Neurological Sciences

, Volume 39, Issue 9, pp 1537–1545 | Cite as

The 100 most-cited articles in Parkinson’s disease

  • Jin-hua Xue
  • Zhi-ping Hu
  • Ping Lai
  • De-qing CaiEmail author
  • Er-sheng WenEmail author
Original Article



Parkinson’s disease (PD), the second most common neurodegenerative disease, has serious clinical effects. Research on PD is increasing, but the quantity and quality of this research have not been reported.


To analyze the most-cited articles on PD and provide information about developments in this field, we searched for articles in the Web of Science for the keyword “Parkinson*” in the title. We selected the 100 most-cited articles and evaluated information including citation number, publication time, journal, impact factor, authors, original country, institution of corresponding author, and study type.


Citation numbers for the 100 most-cited articles ranged from 669 to 6902, with a median of 944. The 100 articles were published from 1967 to 2009, with most appearing between 1996 and 2000 (n = 24) and 2001 to 2005 (n = 27). The publications appeared in a total of 31 journals, led by Science with 15 and the New England Journal of Medicine (NEJM) with 13. The majority (84%) of the 100 most-cited articles had ≥ 3 authors. The articles originated from 14 countries, led by the USA (n = 44) and England (n = 17). Among the 100 most-cited articles, 24 were clinical studies, 54 were laboratory studies, 20 were reviews, and 2 were clinical guidelines. None of these articles originated from South America, Oceania, or Africa.


The present study provides historical perspectives on the progress of PD research and highlights trends and academic achievements in this field.


Most-cited Parkinson’s disease Neurodegenerative diseases 



This work was supported by the Bureau of Education of Jiangxi province (150972, GJJ13686), Health Department of Jiangxi Provincial (20122032). De-qing Cai would like to thank the Health and Family Planning Commission of Jiangxi Province (20175559). We are grateful for the efforts of Yuan-hui Liu, MD, of the Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou 510100, China.

Compliance with ethical standards

Conflict of interest

None declared.

Supplementary material

10072_2018_3450_MOESM1_ESM.docx (33 kb)
ESM 1 Journals with more than one of the top 100 cited articles on Parkinson’s disease (DOCX 32 kb)
10072_2018_3450_MOESM2_ESM.docx (29 kb)
ESM 2 Authors with two or more of the top-100 cited articles on Parkinson’s disease (DOCX 28 kb)
10072_2018_3450_MOESM3_ESM.docx (29 kb)
ESM 3 Institutions with two or more of the top-100 cited articles on Parkinson’s disease (DOCX 29 kb)


  1. 1.
    Lang AE, Lozano AM (1998) Parkinson's disease. Second of two parts. N Engl J Med 339(16):1130–1143CrossRefPubMedGoogle Scholar
  2. 2.
    Lang AE, Lozano AM (1998) Parkinson's disease. First of two parts. N Engl J Med 339(15):1044–1053CrossRefPubMedGoogle Scholar
  3. 3.
    Aarsland D, Larsen JP, Tandberg E, Laake K (2000) Predictors of nursing home placement in Parkinson’s disease: a population-based, prospective study. J Am Geriatr Soc 48:938–942CrossRefPubMedGoogle Scholar
  4. 4.
    Hely MA, Reid WG, Adena MA, Halliday GM, Morris JG (2008) The Sydney multicenter study of Parkinson’s disease: the inevitability of dementia at 20 years. Mov Disord 23:837–844CrossRefPubMedGoogle Scholar
  5. 5.
    Moed HF (2009) New developments in the use of citation analysis in research evaluation. Arch Immunol Ther Exp 57:13–18CrossRefGoogle Scholar
  6. 6.
    Smith DR, Rivett DA (2009) Bibliometrics, impact factors and manual therapy: balancing the science and the art. Man Ther 14:456–459CrossRefPubMedGoogle Scholar
  7. 7.
    Yi F, Ma J, Ni W, Chang R, Liu W, Han X, Pan D, Liu X, Qiu J (2013) The top cited articles on glioma stem cells in Web of Science. Neural Regen Res 8(15):1431–1438PubMedCentralPubMedGoogle Scholar
  8. 8.
    Dolan RS, Hanna TN, Warraich GJ, Johnson JO, Khosa F (2015) The top 100 articles in the radiology of trauma: a bibliometric analysis. Emerg Radiol 22(6):667–675CrossRefPubMedGoogle Scholar
  9. 9.
    Lee S, Shin J, Haro M, Khair M, Riboh JC, Kuhns BD et al (2015) Fifty most cited articles for femoroacetabular impingement and hip arthroscopy. Front Surg 2:41CrossRefPubMedCentralPubMedGoogle Scholar
  10. 10.
    Pagni M, Khan NR, Cohen HL et al (2014) Highly cited works in radiology: the top 100 cited articles in radiologic journals. Acad Radiol 21:1056–1066CrossRefPubMedGoogle Scholar
  11. 11.
    Long X, Huang JZ, Ho YS (2014) A historical review of classic articles in surgery field. Am J Surg 208:841–849CrossRefPubMedGoogle Scholar
  12. 12.
    Lim KJ, Yoon DY, Yun EJ, Seo YL, Baek S, Gu DH, Yoon SJ, Han A, Ku YJ, Kim SS (2012) Characteristics and trends of radiology research: a survey of original articles published in AJR and Radiology between 2001 and 2010. Radiology 264:796–802CrossRefPubMedGoogle Scholar
  13. 13.
    Azer SA, Azer S (2016) Bibliometric analysis of the top-cited gastroenterology and hepatology articles. BMJ Open 6:e009889CrossRefPubMedCentralPubMedGoogle Scholar
  14. 14.
    de Lau LM, Breteler MM (2006) Epidemiology of Parkinson’s disease. Lancet Neurol 5(6):525–535CrossRefPubMedGoogle Scholar
  15. 15.
    Eyre-Walker A, Stoletzki N (2013) The assessment of science: the relative merits of post-publication review, the impact factor, and the number of citations. PLoS Biol 11:e1001675CrossRefPubMedCentralPubMedGoogle Scholar
  16. 16.
    Lariviere V, Gingras Y (2010) The impact factor’ s Matthew effect: a natural experiment in bibliometrics. J Am Soc Inf Sci Tec 61:424–427CrossRefGoogle Scholar
  17. 17.
    Paris G, De Leo G, Menozzi P et al (1998) Region-based citation bias in science. Nature 396:210CrossRefPubMedGoogle Scholar
  18. 18.
    Stephane B (1998) Normative versus social constructivist processes in the allocation of citations: a network-analytic model. Am Sociol Rev 63:829–846CrossRefGoogle Scholar
  19. 19.
    Adam D (2002) The counting house. Nature 415:726–729CrossRefPubMedGoogle Scholar
  20. 20.
    Huang W, Wang L, Wang B, Yu L, Yu X (2016) Top 100 cited articles on back pain research: a citation analysis. Spine 41(21):1683–1692CrossRefPubMedGoogle Scholar
  21. 21.
    Garfield E (2006) The history and meaning of the journal impact factor. JAMA 295:90–93CrossRefPubMedGoogle Scholar
  22. 22.
    Fendrich V, Rothmund M (2010) Surgical research in Germany—an international comparison. Chirurg 81:328–333CrossRefPubMedGoogle Scholar
  23. 23.
    Brookes BC (1969) Bradford’s law and the bibliography of science. Nature 224:953–956CrossRefPubMedGoogle Scholar
  24. 24.
    Tsai YL, Lee CC, Chen SC, Yen ZS (2006) Top-cited articles in emergency medicine. Am J Emerg Med 24:647–654CrossRefPubMedGoogle Scholar
  25. 25.
    Murray MR, Wang T, Schroeder GD, Hsu WK (2012) The 100 most cited spine articles. Eur Spine J 21:2059–2069CrossRefPubMedCentralPubMedGoogle Scholar
  26. 26.
    Shuaib W, Khan MS, Shahid H et al (2015) Bibliometric analysis of the top 100 cited cardiovascular articles. Am J Cardiol 115:972–981CrossRefPubMedGoogle Scholar
  27. 27.
    Link AM (1998) US and non-US submissions: an analysis of reviewer bias. JAMA 280:246–247CrossRefPubMedGoogle Scholar
  28. 28.
    Kulkarni AV, Aziz B, Shams I, Busse JW (2009) Comparisons of citations in Web of Science, Scopus, and Google Scholar for articles published in general medical journals. JAMA 302:1092–1096CrossRefPubMedGoogle Scholar
  29. 29.
    Bakkalbasi N, Bauer K, Glover J, Wang L (2006) Three options for citation tracking: Google Scholar, Scopus and Web of Science. Biomed Digit Libr 3:7CrossRefPubMedCentralPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Physiology, School of Basic Medical SciencesGannan Medical UniversityGanzhouChina
  2. 2.Department of Cardiologythe First Affiliated Hospital of Gannan Medical UniversityGanzhouChina
  3. 3.Department of Library and Information CenterGannan Medical UniversityGanzhouChina

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