Amino Acids

, Volume 51, Issue 4, pp 589–597 | Cite as

Effects of beta-alanine supplementation on muscle function during recovery from resistance exercise in young adults

  • Mirela Casonato Roveratti
  • Jeferson Lucas Jacinto
  • Douglas Bendito Oliveira
  • Rubens Alexandre da Silva
  • Rodrigo Antonio Carvalho Andraus
  • Erick Prado de Oliveira
  • Alex Silva Ribeiro
  • Andreo Fernando AguiarEmail author
Original Article


β-Alanine supplementation has been shown to increase muscle carnosine levels and exercise performance. However, its effects on muscle recovery from resistance exercise (RE) remains unknown. The purpose of this study was to investigate the effects of β-alanine supplementation on muscle function during recovery from a single session of high-intensity RE. Twenty-four untrained young adults (22.1 ± 4.6 years old) were assigned to one of two groups (N = 12 per group): a placebo-supplement group (4.8 g/day) or an β-alanine-supplement group (4.8 g/day). The groups completed a single session of high-intensity RE after 28 days of supplementation and were then evaluated for muscle function on the three subsequent days (at 24, 48, and 72 h postexercise) to assess the time course of muscle recovery. The following indicators of muscle recovery were assessed: number of repetitions until failure, rating of perceived exertion, muscle soreness, and blood levels of creatine kinase (CK). Number of repetitions until failure increased from 24 to 48 h and 72 h of recovery (time P < 0.01), with no difference between groups. There was a significant increase in the rating of perceived exertion among the sets during the RE session (time P < 0.01), with no difference between the groups. No difference was observed over time and between groups in rating of perceived exertion in the functional tests during recovery period. Blood CK levels and muscle soreness increased at 24 h postexercise and then progressively declined at 48 and 72 h postexercise, respectively (time P < 0.05), with no difference between groups. In conclusion, our data indicate that β-alanine supplementation does not improve muscle recovery following a high-intensity RE session in untrained young adults.


Strength training Amino acid Carnosine Muscle performance Muscle recovery 



We address special thanks to all the participants for their engagement in this study.


This study was funding by North University of Paraná (UNOPAR) (grant number: 02.2016).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

This research involved human participants, who were carefully informed of the procedures, risks, and benefits of the investigation and signed an informed consent document approved by the research ethics committee of the University (protocol #1.748.002).

Ethical approval

All procedures were carried out in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Mirela Casonato Roveratti
    • 1
  • Jeferson Lucas Jacinto
    • 1
  • Douglas Bendito Oliveira
    • 1
  • Rubens Alexandre da Silva
    • 2
  • Rodrigo Antonio Carvalho Andraus
    • 1
  • Erick Prado de Oliveira
    • 3
  • Alex Silva Ribeiro
    • 1
  • Andreo Fernando Aguiar
    • 1
    Email author
  1. 1.Center of Research in Health SciencesNorth University of Paraná (UNOPAR)LondrinaBrazil
  2. 2.Département des Sciences de la SantéProgramme de Physiothérapie de L’université McGill Offert em Extension à L’UNIVERSITÉ du Québec à Chicoutimi (UQAC)QuébecCanada
  3. 3.School of MedicineFederal University of UberlandiaUberlândiaBrazil

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