Neurorehabilitation: bridging neurophysiology and clinical practice
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Sensorimotor impairment of upper limb (UL) movements after stroke persists over time in a large proportion of patients. At 6 months post-stroke, 50–70% of patients continue to have UL impairments. The most common deficits of the UL are paresis and spasticity leading to residual functional deficits. These impairments affect the ability to perform functional tasks and lead to decreased quality of life and participation .
The focus of early acute stroke management (i.e., 72 h post-stroke) is on stabilizing the medical condition of the patient [2, 3]. In the post-acute stage (i.e., < 3 months after stroke), the focus shifts to neurorehabilitation that may include exercise combined with technology such as robot-assisted training  or neuromuscular electrical stimulation for UL rehabilitation  that has been shown to play a key role in functional recovery. Clinical trials aiming at enhancing training-based neuroplasticity have incorporated different principles...
The author is grateful to Mindy F. Levin for her valued comments and suggestions.
DP is supported by the Fonds de la Recherche du Québec en Santé (FRQS).
Compliance with ethical standards
Conflict of interest
The author declares that he has no conflict of interest.
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