BK-virus progressive multifocal leukoencephalitis in a patient with systemic lupus erythematosus
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Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the central nervous system (CNS), fatal in some cases, and JC virus (JCV) is the usual cause .
BK virus (BKV) is a ubiquitous virus and its primary infection is generally asymptomatic. It occurs in childhood  and, as well as JCV, belongs to the Polyomaviridae family. Both viruses are associated with a clinical disease in the setting of immunosuppression: JCV commonly in association with PML, while BKV with nephropathy and hemorrhagic cystitis .
Here we report a rare case of BKV-associated PML in a patient with systemic lupus erythematosus (SLE).
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Conflict of interest
The authors declare that they have no conflict of interest.
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