Ischemic stroke due to sarcoidosis: the arterial wall enhancement on magnetic resonance imaging
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Sarcoidosis is a multisystem granulomatous disorder that primarily affects the lungs and lymph nodes, followed by the skin, liver, eyes, heart, and musculoskeletal system. Symptomatic neurological manifestation occurs only in approximately 5% of sarcoidosis patients, including cranial mononeuropathy, intracranial or spinal cord mass, hydrocephalus, limb peripheral neuropathy, and stroke [1, 2, 3]. Although stroke is a rare complication, in the pathological studies, sarcoid granulomas tend to affect the leptomeninges, Virchow–Robin perivascular spaces, and adventitia of cerebral arteries with occasional invasions to the media and intima . The damage to the vasculatures provokes ischemic and hemorrhagic strokes. In particular, ischemic stroke has become increasingly detectable with the advent of diffusion-weighted magnetic resonance imaging (MRI) and the lesion is typically small because sarcoid granulomas preferentially affect small- and medium-sized arteries . Here,...
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The author declares that he has no conflict of interest.
- 5.Mandell DM, Mossa-Basha M, Qiao Y, Hess CP, Hui F, Matouk C, Johnson MH, Daemen MJ, Vossough A, Edjlali M, Saloner D, Ansari SA, Wasserman BA, Mikulis DJ (2017) Intracranial vessel wall MRI: principles and expert consensus recommendations of the American Society of Neuroradiology. AJNR Am J Neuroradiol 38:218–229CrossRefGoogle Scholar