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Laser therapy for recurrent aphthous stomatitis: an overview

  • Juliana Amorim dos Santos
  • Ana Gabriela Costa Normando
  • Isabela Porto de Toledo
  • Gilberto Melo
  • Graziela De Luca Canto
  • Alan Roger Santos-Silva
  • Eliete Neves Silva GuerraEmail author
Review
  • 59 Downloads

Abstract

Objectives

To evaluate therapeutic effects of laser therapy on patients with recurrent aphthous stomatitis assessing evidences from previously published systematic reviews.

Materials and methods

An overview of systematic reviews was conducted based on PRISMA checklist. Search strategies were developed and adapted for six different electronic databases and a gray literature search was also performed. The methodology quality of the included systematic reviews was assessed by the Measurement Tool to Assess the Methodological Quality of Systematic Reviews 2 (AMSTAR 2).

Results

After a two-step selection, five systematic reviews were included. Methodology quality was considered as a high risk of bias in two systematic reviews, while in the other three were graded as moderate. The systematic reviews’ conclusions demonstrated that all included systematics reviews showed positive effects of laser therapy for pain relief, and most of them demonstrated healing improvement. A meta-analysis was not feasible due to heterogeneity in treatments parameters.

Conclusions

Evidence suggested that laser therapy is an effective tool to treat recurrent aphthous stomatitis; nevertheless, more randomized clinical trials should be conducted to compare different lasers parameters.

Clinical relevance

The present overview evaluated recent evidence about laser therapy for recurrent aphthous stomatitis management in order to contribute for evidence-based dentistry and decision-making. This overview suggests that laser therapy is a safe and promising alternative to treat recurrent aphthous stomatitis, since it promotes wound healing and pain relief.

Keywords

Lasers Oral ulcer Oral medicine Systematic review Evidence-based medicine Overview 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study, formal consent is not required.

Supplementary material

784_2019_3144_MOESM1_ESM.docx (42 kb)
ESM 1 (DOCX 42 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Juliana Amorim dos Santos
    • 1
  • Ana Gabriela Costa Normando
    • 1
  • Isabela Porto de Toledo
    • 1
    • 2
  • Gilberto Melo
    • 2
  • Graziela De Luca Canto
    • 2
  • Alan Roger Santos-Silva
    • 3
  • Eliete Neves Silva Guerra
    • 1
    Email author
  1. 1.Laboratory of Oral Histopathology, Health Sciences FacultyUniversity of BrasiliaBrasiliaBrazil
  2. 2.Brazilian Centre for Evidence-Based Research, Department of DentistryFederal University of Santa CatarinaFlorianópolisBrazil
  3. 3.Oral Diagnosis, Piracicaba Dental SchoolUniversity of Campinas (UNICAMP)São PauloBrazil

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