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Hernia

pp 1–17 | Cite as

Open darn repair vs open mesh repair of inguinal hernia: a systematic review and meta-analysis of randomised and non-randomised studies

  • D. A. FinchEmail author
  • V. A. Misra
  • S. Hajibandeh
Review

Abstract

Objectives

To compare the outcomes of open darn repair vs open mesh repair in patients undergoing inguinal hernia repair.

Methods

We performed a systematic review and conducted a search of electronic information sources to identify all observational studies and randomised controlled trials (RCTs) investigating outcomes of open darn repair vs open mesh repair for inguinal hernias. Hernia recurrence was considered as the primary outcome measure. The secondary outcome measures included surgical site infection (SSI), haematoma, seroma, neuralgia, urinary retention, length of hospital stay, time to return to normal activities or work, testicular atrophy, operative time and chronic pain. Random or fixed effects modelling was applied to calculate pooled outcome data.

Results

Six RCTs, enrolling 1480 patients with 1485 hernias, and 4 observational studies, enrolling 1564 patients with 1641 hernias, were included. Meta-analysis of RCTs showed no significant difference in terms of recurrence (RD 0.00, 95% CI − 0.01 to 0.01, P = 0.86), SSI (OR 0.83, 95% CI 0.46–1.49, P = 0.52), haematoma (OR 1.21, 95% CI 0.62–2.38, P = 0.57), seroma (OR 0.83, 95% CI 0.42–1.65, P = 0.60), neuralgia (OR 1.05, 95% CI 0.29–3.73, P = 0.94), urinary retention (OR 1.44, 95% CI 0.64–3.21, P = 0.38), length of hospital stay (MD 0.09, 95% CI − 0.28 to 0.46, P = 0.63), time to return to normal activities or work (MD 0.88, 95% CI − 0.90 to 2.66, P = 0.33), testicular atrophy (RD 0.00, 95% CI − 0.02 to 0.02, P = 1.00), and operative time (MD 2.69, 95% CI − 1.75 to 7.14, P = 0.62) between the darn repair and mesh repair groups. Meta-analysis of observational studies also showed no significant difference in terms of recurrence (RD 0.00, 95% CI − 0.02 to 0.02, P = 0.99), SSI (OR 0.47, 95% CI 0.14–1.62, P = 0.23), haematoma (OR 1.07, 95% CI 0.45–2.55, P = 0.89), seroma (OR 0.12, 95% CI 0.01–2.27, P = 0.16), neuralgia (OR 0.25, 95% CI 0.05–1.21, P = 0.08), urinary retention (OR 1.53, 95% CI 0.20–11.96, P = 0.69), time to return to normal activities or work (MD 2.13, 95% CI − 2.18 to 6.44, P = 0.33), testicular atrophy (RD − 0.01, 95% CI − 0.02 to 0.01, P = 0.49), and operative time (MD − 4.76, 95% CI − 13.23 to 3.71, P = 0.27) between the two groups. The evidence was inconclusive for chronic pain. The quality of available evidence was moderate.

Conclusions

Our results suggest that open darn repair is comparable with open mesh repair for inguinal hernias. Considering that consequences of mesh complications in inguinal hernia repair, albeit rare, can be significant, open darn repair provides an equally credible alternative to open mesh repair for inguinal hernias. Further studies are required to investigate patient-reported outcomes and to elicit a superior non-mesh technique.

Keywords

Inguinal hernia Darn repair Mesh repair 

Notes

Author contributions

Conception and design: SH. Data collection: DAF, VAM, and SH. Analysis and interpretation: DAF and SH. Writing the article: DAF and SH. Critical revision of the article: DAF and SH. Final approval of the article: DAF, VAM and SH. Statistical analysis: SH.

Funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Compliance with ethical standards

Conflict of interest

DAF declares no conflict of interest. VAM declares no conflict of interest. SH declares no conflict of interest.

Ethical approval

Considering the nature of this study, ethical approval was not required.

Human and animal rights

This study is a systematic review with meta-analysis of outcomes which does not include research directly involving human or animal participation.

Informed consent

Considering the nature of this study, informed consent was not required.

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Copyright information

© Springer-Verlag France SAS, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of General SurgeryPinderfields General HospitalWakefieldUK
  2. 2.Department of General SurgeryRoyal Bolton HospitalBoltonUK
  3. 3.Department of General SurgeryNorth Manchester General HospitalManchesterUK

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