One-pot synthesis of copper nanoparticles on glass: applications for non-enzymatic glucose detection and catalytic reduction of 4-nitrophenol
Thin film of metallic Cu nanoparticles was synthesized by a one-pot chemical reduction method at ambient temperature. Cu(II) acetate monohydrate and hydrazine monohydrate were used as precursor and reducing agent without additional surfactants to form uniform layer of Cu nanoparticle layer on a glass substrate (Cu/G). The XRD and the effectiveness of the electrocatalytic and catalytic properties of the Cu/G have been applied for an amperometric detection of glucose and for the chemical reduction of 4-nitrophenol. The former exhibited the detection limit as low as 2.47 μM with a linear range of 0.01–0.2 mM, while the latter showed the efficient catalytic activity with a high rate constant of 0.503/min. The current method suggested in this work might be useful for the fabrication of glass-based Cu nanoparticles electrodes for industrial and biomedical applications.
KeywordsCopper nanoparticles Electrochemical sensor Hydrogenation reaction Glucose 4-Nitrophenol
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (NRF-2015M1A2A2054996, NRF-2016R1A2B2012061). It was also supported by the Technology Development Program to Solve Climate Changes of the National Research Foundation (NRF), funded by the Ministry of Science, ICT & Future Planning (NRF-2016M1A2A2940912). This work was also supported by the Dongguk University Research Fund of 2016.
- 2.Dong C, Cai H, Zhang X, Cao C (2014) Synthesis and characterization of monodisperse copper nanoparticles using gum acacia. Physica E 57:12–20Google Scholar
- 9.Mei L-P, Song P, Feng J-J, Shen JH, Wang W, Wang AJ, Weng X (2015) Nonenzymatic amperometric sensing of glucose using a glassy carbon electrode modified with a nanocomposite consisting of reduced graphene oxide decorated with Cu2O nanoclusters. Microchim Acta 182(9-10):1701–1708CrossRefGoogle Scholar