Systematic and meta-analytic analysis of cross-sectional and longitudinal explorations of bone health in youth with obesity: from methodological considerations to clinical relevance
Our team has recently performed a systematic and meta-analytic analyses of the literature related to the effects of multidisciplinary weight loss interventions on bone health in children and adolescents with obesity . In a recent issue of the Journal of Bone and Mineral Metabolism, Alwardat and Alwardat commented on our work, nicely pointing the scientific and clinical interest of our review while stressing several methodological limitations .
We understand the points raised by Alwardat and Alwardat through their all commentary, highlighting some important methodological aspects of meta-analysis and systematic reviews’ processes that must be respected by authors to ensure the validity of such analyses and the strength of their conclusions. Although we want to thank the authors for their interest, we believe that their comments do not contribute to the scientific area, being moreover not adapted in most cases.
First, the author seems to suggest that we did employ a non-systematic...
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