Depression during perimenopause: the role of the obstetrician-gynecologist

  • Greta B. Raglan
  • Jay Schulkin
  • Elizabeth MicksEmail author
Review Article


Depression in women is more common during perimenopause (the transition to menopause) than at other times in the life cycle. Symptoms of depression may be different in perimenopausal women compared to younger or older women, and are often dismissed as part of normal menopause. This is an expert narrative review. There are several evidence-based screening modalities which can be integrated into routine women’s health visits, and can facilitate distinguishing between depression and normal perimenopausal symptoms. There is emerging evidence regarding the effect of hormonal changes on the development of perimenopausal depression and its optimal treatment, though critical research gaps remain. Obstetrician-gynecologists and other primary care providers play a vital role in the detection and management of depression in women. Providers caring for women during perimenopause have a unique opportunity to diagnose depression in their patients and identify appropriate treatment options.


Perimenopause Depression Menopause Mental health Screening 


Author contributions

G Raglan: manuscript writing/editing

J Schulkin: protocol/project development

E Micks: manuscript writing/editing

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of PsychiatryUniversity of MichiganAnn ArborUSA
  2. 2.Department of Obstetrics and GynecologyUniversity of Washington School of MedicineSeattleUSA

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