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Role of prolonged blood culture incubation in infective endocarditis diagnosis

  • Madiha Fida
  • Brenda L. Dylla
  • M. Rizwan Sohail
  • Bobbi S. Pritt
  • Audrey N. Schuetz
  • Robin Patel
Letter to the Editor

We read with interest the recent publication by Lindell et al. describing a large cohort of Cutibacterium/Propionibacterium prosthetic valve endocarditis (PVE) [1]. Cutibacterium/Propioniobacterium species are facultative anaerobes which are part of the normal skin microbiota and are increasingly recognized as a cause of endovascular infection, in recent reports, constituting 3.8–8% of PVE cases [1, 2]. As slow-growing organisms, Cutibacterium/Propionibacteriumspecies may require prolonged durations of incubation for isolation. Accordingly, they may be missed with conventional durations of blood culture incubation. Prolonged blood culture incubation is frequently requested by the Infectious Diseases clinicians at our institution in cases of suspected endocarditis; however, the clinical value of this practice has been incompletely defined. Likewise, the clinical value of blind subcultures and terminal Gram or acridine orange staining of negative blood culture bottles in such...

References

  1. 1.
    Lindell F et al (2018) Prosthetic valve endocarditis caused by Propionibacterium species: a national registry-based study of 51 Swedish cases. Eur J Clin Microbiol Infect Dis 37(4):765–771CrossRefGoogle Scholar
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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Infectious Diseases, Department of Internal MedicineMayo ClinicRochesterUSA
  2. 2.Division of Clinical Microbiology, Department of Laboratory Medicine and PathologyMayo ClinicRochesterUSA

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