Listeria monocytogenes detected in vaginal self-samples of 2 women after spontaneous miscarriage, Senegal, West Africa
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Listeriosis is an infectious disease that causes high morbidity and mortality, particularly in developing countries . The global burden of this disease was estimated at more than 20,000 illnesses, approximately 5500 deaths and more than 172,000 disability-adjusted life years in 2010 . More recently, in South Africa in 2017–2018, more than 1000 cases and at least 193 deaths were reported (with 28% mortality among cases with known outcomes ). The transmission of this pathogen is a major public health issue, and its control is needed to reduce child mortality and improve maternal health . Perinatal listeriosis accounts for approximately 20% of all cases and has been associated with amnionitis, leading to respiratory symptoms, meningitis, and death among newborns. Placental Listeria monocytogenes infection has been well documented [1, 2, 3, 4, 5], but L. monocytogenes has been only occasionally detected in vaginal samples of women suffering from spontaneous miscarriage [4, 5]....
This work benefited from the support by the French State, managed by the Agence Nationale pour la Recherche, including the “Programme d’Investissements d’avenir” under the reference Méditerranée Infection 10-IAHU-03. This work was also supported by the région Provence-Alpes-Côte d’Azur and European funding from FEDER PRIMI.
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