Neurological Sciences

, Volume 39, Issue 9, pp 1607–1608 | Cite as

Unilateral hyperhidrosis as persistently isolated feature of syringomyelia and Arnold Chiari type 1

  • Claudia StancanelliEmail author
  • Anna Mazzeo
  • Luca Gentile
  • Giuseppe Vita
Letter to the Editor

Dear Editor,

Anhidrosis and hyperhidrosis can be manifestations of irritations of the central or peripheral nervous system and many causes such as injuries, tumors, infarcts, or hemorrhages of the brain or spinal cord have been reported [1]. Unilateral hyperhidrosis is a rare medical event. Differential diagnosis for unilateral hyperhidrosis should include hypothalamic tumor, cerebral infarction, encephalitis, syringomyelia, trauma, neuritis, cervical rib, and intrathoracic malignancy [2].

Here, we report the case of a 22-year-old man who came to our attention because he noticed for 2 years to sweat much more on the left side of his body. When he came to our hospital, he was completely well, having an active working and social life. His family history and his past medical history were negative for any disease. He did not complain of flushing, palpitations, or other symptoms, and he was just referring an excessive sweating on all his left body-side, especially after exertion. His...


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Brodoehl S, Witte OW, Guenther A (2013) Compensatory quadrant hyperhidrosis after contralateral intrathoracic surgery: a case report. J Med Case Rep 7:24CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Waran E (2016) Doctor, I am sweating on just one side of my body: unilateral hyperhidrosis associated with mesothelioma. Clin Case Rep 4(5):533–534CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Casellini CM, Parson HK, Richardson MS, Nevoret ML, Vinik AI (2013) Sudoscan, a noninvasive tool for detecting diabetic small fiber neuropathy and autonomic dysfunction. Diabetes Technol Ther 15(11):948–953CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Sudo K, Fujiki N, Tsuji S, Ajiki M, Higashi T, Niino M, Kikuchi S, Moriwaka F, Tashiro K (1999) Focal (segmental) dyshidrosisin syringomyelia. J Neurol Neurosurg Psychiatry 67(1):106–108CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Tubbs RS, Tyler-Kabara EC, Oakes WJ (2006) Unilateral occipital hyperhidrosis following Chiari I decompression: case report and a review of the literature. Childs Nerv Syst 22(7):737–739CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Biomedical Department of Internal Medicine and SpecialisticUniversity of PalermoPalermoItaly
  2. 2.Department of Clinical and Experimental MedicineUniversity of MessinaMessinaItaly
  3. 3.UOC Neurologia e Malattie Neuromuscolari, AOU Policlinico Gaetano MartinoMessinaItaly

Personalised recommendations