Abstract
Background
The aim of this study was to perform an external validation of Cleveland Clinic Foundation colorectal cancer model in a single center.
Methods
Relevant data of 771 patients who underwent surgery for colorectal cancer between January 1997 and November 2008 were retrospectively collected. The performance of the scoring system was evaluated by discrimination and calibration. Discrimination was evaluated by using the area under the receiver operator characteristics curve and calibration by using the Hosmer–Lemeshow goodness-of-fit test.
Results
Mean age was 60.8 (18–91). Forty-four percent of patients were female, and 56% were male. Overall mortality was 3.9%. Cleveland Clinic Foundation colorectal cancer model showed good discrimination but poor calibration.
Conclusion
These data suggest that the Cleveland Clinic Foundation colorectal cancer model is a suitable model to be used in our center for patients with colorectal cancer but requires recalibration.
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Acknowledgments
The authors thank all of the consultants who contributed patients to this study and Mutlu Hayran (Department of Preventive Oncology, Hacettepe University) for statistical review.
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Dogrul, A.B., Kılıç, Y.A., Celebi, A.E. et al. External validation of Cleveland Clinic Foundation colorectal cancer model in a University Clinic in terms of predicting operative mortality. Tech Coloproctol 14, 9–12 (2010). https://doi.org/10.1007/s10151-009-0546-7
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DOI: https://doi.org/10.1007/s10151-009-0546-7