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Amino Acids

pp 1–13 | Cite as

Composition of polyamines and amino acids in plant-source foods for human consumption

  • Yongqing Hou
  • Wenliang He
  • Shengdi Hu
  • Guoyao WuEmail author
Original Article

Abstract

Dietary polyamines and amino acids (AAs) are crucial for human growth, development, reproduction, and health. However, the scientific literature shows large variations in polyamine and AA concentrations among major staple foods of plant origin, and there is a scarcity of information regarding their complete composition of AAs. To provide a much-needed database, we quantified polyamines, agmatine, and AAs in select plant-source foods. On the dry matter basis, total polyamines were most abundant in corn grains, followed by soybeans, sweet potatoes, pistachio nuts, potatoes, peanuts, wheat flour and white rice in descending order. Glutamine was the most abundant AA in pistachio nuts, wheat flour and white rice, arginine in peanuts, leucine in corn grains, glutamate in soybeans, and asparagine in potatoes and sweet potatoes. Glutamine was the second most abundant AA in corn grains, peanuts, potatoes, and soybeans, arginine in pistachio nuts, proline in wheat flour, and glutamate in sweet potatoes and white rice. Free AAs represented ≤ 3.1% of total AAs in corn grains, peanuts, pistachio nuts, soybeans, wheat flour and white rice, but 34.4% and 28.5% in potatoes and sweet potatoes, respectively. Asparagine accounted for 32.3%, 17.5%, and 19.4% of total free AAs in potatoes, sweet potatoes, and white rice, respectively. The content of histidine, glycine, lysine, tryptophan, methionine, cysteine, and threonine was relatively low in corn grains, potatoes, sweet potatoes, and white rice. All of the analyzed plant-source foods lacked taurine, creatine, carnosine and anserine (antioxidants that are abundant in meats and also present in milk), and contained little 4-hydroxyproline. Proper proportions of plant- and animal-source products are likely most desirable for optimizing human nutrition and health.

Keywords

Plant-source foods Polyamines Amino acids Arginine Methionine Humans 

Abbreviations

AAs

Amino acids

BCAAs

Branched-chain amino acids

DM

Dry matter

HPLC

High-performance liquid chromatography

Notes

Acknowledgements

This work was supported, in part, by the Hubei Hundred Talent Program, Hubei Provincial Foundation of Natural Science (2016CFA070), the Program of National Agricultural Research Outstanding Talents of China (2015), the U.S. Beef Checkoff through the National Cattlemen’s Beef Association (NCBA), and Texas A&M AgriLife Research (H-8200). We thank Dr. Gayan I. Nawaratna for technical assistance in the study.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethics statement

This study involved plant-source foods. No approval of animal use protocols is required.

Informed consent

No informed consent is required for this study.

Supplementary material

726_2019_2751_MOESM1_ESM.doc (75 kb)
Supplementary material 1 (DOC 75 kb)

References

  1. Abiose SH, Ikujenlola AV (2014) Comparison of chemical composition, functional properties and amino acids composition of quality protein maize and common maize (Zea mays L). Afr J Food Sci Technol 5:81–89Google Scholar
  2. Agostinelli E (2016) Polyamines and transglutaminases: future perspectives. Amino Acids 48:2273–2281CrossRefGoogle Scholar
  3. Agostinelli E, Marques MP, Calheiros R, Gil FP, Tempera G, Viceconte N, Battaglia V, Grancara S, Toninello A (2010) Polyamines: fundamental characters in chemistry and biology. Amino Acids 38:393–403CrossRefGoogle Scholar
  4. Assaad H, Zhou L, Carroll RJ, Wu G (2014) Rapid publication-ready MS-Word tables for one-way ANOVA. SpringerPlus 3:474CrossRefGoogle Scholar
  5. Badenhop AF, Hackler LR (1971) Protein quality of dry roasted soybeans: amino acid composition and protein efficiency ratio. J Food Sci 36:1–4CrossRefGoogle Scholar
  6. Bardócz S, Grant G, Brown DS, Ralph A, Pusztai A (1993) Polyamines in food—implications for growth and health. J Nutr Biochem 4:66–71CrossRefGoogle Scholar
  7. Bardócz S, Duguid TJ, Brown DS, Grant G, Pusztai A, White A, Ralph A (1995) The importance of dietary polyamines in cell regeneration and growth. Br J Nutr 73:819–828CrossRefGoogle Scholar
  8. Bártová V, Bárta J, Brabcová A, Zdráhal Z, Horackova V (2015) Amino acid composition and nutritional value of four cultivated South American potato species. J Food Compos Anal 40:78–85CrossRefGoogle Scholar
  9. Blachier F, Mariotti F, Huneau JF, Tomé D (2007) Effects of amino acid-derived luminal metabolites on the colonic epithelium and physiopathological consequences. Amino Acids 33:547–562CrossRefGoogle Scholar
  10. Blachier F, Davila AM, Benamouzig R, Tome D (2011) Channelling of arginine in NO and polyamine pathways in colonocytes and consequences. Front Biosci (Landmark Ed) 16:1331–1343CrossRefGoogle Scholar
  11. Bazer FW, Burghardt RC, Johnson GA, Spencer TE, Wu G (2018) Mechanisms for the establishment and maintenance of pregnancy: synergies from scientific collaborations. Biol Reprod 99:225–241CrossRefGoogle Scholar
  12. Chung KH, Shin KO, Hwang HJ, Choi KS (2013) Chemical composition of nuts and seeds sold in Korea. Nutr Res Pract 7:82–88CrossRefGoogle Scholar
  13. Clarke JA, Brar GS, Procopiou J (1976) Fatty acid, carbohydrate and amino acid composition of pistachio (Pistacia vera) kernels. Qual Plant 25:219–225CrossRefGoogle Scholar
  14. Dai ZL, Wu ZL, Jia SC, Wu G (2014a) Analysis of amino acid composition in proteins of animal tissues and foods as pre-column o-phthaldialdehyde derivatives by HPLC with fluorescence detection. J Chromatogr B 964:116–127CrossRefGoogle Scholar
  15. Dai ZL, Wu ZL, Wang JJ, Wang XQ, Jia SC, Bazer FW, Wu G (2014b) Analysis of polyamines in biological samples by HPLC involving pre-column derivatization with o-phthalaldehyde and N-acetyl-l-cysteine. Amino Acids 46:1557–1564CrossRefGoogle Scholar
  16. Dai ZL, Wu ZL, Hang SQ, Zhu WY, Wu G (2015) Amino acid metabolism in intestinal bacteria and its potential implications for mammalian reproduction. Mol Hum Reprod 21:389–409CrossRefGoogle Scholar
  17. Ducci M, Pacchini S, Niccolini A, Gazzano A, Cerri D, Gadea J, Bobowiec R, Sighieri C, Martelli F (2006) Concentrations of carnosine, anserine, L-histidine and 3-methyl histidine in boar spermatozoa and sheep milk by a modified HPLC method. Pol J Vet Sci 9:159–163Google Scholar
  18. Eisenberg T, Knauer H, Schauer A et al (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11:1305–1314CrossRefGoogle Scholar
  19. Ewart JAD (1967) Amino acid analyses of cereal flour proteins. J Sci Food Agric 18:548–552CrossRefGoogle Scholar
  20. Fan X, Li S, Wu ZL, Dai ZL, Li J, Wang XL, Wu G (2019) Glycine supplementation to breast-fed piglets attenuates postweaning jejunal epithelial apoptosis: a functional role of CHOP signaling. Amino Acids 51:463–473CrossRefGoogle Scholar
  21. FAO (2017) FAOSTAT—Food and Agriculture Organization of the United Nations. http://www.fao.org/faostat/en/#data/FBS. Accessed 6 March 2019
  22. FAO/WHO/UNU (2007) Technical Report Series 935: protein and amino acid requirements in human nutrition. WHO Press, Geneva, pp 1–265Google Scholar
  23. Farriol M, Venereo Y, Orta X, Company C, Gomez P, Delgado G et al (2004) Ingestion of antioxidants and polyamines in patients with severe burns [in Spanish]. Nutr Hosp 19:300–304Google Scholar
  24. Fu WJ, Stromberg AJ, Viele K et al (2010) Statistics and bioinformatics in nutritional sciences: analysis of complex data in the era of systems biology. J Nutr Biochem 21:561–572CrossRefGoogle Scholar
  25. Goldflus F, Ceccantini M, Santos W (2006) Amino acid content of soybean samples collected in different Brazilian states – Harvest 2003/2004. Braz J Poultry Sci 8:105–111CrossRefGoogle Scholar
  26. Han J, Liu K (2010) Changes in composition and amino acid profile during dry grind ethanol processing from corn and estimation of yeast contribution toward DDGS proteins. J Agric Food Chem 58:3430–3437CrossRefGoogle Scholar
  27. Haynes TE, Li P, Li XL et al (2009) l-Glutamine or l-alanyl-l-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes. Amino Acids 37:131–142CrossRefGoogle Scholar
  28. Hou YQ, Wu G (2017) Nutritionally nonessential amino acids: A misnomer in nutritional sciences. Adv Nutr 8:137–139CrossRefGoogle Scholar
  29. Hou YQ, Wu G (2018) Nutritionally essential amino acids. Adv Nutr 9:849–851Google Scholar
  30. Hou YQ, Yin YL, Wu G (2015) Dietary essentiality of "nutritionally nonessential amino acids" for animals and humans. Exp Biol Med 240:997–1007CrossRefGoogle Scholar
  31. Hughes BP (1957) The amino -acid composition of potato protein and of cooked potato. Br J Nutr 12:188–195CrossRefGoogle Scholar
  32. Hunter DC, Burritt DJ (2012) Polyamines of plant origin—an important dietary consideration for human health. In: Rao V (ed) Phytochemicals as nutraceuticals—global approaches to their role in nutrition and health. InTech, Rijeka, pp 225–244Google Scholar
  33. Institute of Medicine (IOM) (2005) Dietary reference intakes for energy, carbohydrates, fiber, fat, fatty acids, cholesterol, proteins, and amino acids. The National Academies Press, Washington, DCGoogle Scholar
  34. Ji Y, Dai ZL, Sun SQ, Ma XS, Yang Y, Tso P, Wu G, Wu ZL (2018) Hydroxyproline attenuates dextran sulfate sodium-induced colitis in mice: involvement of the NF-κB signaling and oxidative stress. Mol Nutr Food Res 62:1800494CrossRefGoogle Scholar
  35. Jobgen WS, Fried SK, Fu WJ, Meininger CJ, Wu G (2006) Regulatory role for the arginine–nitric oxide pathway in metabolism of energy substrates. J Nutr Biochem 17:571–588CrossRefGoogle Scholar
  36. Kahana C (2009) Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor. Essays Biochem 46:47–61CrossRefGoogle Scholar
  37. Kai M, Miyazaki T, Yamaguchi M, Ohkura Y (1983) High performance liquid chromatography of guanidino compounds using benzoin as pre-column derivatization reagent. J Chromatogr 268:417–424CrossRefGoogle Scholar
  38. Kalač P (2014) Health effects and occurrence of dietary polyamines: a review for the period 2005–mid 2013. Food Chem 161:27–39CrossRefGoogle Scholar
  39. Kalač P, Krizek M, Pelikánová T, Langová M, Veškrna O (2005) Contents of polyamines in selected foods. Food Chem 90:561–564CrossRefGoogle Scholar
  40. Kaldy MS, Markakis P (1972) Amino acid composition of selected potato varieties. J Food Sci 37:375–377CrossRefGoogle Scholar
  41. Keeney DR (1970) Protein and amino acid composition of maize grain as influenced by variety and fertility. J Sci Food Agric 21:182–184CrossRefGoogle Scholar
  42. Khoi BH, Dien LD, Lásztity R, Salgó A (1987) The protein and the amino acid composition of some rice and maize varieties grown in North Vietnam. J Sci Food Agric 39:137–143CrossRefGoogle Scholar
  43. Kong XF, Wang XQ, Yin YL, Li XL, Gao HJ, Bazer FW, Wu G (2014) Putrescine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. Biol Reprod 91:106CrossRefGoogle Scholar
  44. Kusano T, Berberich T, Tateda C, Takahashi Y (2008) Polyamines: essential factors for growth and survival. Planta 228:367–381CrossRefGoogle Scholar
  45. Larqué E, Sabater-Molina A, Zamora S (2007) Biological significance of dietary polyamines. Nutrition 23:87–95CrossRefGoogle Scholar
  46. Lefèvre PL, Palin MF, Murphy BD (2011) Polyamines on the reproductive landscape. Endocr Rev 32:694–712CrossRefGoogle Scholar
  47. Lenis YY, Elmetwally MA, Tang WJ, Satterfield C, Dunlap K, Wu G, Bazer FW (2018) Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep. Amino Acids 50:293–308CrossRefGoogle Scholar
  48. Li P, Wu G (2018) Roles of dietary glycine, proline and hydroxyproline in collagen synthesis and animal growth. Amino Acids 50:29–38CrossRefGoogle Scholar
  49. Li XL, Rezaei R, Li P, Wu G (2011) Composition of amino acids in feed ingredients for animal diets. Amino Acids 40:1159–1168CrossRefGoogle Scholar
  50. McDermott EE, Pace J (1957) The content of amino-acids in white flour and bread. Br J Nutr 11:446–452CrossRefGoogle Scholar
  51. Mossé J, Huet JC, Baudet J (1988) The amino acid composition of rice grain as a function of nitrogen content as compared with other cereals: a reappraisal of rice chemical scores. J Cereal Sci 8:165–175CrossRefGoogle Scholar
  52. Nishibori N, Fujihara S, Akatuki T (2007) Amounts of polyamines in foods in Japan and intake by Japanese. Food Chem 100:491–497CrossRefGoogle Scholar
  53. Nishimura K, Shiina R, Kashiwagi K, Igarashi K (2006) Decrease in polyamines with aging and their ingestion from food and drink. J Biochem 139:81–90CrossRefGoogle Scholar
  54. Okamoto A, Sugi E, Koizumi Y, Yanagida F, Udaka S (1997) Polyamine content of ordinary foodstuffs and various fermented foods. Biosci Biotechnol Biochem 61:1582–1584CrossRefGoogle Scholar
  55. Ooman HAPC, Spoon W, Heesterman JE, Reinard J, Luyken R, Slum P (1961) The sweet potato as the staff of life of the highland Papuan. Trop Geogr Med 13:55–66Google Scholar
  56. Patrick RM, Hoskins FH, Wilson E, Peterson FJ (1974) Protein and amino acid content of rice as affected by application of nitrogen fertilizer. Cereal Chem 51:84–95Google Scholar
  57. Pegg AE, Casero RA Jr (2011) Current status of the polyamine research field. Methods Mol Biol 720:3–35CrossRefGoogle Scholar
  58. Perez-Leal O, Merali S (2012) Regulation of polyamine metabolism by translational control. Amino Acids 42:611–617CrossRefGoogle Scholar
  59. Purcell AE, Walter WM Jr (1982) Stability of amino acids during cooking and processing of sweet potatoes. J Agric Food Chem 30:443–444CrossRefGoogle Scholar
  60. Ralph A, Englyst K, Bardócz S (1999) Polyamine content of the human diet. In: Bardócz S, White A (eds) Polyamines in health and nutrition. Kluwer, Massachusetts, pp 123–137Google Scholar
  61. Rizzo G, Baroni L (2018) Soy, soy foods and their role in vegetarian diets. Nutrients 10:43CrossRefGoogle Scholar
  62. San Gabriel A, Uneyama H (2013) Amino acid sensing in the gastrointestinal tract. Amino Acids 45:451–461CrossRefGoogle Scholar
  63. Shoup FK, Pomeranz Y, Deyoe CW (1966) Amino acid composition of wheat varieties and flours varying widely in bread-making potentialities. J Food Sci 31:94–101CrossRefGoogle Scholar
  64. Slocum RD, Flores HE (1992) Biochemistry and physiology of polyamines in plants. CRC Press, Boca RatonGoogle Scholar
  65. Soda K, Dobashi Y, Kano Y, Tsujinaka S, Konishi F (2009a) Polyamine-rich food decreases age-associated pathology and mortality in aged mice. Exp Gerontol 44:727–732CrossRefGoogle Scholar
  66. Soda K, Kano Y, Sakuragi M, Takao K, Lefor A, Konishi F (2009b) Long-term oral polyamine intake increases blood polyamine concentrations. J Nutr Sci Vitaminol 55:361–366CrossRefGoogle Scholar
  67. Sooranna SR, Hirani J, Das I (1998) Polyamines in pregnancy. Biochem Soc Trans 26:S101CrossRefGoogle Scholar
  68. Tan B, Yin Y, Kong X et al (2010) l-Arginine stimulates proliferation and prevents endotoxin-induced death of intestinal cells. Amino Acids 38:1227–1235CrossRefGoogle Scholar
  69. Tiburcio AF, Alcázar R (2018) Potential applications of polyamines in agriculture and plant biotechnology. Methods Mol Biol 1694:489–508CrossRefGoogle Scholar
  70. Tiburcio AF, Campos JL, Figueras X, Besford RT (1993) Recent advances in the understanding of polyamine functions during plant development. Plant Growth Regul 12:331–340CrossRefGoogle Scholar
  71. USDA (2018) Economic Research Service. Food availability and consumption in the United States. https://www.ers.usda.gov/data-products/ag-and-food-statistics-charting-the-essentials/food-availability-and-consumption.aspx. 2016 data. Accessed 8 March 2019
  72. Venkatachalam M, Sathe SK (2006) Chemical composition of selected edible nut seeds. J Agric Food Chem 54:4705–4714CrossRefGoogle Scholar
  73. Wang HL, Cavins JF (1989) Yield and amino acid composition of fractions obtained during tofu production. Cereal Chem 66:359–361Google Scholar
  74. Wang XQ, Ying W, Dunlap KA, Lin G, Satterfield MC, Burghardt RC, Wu G, Bazer FW (2014) Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian concept uses. Biol Reprod 90:84Google Scholar
  75. Wu G (2009) Amino acids: metabolism, functions, and nutrition. Amino Acids 37:1–17CrossRefGoogle Scholar
  76. Wu G (2013) Amino acids: biochemistry and nutrition. CRC Press, Boca RatonCrossRefGoogle Scholar
  77. Wu G (2016) Dietary protein intake and human health. Food Funct 7:1251–1265CrossRefGoogle Scholar
  78. Wu G (2018) Principles of animal nutrition. CRC Press, Boca RatonGoogle Scholar
  79. Wu G, Wu ZL, Dai ZL, Yang Y, Wang WW, Liu C, Wang B, Wang JJ, Yin YL (2013) Dietary requirements of “nutritionally non-essential amino acids” by animals and humans. Amino Acids 44:1107–1113CrossRefGoogle Scholar
  80. Wu G, Bazer FW, Cross HR (2014) Land-based production of animal protein: impacts, efficiency, and sustainability. Ann NY Acad Sci 1328:18–28CrossRefGoogle Scholar
  81. Wu G, Cross HR, Gehring KB, Savell JW, Arnold AN, McNeill SH (2016) Composition of free and peptide-bound amino acids in beef chuck, loin, and round cuts. J Anim Sci 94:2603–2613CrossRefGoogle Scholar
  82. Wu ZL, Hou YQ, Dai ZL, Hu CA, Wu G (2019) Metabolism, nutrition and redox signaling of hydroxyproline. Antioxid Redox Signal 30:674–682CrossRefGoogle Scholar
  83. Yeoh HH, Truong VD (1996) Amino acid composition and nitrogen-to-protein conversion factors for sweet potato. Trop Sci 36:243–246Google Scholar
  84. Young CT (1980) Amino acid composition of three commercial peanut varieties. J Food Sci 45:1086–1087CrossRefGoogle Scholar
  85. Young VR, Pellett PL (1994) Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr 59:1203S–1212SCrossRefGoogle Scholar
  86. Zoumas-Morse C, Rock CL, Quintana EL, Neuhouser ML, Gerner EW, Meyskens FL (2007) Development of a polyamine database for assessing dietary intake. J Am Diet Assoc 107:1024–1027CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Yongqing Hou
    • 1
  • Wenliang He
    • 2
  • Shengdi Hu
    • 2
  • Guoyao Wu
    • 2
    Email author
  1. 1.Hubei International Scientific and Technological Cooperation Base of Animal Nutrition and Gut HealthWuhan Polytechnic UniversityWuhanChina
  2. 2.Department of Animal Science and Faculty of NutritionTexas A&M UniversityCollege StationUSA

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