Clinical Oral Investigations

, Volume 22, Issue 8, pp 2953–2955 | Cite as

Coexistence of oral lichen planus and pemphigus vulgaris

  • Kamran Balighi
  • HamidReza Mahmoudi
  • Soheil Tavakolpour
  • Maryam DaneshpazhoohEmail author
Letter to the Editor

Dear Editor,

Over the past decades, several cases regarding the coexistence of two mucosal/skin-related autoimmune/inflammatory conditions have been reported. One of the least reported is the coexistence of pemphigus vulgaris (PV) and lichen planus (LP). Regardless of a few reports of coexistence of oral LP (OLP) or generalized LP with PV, which had been published more than two decades ago, none has been reported in the recent years [ 1, 2]. As a brief survey in registered cases of PV in Razi Hospital, Tehran University of Medical Sciences, we have focused on two patients affected with this coexistence. Both patients had a clinical and histopathological diagnosis of PV. Additionally, they had positive intercellular direct immunofluorescence and detectable autoantibodies against the desmoglein (Dsg)1 and/or Dsg3 at the beginning of their disease. Years after diagnosis of PV, OLP has been manifested in these patients. In contrast to their PV, which responded to conventional treatments,...


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Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Kamran Balighi
    • 1
  • HamidReza Mahmoudi
    • 1
  • Soheil Tavakolpour
    • 1
  • Maryam Daneshpazhooh
    • 1
    Email author
  1. 1.Autoimmune Bullous Diseases Research Center, Razi HospitalTehran University of Medical SciencesTehranIran

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