Journal of Solid State Electrochemistry

, Volume 23, Issue 1, pp 135–142 | Cite as

Decorating Mn3O4 nanoparticle on NiO nanoflake arrays for high-performance electrochemical biosensors

  • Yao Wang
  • Jiewu CuiEmail author
  • Yan Wang
  • Dongbo Yu
  • Sheng ChengEmail author
  • Hongmei Zheng
  • Xia Shu
  • Yong Zhang
  • Yucheng WuEmail author
Original Paper


Substrate materials play a significant role in the improvement of electrochemical biosensors. In the present work, NiO nanoflake arrays were fully and uniformly decorated with Mn3O4 nanoparticles by stepwise method. The as-prepared samples were characterized by scanning electron microscopy (SEM), x-ray diffractionmeter (XRD), transmission electron microscopy (TEM), x-ray photoelectron spectroscopy (XPS), energy-dispersive x-ray spectroscopy (EDS), and chronoamperometry. Subsequently, the optimized Mn3O4 nanoparticle/NiO nanoflake arrays were employed as substrate to fabricate electrochemical biosensors for glucose determination. The results demonstrated that as-prepared glucose biosensors could achieve 226.2 μA mM−1 cm−2 of sensitivity and 1.0 μM of detection limit, respectively. In addition, the linear range was between 9.9 and 3665.0 μM. The developed substrate could also be extended to construct electrochemical biosensors based on other oxidase with excellent performance.


NiO Mn3O4 Synergistic effect Biosensing Glucose 



The authors appreciate the financial supports from National Natural Science Foundation of China (Nos. 51402081, 51502071, and 31501576) and Fundamental Research Funds for the Central Universities (No. JZ2017HGTB0203). The authors also would like to thank the financial support from the 111 Project (B18018).

Supplementary material

10008_2018_4117_MOESM1_ESM.docx (6 mb)
ESM 1 (DOCX 6111 kb)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.School of Materials Science and EngineeringHefei University of TechnologyHefeiPeople’s Republic of China
  2. 2.Key Laboratory of Advanced Functional Materials and Device of Anhui ProvinceHefeiPeople’s Republic of China

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