Preparation and characterization of α-tocopherol nanocapsules based on gum Arabic-stabilized nanoemulsions
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The preparation of water dispersed α-tocopherol nanocapsules through solvent-displacement technique using gum Arabic (GA) as natural stabilizing and emulsifying biopolymer, for a first time was aimed in current research. The effects of GA concentrations on physicochemical and biological characteristics of prepared nanocapsules, namely, mean particle size, size distribution, zeta potential, rheological properties, turbidity, in vitro antioxidant activity and cellular uptake were evaluated, subsequently. The result indicated that the mono modal size distributed water dispersible α-tocopherol nanocapsules could be successfully attained using selected technique in sizes ranged from 10.01 to 171.2 nm and zeta potential of − 13.5 to − 47.8 mv. The prepared nanocapsules showed the dilatant rheological properties and acceptable radical scavenging (antioxidant activity). The cellular uptake of samples were increased up to 12 times more than microsized α-tocopherol. Consequently, the prepared water dispersed nanosized α-tocopherol can effectively be used in water based food and beverage formulations as nutrition enhancer or natural preservatives.
Keywordsα-Tocopherol Gum Arabic Nanoencapsulation Nanoemulsions Stabilizer
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- Anarjan N, and Tan C. Physico-chemical stability of astaxanthin nanodispersions prepared with polysaccharides as stabilizing agents. Int. J. Food Sci. Technol. 64: 744–748 (2013a)Google Scholar
- Gomes GVL, Sola MR, Marostegan LFP, Jange CG, Cazado CPS, Pinheiro AC, Vicente AA, Pinho SC. Physico-chemical stability and in vitro digestibility of beta-caroteneloaded lipid nanoparticles of cupuacu butter (Theobroma grandiflorum) produced by the phase inversion temperature (PIT) method. J. Food Eng. 192: 93–102 (2017)CrossRefGoogle Scholar
- Mao L, Xu D, Yang J, Yuan F, Gao Y, and Zhao, J. Effects of small and large molecule emulsifiers on the characteristics of β-carotene nanoemulsions prepared by high pressure homogenization. Food Technol. Biotechnol. 47: 336–342 (2009)Google Scholar