Decorating Mn3O4 nanoparticle on NiO nanoflake arrays for high-performance electrochemical biosensors
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Substrate materials play a significant role in the improvement of electrochemical biosensors. In the present work, NiO nanoflake arrays were fully and uniformly decorated with Mn3O4 nanoparticles by stepwise method. The as-prepared samples were characterized by scanning electron microscopy (SEM), x-ray diffractionmeter (XRD), transmission electron microscopy (TEM), x-ray photoelectron spectroscopy (XPS), energy-dispersive x-ray spectroscopy (EDS), and chronoamperometry. Subsequently, the optimized Mn3O4 nanoparticle/NiO nanoflake arrays were employed as substrate to fabricate electrochemical biosensors for glucose determination. The results demonstrated that as-prepared glucose biosensors could achieve 226.2 μA mM−1 cm−2 of sensitivity and 1.0 μM of detection limit, respectively. In addition, the linear range was between 9.9 and 3665.0 μM. The developed substrate could also be extended to construct electrochemical biosensors based on other oxidase with excellent performance.
KeywordsNiO Mn3O4 Synergistic effect Biosensing Glucose
The authors appreciate the financial supports from National Natural Science Foundation of China (Nos. 51402081, 51502071, and 31501576) and Fundamental Research Funds for the Central Universities (No. JZ2017HGTB0203). The authors also would like to thank the financial support from the 111 Project (B18018).
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