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Efficacy and safety of diode laser during circumvestibular incision for Le Fort I osteotomy in orthognathic surgery: a triple-blind randomized clinical trial

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The aim of this triple-blind randomized clinical trial was to evaluate the efficacy and safety of diode laser during circumvestibular incisions for Le Fort I osteotomy in orthognathic surgeries in comparison with conventional techniques using electrocautery and scalpel. Patients were randomly allocated to one of three groups based on the technique employed to perform incisions: diode laser, electrocautery, and scalpel. The parameters used to evaluate the efficacy and safety of diode laser were incision velocity, duration of surgery, bleeding rate, alterations in postoperative functions, pain, edema, wound clinical healing, and infection. Thirty patients were enrolled in the study (10 per group). Regarding bleeding, the incisions performed with diode laser promoted a lower bleeding rate compared with scalpel and electrocautery (p = 0.00). The diode surgical laser was effective during the incision procedure, but required a longer time to perform the incisions compared with the other techniques evaluated (p < 0.05). No statistically significant difference was detected between groups regarding total surgical time or other safety parameters (p > 0.05). Thus, diode laser proved to be effective and safer during circumvestibular incisions for Le Fort I osteotomy than conventional devices.

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This study was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Finance Code 001), Brazil, and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, #309322/2015-4), Brazil. R.A.M. is a CNPq research fellow. J.A.A.A. is the recipient of fellowships. Mrs. E. Greene provided English editing of the manuscript.

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Correspondence to José Alcides Almeida de Arruda.

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The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the human research Ethics Committee of the study institution (no. 53476816.9.0000.5149).

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Jaeger, F., Chiavaioli, G.M.d., de Toledo, G.L. et al. Efficacy and safety of diode laser during circumvestibular incision for Le Fort I osteotomy in orthognathic surgery: a triple-blind randomized clinical trial. Lasers Med Sci 35, 395–402 (2020). https://doi.org/10.1007/s10103-019-02832-2

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  • Orthognathic surgery
  • Diode laser
  • High-power laser
  • Clinical trial