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The ameliorative effect of Protaetia brevitarsis Larvae in HFD-induced obese mice

  • Eun-Mi Ahn
  • Noh-Yil Myung
  • Hyeon-A Jung
  • Su-Jin KimEmail author
Article
  • 29 Downloads

Abstract

Protaetia brevitarsis Lewis (P. brevitarsis) larvae, edible insect, traditionally is consumed for various health benefits. However, little information is available with respect to its direct anti-obesity effects. Thus, the present study was designed to investigate the regulatory effect of P. brevitarsis against high-fat diet (HFD)-induced obese mice. HFD-fed mice showed an increase in the body weight and serum levels of total cholesterol as well as low-density lipoprotein-cholesterol, and triglycerides. The administration of P. brevitarsis to obese mice induced a reduction in their body weight, lipid accumulation in liver and serum lipid parameter compared with the HFD fed mice. P. brevitarsis also inhibited the expression of obesity-related genes such as CCAAT/enhancer-binding protein alpha and fatty acid synthesis in 3T3-L1 cells. Moreover, oleic acid was identified as predominant fatty acid of P. brevitarsis by gas chromatography analysis. Conclusively, these findings suggested that P. brevitarsis may help to prevent obesity and obesity-related metabolic diseases.

Keywords

Protaetia brevitarsis Lewis Edible insect Obesity High-fat diet Oleic acid 

Notes

Acknowledgements

This work was supported by “Food Functionality Evaluation program” under the Ministry of Agriculture, Food and Rural Affairs and partly Korea Food Research Institute.

Compliance with ethical standards

Conflict of interest

The authors declare that there are no conflict of interest.

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Copyright information

© The Korean Society of Food Science and Technology 2019

Authors and Affiliations

  • Eun-Mi Ahn
    • 1
  • Noh-Yil Myung
    • 2
  • Hyeon-A Jung
    • 3
  • Su-Jin Kim
    • 1
    Email author
  1. 1.Department of Biotechnology and ConvergenceDaeguHanny UniversityGyeongsanRepublic of Korea
  2. 2.Department of Oriental Medicine and HealthcareWonkwang Digital UniversityIksanRepublic of Korea
  3. 3.Department of Herbal Cuisine and NutritionDaeguHanny UniversityGyeongsanRepublic of Korea

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