Exploring the role of music therapy in multiple sclerosis: brief updates from research to clinical practice

  • Claudia VinciguerraEmail author
  • Nicola De Stefano
  • Antonio Federico
Review Article



Physical, cognitive and mood-behavioral disturbances are very common in people with multiple sclerosis (MS) representing a relevant disease burden. Recently, in this field, several studies investigated the role of music therapy (MT) as a complementary therapeutic approach especially in terms of rehabilitation strategy.


The aim of this review is to report and discuss the effectiveness of various music-based interventions (MBIs) for clinical outcomes in MS patients.

Data sources

All English medical papers registered in the Web of Knowledge, PubMed, Google Scholar, and ScienceDirect from March 1999 to March 2019.

Inclusion and exclusion criteria

We selected all the articles concerning MBIs in MS including papers that dealt with human samples and excluding non-human samples, reviews and case reports.


Out of 46 articles, we selected 24 papers of which 13 completely following the inclusion criteria were evaluated for the present analysis.


We explored the efficacy of several MT programs, taking into account the different aspects of application feasibility in the clinical management of MS patients and the future challenges.


Multiple sclerosis (MS) Music-based interventions (MBIs) Music therapy (MT) 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  1. 1.Department of Medicine, Surgery and NeurosciencesUniversity of SienaSienaItaly

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