Coexistence of oral lichen planus and pemphigus vulgaris
Letter to the Editor
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Over the past decades, several cases regarding the coexistence of two mucosal/skin-related autoimmune/inflammatory conditions have been reported. One of the least reported is the coexistence of pemphigus vulgaris (PV) and lichen planus (LP). Regardless of a few reports of coexistence of oral LP (OLP) or generalized LP with PV, which had been published more than two decades ago, none has been reported in the recent years [ 1, 2]. As a brief survey in registered cases of PV in Razi Hospital, Tehran University of Medical Sciences, we have focused on two patients affected with this coexistence. Both patients had a clinical and histopathological diagnosis of PV. Additionally, they had positive intercellular direct immunofluorescence and detectable autoantibodies against the desmoglein (Dsg)1 and/or Dsg3 at the beginning of their disease. Years after diagnosis of PV, OLP has been manifested in these patients. In contrast to their PV, which responded to conventional treatments,...
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Conflict of interest
The authors declare that they have no conflict of interest.
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