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Neurological Sciences

, Volume 40, Issue 10, pp 2193–2195 | Cite as

Idiopathic hypertrophic cranial pachymeningitis as a rare cause of status epilepticus

  • Monica MargoniEmail author
  • Mattia Barbareschi
  • Umberto Rozzanigo
  • Silvio Sarubbo
  • Franco Chioffi
  • Raffaella Tanel
Letter to the Editor
  • 60 Downloads

Dear Editor,

Hypertrophic cranial pachymeningitis (HCPM) is characterized by marked diffuse thickening of the cranial dura mater. Several clinico-pathological entities determinate thickening of the pachymeninges (i.e., infectious, neoplastic, or autoimmune disorders). Despite the evaluation for the causes of the HCPM, there are numerous cases without cause, termed idiopathic hypertrophic cranial pachymeningitis (IHCPM). IHCPM is a diagnosis of exclusion and a meningeal biopsy is essential to rule out known causes [1].

The main clinical symptoms at IHCPM onset consist of headache or cranial nerve palsies caused by compression of anatomic structures due to the abnormally thickened dura [2]. Even though seizures are an uncommon manifestation of IHCPM, we describe two cases that highlight the importance of this condition as a possible cause of status epilepticus.

Case presentation

Case 1

A 30-year-old man presented to the emergency room for sensory aphasia. The patient’s medical history...

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the local ethics committee according to the IV revision of declaration of Helsinki.

Consent

This is a descriptive, observational study in which the identity of the patient is completely protected; therefore, no informed consent is required.

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Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  1. 1.Department of Neurosciences DNSUniversity Hospital of PadovaPaduaItaly
  2. 2.Padova Neuroscience Center (PNC)PaduaItaly
  3. 3.Department of HistopathologySanta Chiara HospitalTrentoItaly
  4. 4.Department of RadiologySanta Chiara HospitalTrentoItaly
  5. 5.Division of Neurosurgery, Department of NeurosciencesSanta Chiara HospitalTrentoItaly
  6. 6.Structural and Functional Connectivity Lab, Division of NeurosurgerySanta Chiara HospitalTrentoItaly
  7. 7.Division of Neurology, Department of NeurosciencesSanta Chiara HospitalTrentoItaly

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