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Neurological Sciences

, Volume 40, Issue 2, pp 357–362 | Cite as

MR evaluation of encephalic leukoaraiosis in sudden sensorineural hearing loss (SSNHL) patients

  • Franca DicuonzoEmail author
  • Stefano Purciariello
  • Aurora De Marco
  • Dario Dimauro
  • Isabella Laura Simone
  • Francesco Lepore
  • Francesco Paolo Bianchi
  • Nicola Quaranta
Original Article
  • 62 Downloads

Abstract

Epidemiological evidence suggests a strict correlation between sudden sensorineural hearing loss (SSNHL) and cerebrovascular disorders. Leukoaraiosis represents a diffuse alteration of the periventricular and subcortical white matter. The aim of our study was to verify if the presence of white matter hyperintensity (WMH) was higher in patients affected by SSNHL compared to controls and evaluate the correlation between WMH and the cardiovascular risk factors, hearing level, and the response to therapy in SSNHL patients. The study group included 36 subjects affected by unilateral SSNHL. Thirty-six age- and sex-matched normal subjects with a negative history of SSNHL were used as controls. All patients underwent magnetic resonance imaging (MRI) (1.5 Tesla GE Signa) and the extent of leukoaraiosis was assessed with the Fazekas scale. The results of the present study demonstrate a high prevalence of WMH in SSNHL patients compared to controls confirming the hypothesis of a vascular impairment in SSNHL patients. The higher recovery rate in patients with greater periventricular white matter hyperintensity (PWMH) may suggest a vascular etiology that is still responsive to medical treatment. We aim to expand both the number of patients and the controls to avoid the limitation of the still small number to warrant solid scientific conclusions.

Keywords

Sudden sensorineural hearing loss Leukoaraiosis Small vessel disease Magnetic Resonance Periventricular white matter lesions PVWML Recovery rate 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  • Franca Dicuonzo
    • 1
    Email author
  • Stefano Purciariello
    • 1
  • Aurora De Marco
    • 1
  • Dario Dimauro
    • 1
  • Isabella Laura Simone
    • 2
  • Francesco Lepore
    • 3
  • Francesco Paolo Bianchi
    • 4
  • Nicola Quaranta
    • 3
  1. 1.Neuroradiology Unit, Department of Basic Medical Science, Neuroscience and Sense Organs, School of MedicineUniversity of Bari “Aldo Moro”BariItaly
  2. 2.Neurology Unit, Department of Basic Medical Science, Neuroscience and Sense OrgansUniversity of Bari “Aldo Moro”BariItaly
  3. 3.Otolaryngology Unit, Department of Basic Medical Science, Neuroscience and Sense OrgansUniversity of Bari “Aldo Moro”BariItaly
  4. 4.Department of Biomedical Science and Human OncologyUniversity of Bari “Aldo Moro”BariItaly

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