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International Journal of Clinical Oncology

, Volume 24, Issue 1, pp 87–93 | Cite as

Does tumour effraction during robotic partial nephrectomy have any impact on recurrence?

  • Zine-Eddine KheneEmail author
  • Benoit Peyronnet
  • Benjamin Pradère
  • Corentin Robert
  • Anna Goujon
  • Solène-Florence Kammerer-Jacquet
  • Grégory Verhoest
  • Nathalie Rioux-Leclercq
  • Romain Mathieu
  • Karim Bensalah
Original Article
  • 40 Downloads

Abstract

Objective

To evaluate the impact of accidental surgical incision into the tumour (ASIT) on oncological outcomes in patients undergoing RPN for a malignant tumour.

Materials and methods

A retrospective review of our prospectively maintained database was performed to identify all patients who underwent RPN for a localized RCC between June 2010 and July 2016. We stratified our cohort into two groups according to the presence of an ASIT. Perioperative data were compared between the two groups. Logistic regression analyses were used to assess the variables associated with ASIT. Recurrence-free survival was estimated using the Kaplan–Meier method and compared between groups with the log-rank test.

Results

A total of 234 patients were identified. 32 (14%) ASIT were observed. Patients’ characteristics were similar in the two groups. Most of intraoperative outcomes were comparable between the two groups, but patients in the ASIT group had greater EBL (475 vs. 300 mL; p = 0.01). In multivariate analysis, tumour size (p = 0.02), RENAL score (p = 0.02), EBL (p = 0.05) and low surgeon experience (p = 0.03) were all predictive factors of ASIT. 15 (6%) of recurrences were observed over a median follow-up of 36 months. There was no difference in recurrence-free survival between the two groups (p = 0.57).

Conclusions

In our experience, accidental surgical incision into the tumour during RPN was a common event that did not appear to compromise oncological outcome.

Keywords

Partial nephrectomy Robotic surgical procedures Recurrence Complications Survival 

Notes

Compliance with ethical standards

Conflict of interest

The author declares that there is no competing interest.

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Copyright information

© Japan Society of Clinical Oncology 2018

Authors and Affiliations

  • Zine-Eddine Khene
    • 1
    Email author
  • Benoit Peyronnet
    • 1
  • Benjamin Pradère
    • 1
  • Corentin Robert
    • 2
  • Anna Goujon
    • 1
  • Solène-Florence Kammerer-Jacquet
    • 3
  • Grégory Verhoest
    • 1
  • Nathalie Rioux-Leclercq
    • 3
  • Romain Mathieu
    • 1
  • Karim Bensalah
    • 1
  1. 1.Department of UrologyRennes University HospitalRennes CedexFrance
  2. 2.Department of RadiologyRennes University HospitalRennesFrance
  3. 3.Department of PathologyRennes University HospitalRennesFrance

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