Neurological Sciences

, Volume 39, Issue 12, pp 2213–2216 | Cite as

Parkinsonism and multiple sclerosis, what is behind?

  • Funda Uysal TanEmail author
Letter to the Editor

Dear Editor,

The awareness of the coexistence of both diseases in some patients resulted in an ongoing debate on either causal or coincidental relationship between multiple sclerosis (MS) and parkinsonism [1, 2]. Present data offers some rationale for both theories. In the cases presented in the literature, mostly, Parkinson’s disease (PD) follows the MS [1, 2].

A 43-year-old man complained of tremor of the left arm in 2010. Neurological examination revealed resting tremor of the left upper extremity with mild bradykinesia and mild rigidity, and hypomimia. He had a normal-based gait, with absent left arm swing. The symptoms markedly improved by administration of pramipexole.

In his history, he had mild vertigo, ataxia, and gait disturbances in 2002. Brain magnetic resonance imaging (MRI) revealed demyelinating lesions of the central nervous system consistent with MS: multiple hyperintense lesions located in periventricular areas, the corpus callosum, and the subcortical white matter of...


Compliance with ethical standards

Conflict of interest

The author declares that there is no conflict of interest.

Ethical approval

This article does not contain any studies with human participants performed by any of the authors.

Informed consent

The patient was well informed and permission obtained for report as no identifying personal data is also used in case description.


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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Neurology ClinicMemorial Ankara HospitalAnkaraTurkey

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