Idiopathic hypertrophic cranial pachymeningitis as a rare cause of status epilepticus
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Hypertrophic cranial pachymeningitis (HCPM) is characterized by marked diffuse thickening of the cranial dura mater. Several clinico-pathological entities determinate thickening of the pachymeninges (i.e., infectious, neoplastic, or autoimmune disorders). Despite the evaluation for the causes of the HCPM, there are numerous cases without cause, termed idiopathic hypertrophic cranial pachymeningitis (IHCPM). IHCPM is a diagnosis of exclusion and a meningeal biopsy is essential to rule out known causes .
The main clinical symptoms at IHCPM onset consist of headache or cranial nerve palsies caused by compression of anatomic structures due to the abnormally thickened dura . Even though seizures are an uncommon manifestation of IHCPM, we describe two cases that highlight the importance of this condition as a possible cause of status epilepticus.
A 30-year-old man presented to the emergency room for sensory aphasia. The patient’s medical history...
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Conflict of interest
The authors declare that they have no conflict of interest.
The study was approved by the local ethics committee according to the IV revision of declaration of Helsinki.
This is a descriptive, observational study in which the identity of the patient is completely protected; therefore, no informed consent is required.
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