Journal of Solid State Electrochemistry

, Volume 23, Issue 1, pp 187–194 | Cite as

A rapid and sensitive electrochemical sensor for hydroxyl free radicals based on self-assembled monolayers of carboxyl functionalized graphene

  • Yancai LiEmail author
  • Yuhui Li
  • Yingzhen Zhang
  • Yingying Song
  • Yingying Jiang
Original Paper


In this work, carboxyl-functionalized graphene (CFG) was immobilized on glassy carbon electrode (GCE) by self-assembled monolayers (SAMs) based on covalent interaction with ethylenediamine as an arm linker. The obtained (CFG-NHCH2CH2NH)/GCE can be used as rapid and sensitive electrochemical sensor for hydroxyl free radicals (•OH). In the process of determination, the concentration of •OH was acquired not directly but through the only captured product 3,4-dihydroxybenzoic acid (3,4-DHBA), which is adopting 4-hydroxybenzoic acid (4-HBA) as the •OH trap. The glassy carbon electrode modified with carboxyl-functionalized graphene exhibits well conductivity and electron transfer ability, and also displays good electrocatalytic activity towards the electrochemical redox of 3,4-DHBA. The proposed sensor displays a good linear range from 1.0 to 450.0 μM for 3,4-DHBA with a low detection limit of 0.17 μM (S/N = 3). More importantly, the sensing platform can be successfully applied for •OH detection with the 4-HBA as the •OH trap.


Carboxyl-functionalized graphene Self-assembled monolayers Hydroxyl free radicals 3,4-dihydroxybenzoic acid 4-hydroxybenzoic acid Electrochemical sensor 


Funding information

This work was supported by the National Natural Science Foundation of China (No. 21175115); the Natural Science Foundation of Fujian province in China (2016J01067); and the Innovation Base Foundation for Graduate Students Education of Fujian Province.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Yancai Li
    • 1
    • 2
    Email author
  • Yuhui Li
    • 1
  • Yingzhen Zhang
    • 1
  • Yingying Song
    • 1
  • Yingying Jiang
    • 1
  1. 1.College of Chemistry, Chemical Engineering and EnvironmentMinnan Normal UniversityZhangzhouPeople’s Republic of China
  2. 2.Fujian Province Key Laboratory of Modern Analytical Science and Separation TechnologyMinnan Normal UniversityZhangzhouPeople’s Republic of China

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