Methodological correctness of a recent publication on pain entitled “Evaluating the effect of photobiomodulation with a 940-nm diode laser on post-operative pain in periodontal flap surgery”
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I read with great interest the excellent study of Heidari et al. , which was concerned with the efficacy of photobiomodulation in alleviating pain after periodontal surgery. It was a nice split-mouth randomized clinical trial with numerous advantages.
I would appreciate if the authors can explain how this particular sample size had been determined.
The current design looked like a repeated-measures design. So, it would be appropriate to use a repeated-measures ANOVA (or a similar test) instead of paired t tests. If it is not possible to conduct an RM-ANOVA now (for example, lack of raw data), at least, the multiple comparison problems should be addressed using methods such as the Bonferroni correction, i.e., by reducing the level of significance from 0.05 to 0.007, and considering any P values above 0.007 as non-significant.
If the level of significance is to be adjusted to 0.007, it would be needed for the P...
Source of funding
The study was self-funded by the author.
Compliance with ethical standards
Conflict of interest
The author declares that he has no conflict of interest.
- 6.Mohan RR, Doraswamy DC, Hussain AM, Gundannavar G, Subbaiah SK, Jayaprakash D (2014) Evaluation of the role of antibiotics in preventing postoperative complication after routine periodontal surgery: a comparative clinical study. J Indian Soc Periodontol 18(2):205–212. https://doi.org/10.4103/0972-124X.131327 CrossRefGoogle Scholar