A case of normal pressure hydrocephalus presenting as ventriculoperitoneal shunt-responsive dementia and choreodystonia
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Normal pressure hydrocephalus (NPH) is clinically characterized by progressive gait disturbance, dementia, and urinary incontinence, although the manifestations are known to vary. Features of parkinsonism including freezing of gait have been commonly shown in patients with NPH [1, 2], while chorea or dystonia has rarely been reported [2, 3]. We report a case of an elderly female diagnosed with NPH who presented with dementia and mixed movement disorder phenomenology including chorea and dystonia.
A 68-year-old woman was admitted to our hospital for evaluation of progressive gait difficulty and involuntary movements. The patient’s past medical history was notable for hypertension, diabetes mellitus, a stroke involving the right occipital lobe that occurred 3 years prior to this presentation, and osteoarthritis of bilateral knees. The year prior, she was diagnosed with unspecified dementia at an outside institution and was additionally prescribed an acetylcholinesterase inhibitor. Her...
This work was supported by the Soonchunhyang University Research Fund.
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The authors declare that they have no conflict of interest.
Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.
- 4.Hashimoto M, Ishikawa M, Mori E, Kuwana N, Study of INPH on neurological improvement (SINPHONI) (2010) Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study. Cerebrospinal Fluid Res 31:18Google Scholar