Neurological Sciences

, Volume 40, Issue 4, pp 683–690 | Cite as

The Parkinson fatigue scale: an evaluation of its validity and reliability in Greek Parkinson’s disease patients

  • Ioannis E. DagklisEmail author
  • Efthymia Tsantaki
  • Dimitrios Kazis
  • Varvara Theodoridou
  • Sotirios Papagiannopoulos
  • Dimitrios Ntantos
  • Sevasti Bostantjopoulou
Original Article



Fatigue is one of the most frequent and important nonmotor symptoms of patients with Parkinson disease (PD), affecting quality of life. Although, in some cases, it may be a severe and debilitating complaint, it remains relatively unexplored. The PFS-16 is a fatigue measure, specifically designed for PD patients. The aim of this study was to investigate the psychometric properties of Parkinson fatigue scale (PFS-16) in Greek PD patients.


In total, 99 patients with PD were assessed. The following psychometric properties were tested: data quality, floor/ceiling effects, reliability (internal consistency, test–retest reliability), and construct validity. Construct validity was evaluated by examining correlations with other variables including other fatigue measures such as Fatigue Severity Scale (FSS) and the vitality scale (SF-VT) of SF-36. Moreover, assumptions were explored about “known” groups concerning fatigue.


The mean score for the PFS-16 was 2.95 (± 0.91); acceptability was good with negligible floor and ceiling effects. Results showed high internal consistency (Cronbach’s alpha, 0.96) and test–retest reliability (ICC, 0.93). Strong correlations were observed between the PFS-16 and other fatigue (FFS and SF-VT) measures (rs = 0.77 and − 0.70, p < 0.001), revealing appropriate validity. Furthermore, predictions for “known” groups validity were verified.


The Greek version of the PFS-16 showed satisfactory reliability and validity and thus can be regarded as a useful tool in assessing fatigue in PD.


Fatigue Parkinson fatigue scale Reliability Validity 



We gratefully thank Prof. Brown for his permission to translate and use the PFS-16 in this study and for his useful remarks.


The author(s) received no financial support for the research, authorship, and/or publication of this article.

Compliance with ethical standards

The study was carried out in accordance with the Declaration of Helsinki on Ethical Principles for Medical Research.

Conflicting interests

The authors declare that they have no conflict of interest.


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Copyright information

© Fondazione Società Italiana di Neurologia 2019

Authors and Affiliations

  1. 1.3rd Department of NeurologyAristotle University of Thessaloniki, G. Papanikolaou HospitalThessalonikiGreece
  2. 2.Laboratory of Primary Health Care, General Practice and Health Services Research - Medical SchoolAristotle University of ThessalonikiThessalonikiGreece

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