Monatshefte für Chemie - Chemical Monthly

, Volume 151, Issue 1, pp 79–85 | Cite as

A copper-catalyzed multicomponent reaction for the synthesis of thioamide skeletons

  • Mehdi KhalajEmail author
Original Paper


In this report, in situ generated sulfide has been reacted with sulfonylketimine derived from the reaction of alkynes and sulfonyl azides by the action of copper salts to form a wide range of thioamide derivatives. Various terminal alkynes including aromatic, heteroaromatic, and aliphatic alkynes have been well tolerated and the reaction also shows good generality along with azides.

Graphic abstract


Sulfonylketimine 1,8-Diazabicyclo[5.4.0]undec-7-ene Carbon disulfide Sulfonyl azide Terminal alkyne 



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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Young Researchers and Elite Club, Buinzahra BranchIslamic Azad UniversityBuinzahraIran

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