Advertisement

The skin rejuvenation associated treatment—Fraxel laser, Microbotox, and low G prime hyaluronic acid: preliminary results

  • Dario Bertossi
  • Giorgio GiampaoliEmail author
  • Alessandra Lucchese
  • Maurizio Manuelli
  • Massimo Albanese
  • Riccardo Nocini
  • Pier Francesco Nocini
Original Article

Abstract

Minimally invasive facial rejuvenation procedures reached an all-time high in the 2016. This reveals a growing interest in a smoother, younger, and tighter look accessible using the esthetic medicine tools like botulinum toxin and dermal filler injections, laser, and microdermabrasion. Forty-five patients from 35 to 52 years old (medium age 43.8), 38 women and 7 men underwent 5 sessions of Fraxel laser, 1 session of very low G prime HA, and Microbotox injection treatments from January 2016 and January 2017, were included in this study. In this study, we demonstrated that the usage of three treatments together, like mBTX, Volite, and Fractional laser, have a better result despite every single technique alone. The clinical result showed 98% (44 patients, 6 males, 38 females) of the patients had a smoother skin surface, brighter, more hydrated, and elastic skin; 68% of our patients (31 patients, 5 males, 26 females) showed less skin defects and staining as well as less small wrinkles, thanks to Fraxel laser treatment; 98% (44 patients, 6 males, 38 females) showed tighter skin with less sebaceous gland secretion. The aim of this study was to demonstrate that the combination of three techniques acts better and faster than single treatment to contrast facial aging and to improve skin texture and quality.

Keywords

Fraxel Microbotox Very low G prime hyaluronic acid 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

References

  1. 1.
    Bertossi D, Albanese M, Turra M, Favero V, Nocini P, Lucchese A (2013) Combined rhinoplasty and genioplasty: long-term follow-up. JAMA Facial Plast Surg 15(3):192–197CrossRefGoogle Scholar
  2. 2.
    Lucchese A, Manuelli M, Bassani L, Albertini P, Matarese G, Perillo L et al (2015) Fiber reinforced composites orthodontic retainers. Minerva Stomatol 64(6):323–333Google Scholar
  3. 3.
    Bertossi D, Lucchese A, Albanese M, Turra M, Faccioni F, Nocini P et al (2013) Piezosurgery versus conventional osteotomy in orthognatic surgery: a paradigm shift in treatment. J Craniofac Surg 24(5):1763–1766CrossRefGoogle Scholar
  4. 4.
    Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC (2012) Skin anti-aging strategies. Dermatoendocrinology 4(3):308–319CrossRefGoogle Scholar
  5. 5.
    Wu WT (2015) Microbotox of the lower face and neck: evolution of a personal technique and its clinical effects. Plast Reconstr Surg 136(5 Suppl):92S–100SCrossRefGoogle Scholar
  6. 6.
    Walgrave S, Zelickson B, Childs J, Altshuler G, Erofeev A, Yaroslavsky I, Kist D, Counters J (2008) Pilot investigation of the correlation between histological and clinical effects of infrared fractional resurfacing lasers. Dermatol Surg 34(11):1443–1453Google Scholar
  7. 7.
    Fabi S, Pavicic T, Braz A, Green JB, Seo K, van Loghem JA (2017) Combined aesthetic interventions for prevention of facial ageing, and restoration and beautification of face and body. Clin Cosmet Investig Dermatol 10:423–429CrossRefPubMedCentralGoogle Scholar
  8. 8.
    Bertossi D, Mortellaro C, Nocini P (2016) New clinical analysis and device for Botox injections. J Craniofac Surg 27(6):1554–1557CrossRefGoogle Scholar
  9. 9.
    Cohen SR, Goodacre A, Lim S, Johnston J, Henssler C, Jeffers B, Saad A, Leong T (2017) Clinical outcomes and complications associated with fractional lasers: a review of 730Patients. Aesthet Plast Surg 41(1):171–178CrossRefGoogle Scholar
  10. 10.
    Pham AM, Greene RM, Woolery-Lloyd H, Kaufman J, Grunebaum LD (2011) 1550-nm nonablative laser resurfacing for facial surgical scars. Arch Facial Plast Surg 13(3):203–210CrossRefGoogle Scholar
  11. 11.
    Bertossi D, Tessari G, Girolomoni G, Nocini PF (2016) The facial grid analysis for filler injection: a cohort study of 300 patients. G Ital Dermatol Venereol 151(5):467–472Google Scholar
  12. 12.
    Monheit G (2015) Neurotoxins: current concepts in cosmetic use on the face and neck--upper face (glabella, forehead, and Crow’s feet). Plast Reconstr Surg 136(5 Suppl):72S–75SCrossRefGoogle Scholar
  13. 13.
    Raspaldo H, Baspeyras M, Bellity P, Dallara JM, Gassia V, Niforos FR, Belhaouari L (2011) Upper- and mid-face anti-aging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 1. Consensus Group. J Cosmet Dermatol 10(1):36–50CrossRefGoogle Scholar
  14. 14.
    Kwon HH, Park HY, Choi SC, Bae Y, Kang C, Jung JY, Park GH (2017) Combined fractional treatment of acne scars involving non-ablative 1,550-nm erbium-glass laser and micro-needling radiofrequency: a 16 week prospective, randomized Split-faceStudy. Acta Derm Venereol 97(8):947–951CrossRefGoogle Scholar
  15. 15.
    Bencini PL, Tourlaki A, Galimberti M, Pellacani G (2015) Non-ablative fractionated laser skin resurfacing for the treatment of aged neck skin. J Dermatol Treat 26(3):252–256CrossRefGoogle Scholar
  16. 16.
    Raspaldo H, Niforos FR, Gassia V, Dallara JM, Bellity P, Baspeyras M, Belhaouari L (2011) Lower-face and neck antiaging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 2. Consensus Group. J Cosmet Dermatol 10(2):131–149CrossRefGoogle Scholar
  17. 17.
    Lucchese A, Matarese G, Ghislanzoni LH, Gastaldi G, Manuelli M, Gherlone E (2016) Efficacy and effects of palifermin for the treatment of oral mucositis in patients affected by acute lymphoblastic leukemia. Leuk Lymphoma 57(4):820–827CrossRefGoogle Scholar
  18. 18.
    Lucchese A, Matarese G, Manuelli M, Ciuffreda C, Bassani L, Isola G et al (2016) Reliability and efficacy of palifermin in prevention and management of oral mucositis in patients with acute lymphoblastic leukemia: a randomized, double-blind controlled clinical trial. Minerva Stomatol 65(1):43–50Google Scholar
  19. 19.
    Manuelli M (2012) On line is the future. Prog Orthod 13(3):201CrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Ltd., part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Oral and Maxillofacial SurgeryUniversity of VeronaVeronaItaly
  2. 2.Department of OrthodonticsVita-Salute San Raffaele UniversityMilanItaly
  3. 3.Unit of Dentistry, Division of Orthodontics, Research area in Dentofacial Orthopedics and OrthodonticsIRCCS San Raffaele Scientific InstituteMilanItaly
  4. 4.ENT DepartmentUniversity of VeronaVeronaItaly

Personalised recommendations