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Incidence of diagnosed pediatric anxiety disorders and use of prescription drugs: a nation-wide registry study

  • Helga AskEmail author
  • Marte Handal
  • Lars Johan Hauge
  • Ted Reichborn-Kjennerud
  • Svetlana Skurtveit
Original Contribution
  • 70 Downloads

Abstract

The aim of this study was to calculate time trends in incidence of diagnosed anxiety disorders, including obsessive–compulsive disorder, and post-traumatic stress disorder, and to examine changes in use of prescribed drugs in the Norwegian pediatric population. Furthermore, we aimed to investigate whether comorbid mental disorders are associated with the use of prescribed drugs. Nation-wide registries with data from 2008 to 2015 were used, covering diagnostic data from primary health care [the Norwegian database for the control and reimbursement of health expenses (KUHR)] and secondary health care [the Norwegian Patient registry (NPR)], and data on prescribed drugs [the Norwegian prescription database, (NorPD)]. Data from the two latter were linked. During the period 2010–2015, 19,154 children and adolescents (61% girls) received a first diagnosis of anxiety disorders in primary care. The corresponding number from secondary care was 17,115 (61% girls). The incidence of diagnosed anxiety disorders increased over time, especially in girls, with an overall raise of ~ 2 per 1000 children across 2010–2015. Anti-anxiety drugs were used by < 12% of diagnosed children and < 25% of diagnosed adolescents, mainly by those with several contacts with the specialist health care system. There was no strong indications of an increase over time. Of other drugs, the most frequently prescribed were hypnotics and psychostimulants. Psychiatric comorbidity (33–55%) contributed to the use of drugs, including anti-anxiety drugs. The incidence of diagnosed anxiety disorders increased from 2010 to 2015, but the percentage using anti-anxiety drugs was stable. Drug use appears to be in line with the Norwegian guidelines.

Keywords

Anxiety disorders Prescription drugs Post-traumatic stress disorder Obsessive–compulsive disorder Comorbidity 

Notes

Acknowledgements

Data from the Norwegian Patient Register have been used in this publication. The interpretation and reporting of these data are the sole responsibility of the authors, and no endorsement by the Norwegian Patient Register is intended nor should be inferred. The authors are grateful to Vidar Hjellvik for preparing the registry data. The study was approved by The Regional Committee for Medical Research Ethics (2010/131) and by the Norwegian Data Protection Authority (10/00447-5).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no potential conflicts of interest.

Supplementary material

787_2019_1419_MOESM1_ESM.docx (538 kb)
Supplementary file1 (DOCX 537 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Norwegian Institute of Public HealthOsloNorway
  2. 2.Institute of Clinical MedicineUniversity of OsloOsloNorway
  3. 3.Norwegian Centre for Addiction ResearchUniversity of OsloOsloNorway

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