chand M (2019) Colorectal cancer in inflammatory bowel disease: review of the evidence. Tech Coloproctol 23(1):3–13. https://doi.org/10.1007/s10151-019-1926-2

  120. 120.

    Bettington M, Walker N, Clouston A, Brown I, Leggett B, Whitehall V (2013) The serrated pathway to colorectal carcinoma: current concepts and challenges. Histopathology 62(3):367–386. https://doi.org/10.1111/his.12055

  121. 121.

    Bossard C, Denis MG, Bézieau S, Bach-Ngohou K, Bourreille A, Laboisse CL, Mosnier JF (2007) Involvement of the serrated neoplasia pathway in inflammatory bowel disease-related colorectal oncogenesis. Oncol Rep 18(5):1093–1097

  122. 122.

    Kaltenbach T, Sandborn WJ (2017) Endoscopy in inflammatory bowel disease: advances in dysplasia detection and management. Gastrointest Endosc 86(6):962–971. https://doi.org/10.1016/j.gie.2017.09.030

  123. 123.

    Laine L, Kaltenbach T, Barkun A, McQuaid KR, Subramanian V, Soetikno R, Panel SGD (2015) SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastrointest Endosc 81(3):489–501. https://doi.org/10.1016/j.gie.2014.12.009

  124. 124.

    Schlemper RJ, Riddell RH, Kato Y, Borchard F, Cooper HS, Dawsey SM, Dixon MF, Fenoglio-Preiser CM, Fléjou JF, Geboes K, Hattori T, Hirota T, Itabashi M, Iwafuchi M, Iwashita A, Kim YI, Kirchner T, Klimpfinger M, Koike M, Lauwers GY, Lewin KJ, Oberhuber G, Offner F, Price AB, Rubio CA, Shimizu M, Shimoda T, Sipponen P, Solcia E, Stolte M, Watanabe H, Yamabe H (2000) The Vienna classification of gastrointestinal epithelial neoplasia. Gut 47(2):251–255. https://doi.org/10.1136/gut.47.2.251

  125. 125.

    Odze RD (2006) Pathology of dysplasia and cancer in inflammatory bowel disease. Gastroenterol Clin North Am 35(3):533–552. https://doi.org/10.1016/j.gtc.2006.07.007

  126. 126.

    Svrcek M, Borralho Nunes P, Villanacci V, Beaugerie L, Rogler G, De Hertogh G, Tripathi M, Feakins R, Group H-E (2018) Clinicopathological and molecular specificities of inflammatory bowel disease-related colorectal neoplastic lesions: the role of inflammation. J Crohn's Colitis 12(12):1486–1498. https://doi.org/10.1093/ecco-jcc/jjy132

  127. 127.

    Pironi L, Arends J, Baxter J, Bozzetti F, Peláez RB, Cuerda C, Forbes A, Gabe S, Gillanders L, Holst M, Jeppesen PB, Joly F, Kelly D, Klek S, Irtun Ø, Olde Damink SW, Panisic M, Rasmussen HH, Staun M, Szczepanek K, Van Gossum A, Wanten G, Schneider SM, Shaffer J, Failure HANCI, ESPEN AIFSIGo (2015) ESPEN endorsed recommendations: definition and classification of intestinal failure in adults. Clin Nutr 34(2):171–180. https://doi.org/10.1016/j.clnu.2014.08.017

  128. 128.

    Pironi L, Corcos O, Forbes A, Holst M, Joly F, Jonkers C, Klek S, Lal S, Blaser AR, Rollins KE, Sasdelli AS, Shaffer J, Van Gossum A, Wanten G, Zanfi C, Lobo DN, Groups EAaCIFSI (2018) Intestinal failure in adults: recommendations from the ESPEN expert groups. Clin Nutr 37:1798–1809. https://doi.org/10.1016/j.clnu.2018.07.036

  129. 129.

    Uchino M, Ikeuchi H, Bando T, Matsuoka H, Takahashi Y, Takesue Y, Matsumoto T, Tomita N (2012) Risk factors for short bowel syndrome in patients with Crohn's disease. Surg Today 42(5):447–452. https://doi.org/10.1007/s00595-011-0098-0

  130. 130.

    Gearry RB, Kamm MA, Hart AL, Bassett P, Gabe SM, Nightingale JM (2013) Predictors for developing intestinal failure in patients with Crohn's disease. J Gastroenterol Hepatol 28(5):801–807. https://doi.org/10.1111/jgh.12115

  131. 131.

    Limketkai BN, Parian AM, Shah ND, Colombel JF (2016) Short bowel syndrome and intestinal failure in Crohn's disease. Inflamm Bowel Dis 22(5):1209–1218. https://doi.org/10.1097/MIB.0000000000000698

  132. 132.

    Yamamoto T, Fazio VW, Tekkis PP (2007) Safety and efficacy of strictureplasty for Crohn's disease: a systematic review and meta-analysis. Dis Colon Rectum 50(11):1968–1986. https://doi.org/10.1007/s10350-007-0279-5

  133. 133.

    Morar PS, Hodgkinson JD, Thalayasingam S, Koysombat K, Purcell M, Hart AL, Warusavitarne J, Faiz O (2015) Determining predictors for intra-abdominal septic complications following ileocolonic resection for Crohn's disease-considerations in pre-operative and peri-operative optimisation techniques to improve outcome. J Crohn's Colitis 9(6):483–491. https://doi.org/10.1093/ecco-jcc/jjv051

  134. 134.

    Huang W, Tang Y, Nong L, Sun Y (2015) Risk factors for postoperative intra-abdominal septic complications after surgery in Crohn's disease: a meta-analysis of observational studies. J Crohn's Colitis 9(3):293–301. https://doi.org/10.1093/ecco-jcc/jju028

  135. 135.

    Sigall-Boneh R, Levine A, Lomer M, Wierdsma N, Allan P, Fiorino G, Gatti S, Jonkers D, Kierkus J, Katsanos KH, Melgar S, Yuksel ES, Whelan K, Wine E, Gerasimidis K (2017) Research gaps in diet and nutrition in inflammatory bowel disease: a topical review by D-ECCO Working Group [Dietitians of ECCO]. J Crohn's Colitis 11(12):1407–1419. https://doi.org/10.1093/ecco-jcc/jjx109

  136. 136.

    Sandhu A, Mosli M, Yan B, Wu T, Gregor J, Chande N, Ponich T, Beaton M, Rahman A (2016) Self-screening for malnutrition risk in outpatient inflammatory bowel disease patients using the malnutrition universal screening tool (MUST). JPEN J Parenter Enteral Nutr 40(4):507–510. https://doi.org/10.1177/0148607114566656

  137. 137.

    Luo M, Fernández-Estívariz C, Manatunga AK, Bazargan N, Gu LH, Jones DP, Klapproth JM, Sitaraman SV, Leader LM, Galloway JR, Ziegler TR (2007) Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome? JPEN J Parenter Enteral Nutr 31(1):1–7. https://doi.org/10.1177/014860710703100101

  138. 138.

    Stephens AN, Pereira-Fantini PM, Wilson G, Taylor RG, Rainczuk A, Meehan KL, Sourial M, Fuller PJ, Stanton PG, Robertson DM, Bines JE (2010) Proteomic analysis of the intestinal adaptation response reveals altered expression of fatty acid binding proteins following massive small bowel resection. J Proteome Res 9(3):1437–1449. https://doi.org/10.1021/pr900976f

  139. 139.

    Howard L, Ament M, Fleming CR, Shike M, Steiger E (1995) Current use and clinical outcome of home parenteral and enteral nutrition therapies in the United States. Gastroenterology 109(2):355–365. https://doi.org/10.1016/0016-5085(95)90321-6

  140. 140.

    Howard L, Heaphey L, Fleming CR, Lininger L, Steiger E (1991) Four years of North American registry home parenteral nutrition outcome data and their implications for patient management. JPEN J Parenter Enteral Nutr 15(4):384–393. https://doi.org/10.1177/0148607191015004384

  141. 141.

    Kalaiselvan R, Theis VS, Dibb M, Teubner A, Anderson ID, Shaffer JL, Carlson GL, Lal S (2014) Radiation enteritis leading to intestinal failure: 1994 patient-years of experience in a national referral centre. Eur J Clin Nutr 68(2):166–170. https://doi.org/10.1038/ejcn.2013.251

  142. 142.

    Gyorki DE, Brooks CE, Gett R, Woods RJ, Johnston M, Keck JO, Mackay JR, Heriot AG (2010) Enterocutaneous fistula: a single-centre experience. ANZ J Surg 80(3):178–181. https://doi.org/10.1111/j.1445-2197.2009.05086.x

  143. 143.

    Staun M, Pironi L, Bozzetti F, Baxter J, Forbes A, Joly F, Jeppesen P, Moreno J, Hébuterne X, Pertkiewicz M, Mühlebach S, Shenkin A, Van Gossum A, ESPEN (2009) ESPEN guidelines on parenteral nutrition: home parenteral nutrition (HPN) in adult patients. Clin Nutr 28(4):467–479. https://doi.org/10.1016/j.clnu.2009.04.001

  144. 144.

    Vaizey CJ, Maeda Y, Barbosa E, Bozzetti F, Calvo J, Irtun Ø, Jeppesen PB, Klek S, Panisic-Sekeljic M, Papaconstantinou I, Pascher A, Panis Y, Wallace WD, Carlson G, Boermeester M, Group: EIF (2016) European Society of Coloproctology consensus on the surgical management of intestinal failure in adults. Colorectal Dis 18(6):535–548. https://doi.org/10.1111/codi.13321

  145. 145.

    Grainger JT, Maeda Y, Donnelly SC, Vaizey CJ (2018) Assessment and management of patients with intestinal failure: a multidisciplinary approach. Clin Exp Gastroenterol 11:233–241. https://doi.org/10.2147/CEG.S122868

  146. 146.

    Ba'ath ME, Mahmalat MW, Kapur P, Smith NP, Dalzell AM, Casson DH, Lamont GL, Baillie CT (2007) Surgical management of inflammatory bowel disease. Arch Dis Child 92(4):312–316. https://doi.org/10.1136/adc.2006.096875

  147. 147.

    Amil-Dias J, Kolacek S, Turner D, Pærregaard A, Rintala R, Afzal NA, Karolewska-Bochenek K, Bronsky J, Chong S, Fell J, Hojsak I, Hugot JP, Koletzko S, Kumar D, Lazowska-Przeorek I, Lillehei C, Lionetti P, Martin-de-Carpi J, Pakarinen M, Ruemmele FM, Shaoul R, Spray C, Staiano A, Sugarman I, Wilson DC, Winter H, Kolho KL, Group IWGoEIP (2017) Surgical management of crohn disease in children: guidelines from the paediatric IBD Porto Group of ESPGHAN. J Pediatr Gastroenterol Nutr 64(5):818–835. https://doi.org/10.1097/MPG.0000000000001562

  148. 148.

    Di Abriola GF, De Angelis P, Dall'oglio L, Di Lorenzo M (2003) Strictureplasty: an alternative approach in long segment bowel stenosis Crohn's disease. J Pediatr Surg 38(5):814–818. https://doi.org/10.1016/jpsu.2003.50173

  149. 149.

    Ruemmele FM, Veres G, Kolho KL, Griffiths A, Levine A, Escher JC, Amil Dias J, Barabino A, Braegger CP, Bronsky J, Buderus S, Martín-de-Carpi J, De Ridder L, Fagerberg UL, Hugot JP, Kierkus J, Kolacek S, Koletzko S, Lionetti P, Miele E, Navas López VM, Paerregaard A, Russell RK, Serban DE, Shaoul R, Van Rheenen P, Veereman G, Weiss B, Wilson D, Dignass A, Eliakim A, Winter H, Turner D, Organisation ECsaC, European Society of Pediatric Gastroenterology HpaN (2014) Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease. J Crohn's Colitis 8(10):1179–1207. https://doi.org/10.1016/j.crohns.2014.04.005

  150. 150.

    de Zoeten EF, Pasternak BA, Mattei P, Kramer RE, Kader HA (2013) Diagnosis and treatment of perianal Crohn disease: NASPGHAN clinical report and consensus statement. J Pediatr Gastroenterol Nutr 57(3):401–412. https://doi.org/10.1097/MPG.0b013e3182a025ee

  151. 151.

    Dharmaraj R, Nugent M, Simpson P, Arca M, Gurram B, Werlin S (2018) Outcomes after fecal diversion for colonic and perianal Crohn disease in children. J Pediatr Surg 53(3):472–476. https://doi.org/10.1016/j.jpedsurg.2017.08.011

  152. 152.

    Mattioli G, Pio L, Arrigo S, Pini Prato A, Montobbio G, Disma NM, Barabino A (2015) Cone-like resection, fistulectomy and mucosal rectal sleeve partial endorectal pull-through in paediatric Crohn's disease with perianal complex fistula. Dig Liver Dis 47(8):658–662. https://doi.org/10.1016/j.dld.2015.05.003

  153. 153.

    Simon T, Orangio G, Ambroze W, Schertzer M, Armstrong D (2003) Laparoscopic-assisted bowel resection in pediatric/adolescent inflammatory bowel disease: laparoscopic bowel resection in children. Dis Colon Rectum 46(10):1325–1331. https://doi.org/10.1007/s10350-004-6742-7

  154. 154.

    von Allmen D, Markowitz JE, York A, Mamula P, Shepanski M, Baldassano R (2003) Laparoscopic-assisted bowel resection offers advantages over open surgery for treatment of segmental Crohn's disease in children. J Pediatr Surg 38(6):963–965. https://doi.org/10.1016/s0022-3468(03)00134-9

  155. 155.

    Macaluso FS, Cavallaro F, Felice C, Mazza M, Armuzzi A, Gionchetti P, Vecchi M, Orlando A (2019) Risk factors and timing for colectomy in chronically active refractory ulcerative colitis: a systematic review. Dig Liver Dis 51(5):613–620. https://doi.org/10.1016/j.dld.2019.01.018

  156. 156.

    Tilney HS, Constantinides V, Ioannides AS, Tekkis PP, Darzi AW, Haddad MJ (2006) Pouch–anal anastomosis vs straight ileoanal anastomosis in pediatric patients: a meta-analysis. J Pediatr Surg 41(11):1799–1808. https://doi.org/10.1016/j.jpedsurg.2006.06.005

  157. 157.

    Weston-Petrides GK, Lovegrove RE, Tilney HS, Heriot AG, Nicholls RJ, Mortensen NJ, Fazio VW, Tekkis PP (2008) Comparison of outcomes after restorative proctocolectomy with or without defunctioning ileostomy. Arch Surg 143(4):406–412. https://doi.org/10.1001/archsurg.143.4.406

  158. 158.

    Pellino G, Selvaggi F (2014) Restorative proctocolectomy in pediatric patients. J Am Coll Surg 219(5):1106. https://doi.org/10.1016/j.jamcollsurg.2014.07.938

  159. 159.

    Ross H, Steele SR, Varma M, Dykes S, Cima R, Buie WD, Rafferty J, Surgeons SPTFotASoCaR (2014) Practice parameters for the surgical treatment of ulcerative colitis. Dis Colon Rectum 57(1):5–22. https://doi.org/10.1097/DCR.0000000000000030

  160. 160.

    Mattioli G, Pini-Prato A, Barabino A, Gandullia P, Avanzini S, Guida E, Rossi V, Pio L, Disma N, Mameli L, Mirta DR, Montobbio G, Jasonni V (2011) Laparoscopic approach for children with inflammatory bowel diseases. Pediatr Surg Int 27(8):839–846. https://doi.org/10.1007/s00383-011-2885-5

  161. 161.

    Muntean A, Stoica I, McMahon SV, Mortell A, Gillick J, Sweeney BT (2019) Colectomies in children with inflammatory bowel disease: a national referral centre experience. Pediatr Surg Int 35(6):691–698. https://doi.org/10.1007/s00383-019-04467-4

  162. 162.

    Hait E, Arnold JH, Fishman LN (2006) Educate, communicate, anticipate-practical recommendations for transitioning adolescents with IBD to adult health care. Inflamm Bowel Dis 12(1):70–73. https://doi.org/10.1097/01.mib.0000194182.85047.6a

  163. 163.

    Goodhand J, Hedin CR, Croft NM, Lindsay JO (2011) Adolescents with IBD: the importance of structured transition care. J Crohn's Colitis 5(6):509–519. https://doi.org/10.1016/j.crohns.2011.03.015

  164. 164.

    van Rheenen PF, Aloi M, Biron IA, Carlsen K, Cooney R, Cucchiara S, Cullen G, Escher JC, Kierkus J, Lindsay JO, Roma E, Russell RK, Sieczkowska-Golub J, Harbord M (2017) European Crohn's and colitis organisation topical review on transitional care in inflammatory bowel disease. J Crohn's Colitis 11(9):1032–1038. https://doi.org/10.1093/ecco-jcc/jjx010

  165. 165.

    Cole R, Ashok D, Razack A, Azaz A, Sebastian S (2015) Evaluation of outcomes in adolescent inflammatory bowel disease patients following transfer from pediatric to adult health care services: case for transition. J Adolesc Health 57(2):212–217. https://doi.org/10.1016/j.jadohealth.2015.04.012

  166. 166.

    Iannotti RJ, Schneider S, Nansel TR, Haynie DL, Plotnick LP, Clark LM, Sobel DO, Simons-Morton B (2006) Self-efficacy, outcome expectations, and diabetes self-management in adolescents with type 1 diabetes. J Dev Behav Pediatr 27(2):98–105

  167. 167.

    Izaguirre MR, Keefer L (2014) Development of a self-efficacy scale for adolescents and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 59(1):29–32. https://doi.org/10.1097/MPG.0000000000000357

  168. 168.

    Izaguirre MR, Taft T, Keefer L (2017) Validation of a self-efficacy scale for adolescents and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. https://doi.org/10.1097/mpg.0000000000001552

  169. 169.

    Higashiyama M, Sugita A, Koganei K, Wanatabe K, Yokoyama Y, Uchino M, Nagahori M, Naganuma M, Bamba S, Kato S, Takeuchi K, Omori T, Takagi T, Matsumoto S, Nagasaka M, Sagami S, Kitamura K, Katsurada T, Sugimoto K, Takatsu N, Saruta M, Sakurai T, Watanabe K, Nakamura S, Suzuki Y, Hokari R (2019) Correction to: Management of elderly ulcerative colitis in Japan. J Gastroenterol 54(10):936–937. https://doi.org/10.1007/s00535-019-01606-5

  170. 170.

    Colombo F, Pellino G, Sampietro G, Selvaggi F, Canonico S, Foschi D (2018) Surgical treatment of inflammatory bowel diseases in the elderly. Surgical management of elderly patients. Springer, Cham, pp 191–206

  171. 171.

    Arnott I, Rogler G, Halfvarson J (2018) The management of inflammatory bowel disease in elderly: current evidence and future perspectives. Inflamm Intest Dis 2(4):189–199. https://doi.org/10.1159/000490053

  172. 172.

    Nguyen GC, Du L, Chong RY, Jackson TD (2019) Hypoalbuminaemia and postoperative outcomes in inflammatory bowel disease: the NSQIP surgical Cohort. J Crohn's Colitis. https://doi.org/10.1093/ecco-jcc/jjz083

  173. 173.

    Kedia S, Limdi JK, Ahuja V (2018) Management of inflammatory bowel disease in older persons: evolving paradigms. Intest Res 16(2):194–208. https://doi.org/10.5217/ir.2018.16.2.194

  174. 174.

    Ananthakrishnan AN, Donaldson T, Lasch K, Yajnik V (2017) Management of inflammatory bowel disease in the elderly patient: challenges and opportunities. Inflamm Bowel Dis 23(6):882–893. https://doi.org/10.1097/MIB.0000000000001099

  175. 175.

    Hou JK, Feagins LA, Waljee AK (2016) Characteristics and behavior of elderly-onset inflammatory bowel disease: a multi-center US study. Inflamm Bowel Dis 22(9):2200–2205. https://doi.org/10.1097/MIB.0000000000000849

  176. 176.

    Afzali A, Katz S (2018) Inflammatory bowel disease in the baby to baby boomer: pediatric and elderly onset of IBD. Curr Treat Options Gastroenterol 16(3):289–305. https://doi.org/10.1007/s11938-018-0188-9

  177. 177.

    Sturm A, Maaser C, Mendall M, Karagiannis D, Karatzas P, Ipenburg N, Sebastian S, Rizzello F, Limdi J, Katsanos K, Schmidt C, Jeuring S, Colombo F, Gionchetti P (2017) European Crohn's and colitis organisation topical review on IBD in the elderly. J Crohn's Colitis 11(3):263–273. https://doi.org/10.1093/ecco-jcc/jjw188

  178. 178.

    Gisbert JP, Chaparro M (2014) Systematic review with meta-analysis: inflammatory bowel disease in the elderly. Aliment Pharmacol Ther 39(5):459–477. https://doi.org/10.1111/apt.12616

  179. 179.

    Pellino G, Sciaudone G, Candilio G, Camerlingo A, Marcellinaro R, Rocco F, De Fatico S, Canonico S, Selvaggi F (2013) Complications and functional outcomes of restorative proctocolectomy for ulcerative colitis in the elderly. BMC Surg 13:S9. https://doi.org/10.1186/1471-2482-13-S2-S9

  180. 180.

    Nguyen GC, Bernstein CN, Benchimol EI (2017) Risk of surgery and mortality in elderly-onset inflammatory bowel disease: a population-based cohort study. Inflamm Bowel Dis 23(2):218–223. https://doi.org/10.1097/MIB.0000000000000993

  181. 181.

    Colombo PL, Tinozzi FP, Abelli M, Laera MR, Testone G, Moglia P, Albertario S, Morone G, Bianchi C, Tinozzi S (2002) Aspects of the complications after restorative proctocolectomy in the treatment of ulcerative colitis: review of the literature and personal experience. Ann Ital Chir 73(2):161–171 (discussion 171–162)

  182. 182.

    Williet N, Sarter H, Gower-Rousseau C, Adrianjafy C, Olympie A, Buisson A, Beaugerie L, Peyrin-Biroulet L (2017) Patient-reported outcomes in a French nationwide survey of inflammatory bowel disease patients. J Crohn's Colitis 11(2):165–174. https://doi.org/10.1093/ecco-jcc/jjw145

  183. 183.

    Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, Benchimol EI, Panaccione R, Ghosh S, Barkema HW, Kaplan GG (2012) Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142(1):46–54. https://doi.org/10.1053/j.gastro.2011.10.001(quiz e30)

  184. 184.

    Jackson BD, Gray K, Knowles SR, De Cruz P (2016) EHealth technologies in inflammatory bowel disease: a systematic review. J Crohn's Colitis 10(9):1103–1121. https://doi.org/10.1093/ecco-jcc/jjw059

  185. 185.

    Restellini S, Chao CY, Martel M, Barkun A, Kherad O, Seidman E, Wild G, Bitton A, Afif W, Bessissow T, Lakatos PL (2019) Clinical parameters correlate with endoscopic activity of ulcerative colitis: a systematic review. Clin Gastroenterol Hepatol 17(7):1265–1275.e1268. https://doi.org/10.1016/j.cgh.2018.12.021

  186. 186.

    Khanna R, Zou G, D'Haens G, Feagan BG, Sandborn WJ, Vandervoort MK, Rolleri RL, Bortey E, Paterson C, Forbes WP, Levesque BG (2015) A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn's disease activity. Aliment Pharmacol Ther 41(1):77–86. https://doi.org/10.1111/apt.13001

  187. 187.

    Chung AE, Sandler RS, Long MD, Ahrens S, Burris JL, Martin CF, Anton K, Robb A, Caruso TP, Jaeger EL, Chen W, Clark M, Myers K, Dobes A, Kappelman MD (2016) Harnessing person-generated health data to accelerate patient-centered outcomes research: the Crohn's and Colitis Foundation of America PCORnet Patient Powered Research Network (CCFA Partners). J Am Med Inform Assoc 23(3):485–490. https://doi.org/10.1093/jamia/ocv191

  188. 188.

    Armstrong MJ, Bloom JA (2017) Patient involvement in guidelines is poor five years after institute of medicine standards: review of guideline methodologies. Res Involv Engagem 3:19. https://doi.org/10.1186/s40900-017-0070-2

  189. 189.

    Kirwan JR, de Wit M, Frank L, Haywood KL, Salek S, Brace-McDonnell S, Lyddiatt A, Barbic SP, Alonso J, Guillemin F, Bartlett SJ (2017) Emerging guidelines for patient engagement in research. Value Health 20(3):481–486. https://doi.org/10.1016/j.jval.2016.10.003

  190. 190.

    van de Bovenkamp HM, Zuiderent-Jerak T (2015) An empirical study of patient participation in guideline development: exploring the potential for articulating patient knowledge in evidence-based epistemic settings. Health Expect 18(5):942–955. https://doi.org/10.1111/hex.12067

  191. 191.

    Morar PS, Hollingshead J, Bemelman W, Sevdalis N, Pinkney T, Wilson G, Dunlop M, Davies RJ, Guy R, Fearnhead N, Brown S, Warusavitarne J, Edwards C, Faiz O (2017) Establishing key performance indicators [kpis] and their importance for the surgical management of inflammatory bowel disease-results from a Pan–European, Delphi Consensus Study. J Crohn's Colitis 11(11):1362–1368. https://doi.org/10.1093/ecco-jcc/jjx099

  192. 192.

    Egberg MD, Galanko JA, Kappelman MD (2019) Patients who undergo colectomy for pediatric ulcerative colitis at low-volume hospitals have more complications. Clin Gastroenterol Hepatol. https://doi.org/10.1016/j.cgh.2019.03.003

  193. 193.

    Raval MJ, Schnitzler M, O'Connor BI, Cohen Z, McLeod RS (2007) Improved outcome due to increased experience and individualized management of leaks after ileal pouch–anal anastomosis. Ann Surg 246(5):763–770. https://doi.org/10.1097/SLA.0b013e31814539b1

  194. 194.

    Bemelman WA, Collaborators S-E (2018) Evolving role of IBD surgery. J Crohn's Colitis 12(8):1005–1007. https://doi.org/10.1093/ecco-jcc/jjy056

  195. 195.

    Bemelman WA, Warusavitarne J, Sampietro GM, Serclova Z, Zmora O, Luglio G, de Buck-van-Overstraeten A, Burke JP, Buskens CJ, Colombo F, Dias JA, Eliakim R, Elosua T, Gecim IE, Kolacek S, Kierkus J, Kolho KL, Lefevre JH, Millan M, Panis Y, Pinkney T, Russell RK, Shwaartz C, Vaizey C, Yassin N, D'Hoore A (2018) ECCO-ESCP consensus on surgery for Crohn's disease. J Crohn's Colitis 12(1):1–16. https://doi.org/10.1093/ecco-jcc/jjx061

  196. 196.

    Law CC, Sasidharan S, Rodrigues R, Nguyen DD, Sauk J, Garber J, Giallourakis C, Xavier R, Khalili H, Yajnik V, Ananthakrishnan AN (2016) Impact of specialized inpatient IBD care on outcomes of IBD hospitalizations: a cohort study. Inflamm Bowel Dis 22(9):2149–2157. https://doi.org/10.1097/MIB.0000000000000870

  197. 197.

    Bitton A, Dobkin PL, Edwardes MD, Sewitch MJ, Meddings JB, Rawal S, Cohen A, Vermeire S, Dufresne L, Franchimont D, Wild GE (2008) Predicting relapse in Crohn's disease: a biopsychosocial model. Gut 57(10):1386–1392. https://doi.org/10.1136/gut.2007.134817

  198. 198.

    Bitton A, Vutcovici M, Lytvyak E, Kachan N, Bressler B, Jones J, Lakatos PL, Sewitch M, El-Matary W, Melmed G, Nguyen G, Group Qc, program, PAaCtCoE-P (2019) Selection of Quality Indicators in IBD: integrating physician and patient perspectives. Inflamm Bowel Dis 25(2):403–409. https://doi.org/10.1093/ibd/izy259

  199. 199.

    Holder-Murray J, Marsicovetere P, Holubar SD (2015) Minimally invasive surgery for inflammatory bowel disease. Inflamm Bowel Dis 21(6):1443–1458. https://doi.org/10.1097/MIB.0000000000000316

  200. 200.

    Maggiori L, Khayat A, Treton X, Bouhnik Y, Vicaut E, Panis Y (2014) Laparoscopic approach for inflammatory bowel disease is a real alternative to open surgery: an experience with 574 consecutive patients. Ann Surg 260(2):305–310. https://doi.org/10.1097/SLA.0000000000000534

  201. 201.

    Mackenzie H, Miskovic D, Ni M, Parvaiz A, Acheson AG, Jenkins JT, Griffith J, Coleman MG, Hanna GB (2013) Clinical and educational proficiency gain of supervised laparoscopic colorectal surgical trainees. Surg Endosc 27(8):2704–2711. https://doi.org/10.1007/s00464-013-2806-x

  202. 202.

    Celentano V, Finch D, Forster L, Robinson JM, Griffith JP (2015) Safety of supervised trainee-performed laparoscopic surgery for inflammatory bowel disease. Int J Colorectal Dis 30(5):639–644. https://doi.org/10.1007/s00384-015-2147-4

  203. 203.

    Celentano V, Flashman KG (2019) Stepwise training in laparoscopic surgery for complex ileocolonic Crohn's disease: analysis of 127 training episodes. J Surg Educ 76(5):1364–1369. https://doi.org/10.1016/j.jsurg.2019.03.009

  204. 204.

    Pellino G, Selvaggi F, Ghezzi G, Corona D, Riegler G, Delaini GG (2015) A think tank of the Italian Society of Colorectal Surgery (SICCR) on the surgical treatment of inflammatory bowel disease using the Delphi method: Crohn's disease. Tech Coloproctol 19(10):639–651. https://doi.org/10.1007/s10151-015-1368-4

  205. 205.

    Selvaggi F, Pellino G, Ghezzi G, Corona D, Riegler G, Delaini GG (2015) A think tank of the Italian Society of Colorectal Surgery (SICCR) on the surgical treatment of inflammatory bowel disease using the Delphi method: ulcerative colitis. Tech Coloproctol 19(10):627–638. https://doi.org/10.1007/s10151-015-1367-5

  206. 206.

    Gajendran M, Loganathan P, Catinella AP, Hashash JG (2018) A comprehensive review and update on Crohn's disease. Dis Mon 64(2):20–57. https://doi.org/10.1016/j.disamonth.2017.07.001

  207. 207.

    Romeo E, Jasonni V, Caldaro T, Barabino A, Mattioli G, Vignola S, di Abriola GF, De Angelis P, Pane A, Torroni F, Rea F, Dall'Oglio L (2012) Strictureplasty and intestinal resection: different options in complicated pediatric-onset Crohn disease. J Pediatr Surg 47(5):944–948. https://doi.org/10.1016/j.jpedsurg.2012.01.054

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Acknowledgements

The authors would like to thank Ms. Marina Fiorino, secretary of the SICCR, for her help during the development of the project. The authors and SICCR are grateful to Salvatore Leone for participating on behalf of the “Associazione nazionale per le Malattie Infiammatorie Croniche dell’Intestino” (Italian National Association for Inflammatory Bowel Diseases) “A.M.I.C.I. Onlus” as patient representative in project designing and delivering.

Collaborators: Remo Andreoli, Imerio Angriman, Paola Caprino, Mattia Facchetti, Gaetano Luglio, Gilberto Poggioli, Gianluca Rizzo, Giulia Roda, Matteo Rottoli, Franco Sacchetti, Bruno Sensi, Luigi Sofo.

Steering Committee: Gianluca Pellino (coordinator), Deborah S. Keller (external advisor), Gianluca M. Sampietro (coordinator), Salvatore Leone (patient representative), Silvio Danese (external expert), Antonino Spinelli (leader), GianGaetano Delaini (SICCR IBD Committee Chair, leader), Francesco Selvaggi (SICCR President, leader).

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Correspondence to G. Pellino.

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Informed consent was not needed for this study. No procedures on patients were performed by the authors for this study.

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List of members for The Italian Society of Colorectal Surgery SICCR are given in acknowledgement section.

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Pellino, G., Keller, D.S., Sampietro, G.M. et al. Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management. Tech Coloproctol 24, 105–126 (2020). https://doi.org/10.1007/s10151-019-02145-0

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Keywords

  • Inflammatory bowel disease
  • Crohn’s disease
  • Ulcerative colitis
  • Inflammatory bowel diseases
  • Surgery
  • Pouch